Claudio Tiribelli (born 6 October 1946) is an Italian hepatologist best known for his studies on

bilirubin Bilirubin (BR) (Latin for "red bile") is a red-orange compound that occurs in the normal catabolic pathway that breaks down heme in vertebrates. This catabolism is a necessary process in the body's clearance of waste products that arise from the ...

and

Kernicterus Kernicterus is a bilirubin-induced brain dysfunction. The term was coined in 1904 by Christian Georg Schmorl. Bilirubin is a naturally occurring substance in the body of humans and many other animals, but it is neurotoxic when its concentratio ...

, a bilirubin-induced neurological condition.

Scientific activity

Since very early in his career, Tiribelli was fascinated by bilirubin. Expanding upon his research activity and expertise, he founded Bilimetrix together with Richard Wennberg. Bilimetrix developed the first point-of-care device for measuring bilirubin in newborns. Early detection of harmful bilirubin levels would prevent neonatal jaundice and allow the newborns to receive timely and proper treatment. Due to his clinical activity and research interests, he is active in translational activity in several liver disorders as

fatty liver disease Fatty liver disease (FLD), also known as hepatic steatosis, is a condition where excess fat builds up in the liver. Often there are no or few symptoms. Occasionally there may be tiredness or pain in the upper right side of the abdomen. Complica ...

and

hepatocellular carcinoma Hepatocellular carcinoma (HCC) is the most common type of primary liver cancer in adults and is currently the most common cause of death in people with cirrhosis. HCC is the third leading cause of cancer-related deaths worldwide. It occurs in th ...

. Together with his longstanding research associate Stefano Bellentani, he designed and performed the Dionysus Study, the first project exploring the prevalence and incidence of liver diseases in the general population. Tiribelli is coordinating a large group of researchers (including postdoctoral fellows, PhD candidates, and senior researchers) located in the hub lab at the Italian Liver Foundation in

Trieste Trieste ( , ; sl, Trst ; german: Triest ) is a city and seaport in northeastern Italy. It is the capital city, and largest city, of the autonomous region of Friuli Venezia Giulia, one of two autonomous regions which are not subdivided into pr ...

. The international programs Claudio is coordinating forces him to cross the Equator 14 times in 2019 (before the COVID pandemic).

Scientific publications

Claudio has over 350 scientific publications, some of his most cited works are: * "Bilirubin-Induced Neurologic Damage — Mechanisms and Management Approaches" * "Prevalence of chronic liver diseases in the general population of Northern Italy: The Dionysos study" * "Prevalence And Risk Factors For Hepatic Steatosis In Northern Italy" * "The fatty liver index: a simple and accurate predictor of hepatic steatosis in the general population" * "Molecular basis and mechanisms of progression of nonalcoholic steatohepatitis (NASH)" *"Intestinal Integrity, the Microbiome and Inflammation"

References

{{DEFAULTSORT:Tiribelli, Claudio 1946 births Living people 21st-century Italian physicians Physicians from Venice Italian hepatologists 20th-century Italian physicians University of Padua alumni Academic staff of the University of Trieste