Cloperidone is a quinazolinedione derivative first reported in 1965 by

Miles Laboratories Miles Laboratories (originally the Dr. Miles Medical Company) was a pharmaceutical company founded in Elkhart, Indiana, in 1884 by Dr. Franklin L. Miles, a specialist in the treatment of eye and ear disorders, with an interest in the connection ...

, notable for its

sedative A sedative or tranquilliser is a substance that induces sedation by reducing irritability or Psychomotor agitation, excitement. They are central nervous system (CNS) Depressant, depressants and interact with brain activity, causing its decelera ...

and

antihypertensive Antihypertensives are a class of drugs that are used to treat hypertension (high blood pressure). Antihypertensive therapy seeks to prevent the complications of high blood pressure, such as stroke, heart failure, kidney failure and myocardial infa ...

properties. Its pharmacological activity has been demonstrated in various animal models, including behavioral studies in dogs and cats, as well as

motor coordination In physiology, motor coordination is the orchestrated movement of multiple body parts as required to accomplish intended actions, like walking. This coordination is achieved by adjusting kinematic and kinetic parameters associated with each bo ...

and

locomotor activity Locomotor activity is a measure of animal behavior which is employed in scientific research. Hyperlocomotion, also known as locomotor hyperactivity, hyperactivity, or increased locomotor activity, is an effect of certain drugs in animals in whi ...

assays in mice. Cloperidone is not an approved drug and appears to remain an experimental compound with no current clinical use.

References

{{Hypnotics and sedatives 3-Chlorophenyl compounds Quinazolinones Antihypertensive agents

Sedatives A sedative or tranquilliser is a substance that induces sedation by reducing irritability or excitement. They are central nervous system (CNS) depressants and interact with brain activity, causing its deceleration. Various kinds of sedatives ...

Piperazines