Clinomics is the study of -omics data along with its associated clinical data. The term

-omics Omics is the collective characterization and quantification of entire sets of biological molecules and the investigation of how they translate into the structure, function, and dynamics of an organism or group of organisms. The branches of scien ...

generally refers to a study of biology. As an example,

genomics Genomics is an interdisciplinary field of molecular biology focusing on the structure, function, evolution, mapping, and editing of genomes. A genome is an organism's complete set of DNA, including all of its genes as well as its hierarchical, ...

is the study of the entire

genome A genome is all the genetic information of an organism. It consists of nucleotide sequences of DNA (or RNA in RNA viruses). The nuclear genome includes protein-coding genes and non-coding genes, other functional regions of the genome such as ...

of an organism and was the first -omics term. As personalized medicine advances, clinomics will be a bridge between basic biological data and its effect on human health. As an example, there have been studies of the genes expressed in certain cancer tissues as a way of classification of the cancer and the putative best form of treatment. Already we know that certain genes such as BRCA1 are associated with a higher probability of developing breast cancer. Clinomics takes the next step by looking at not only the genetics of the patient, but also such data as

mRNA In molecular biology, messenger ribonucleic acid (mRNA) is a single-stranded molecule of RNA that corresponds to the genetic sequence of a gene, and is read by a ribosome in the process of Protein biosynthesis, synthesizing a protein. mRNA is ...

metabolites In biochemistry, a metabolite is an intermediate or end product of metabolism. The term is usually used for small molecules. Metabolites have various functions, including fuel, structure, signaling, stimulatory and inhibitory effects on enzymes, c ...

, and

proteins Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residues. Proteins perform a vast array of functions within organisms, including catalysing metabolic reactions, DNA replication, re ...

associated with a patient and a disease.

References

* *{{cite journal , last1=Garman , first1=K. S. , last2=Nevins , first2=J. R. , last3=Potti , first3=A. , title=Genomic strategies for personalized cancer therapy , journal=Human Molecular Genetics , volume=16 , pages=R226–32 , year=2007 , pmid=17911165 , doi=10.1093/hmg/ddm184, doi-access=free Genomics