Cladinose is a
hexose
In chemistry, a hexose is a monosaccharide (simple sugar) with six carbon atoms. The chemical formula for all hexoses is , and their molecular weight is 180.156 g/mol.
Hexoses exist in two forms, open-chain or cyclic, that easily convert into ...
deoxy sugar
Deoxy sugars are sugars that have had a hydroxyl group replaced with a hydrogen atom.
Examples include:
* Deoxyribose, or 2-deoxy-D-ribose, a constituent of DNA
* Fucose, or 6-deoxy-L-galactose, main component of fucoidan of brown algae, and pr ...
that in several
antibiotics
An antibiotic is a type of antimicrobial substance active against bacteria. It is the most important type of antibacterial agent for fighting pathogenic bacteria, bacterial infections, and antibiotic medications are widely used in the therapy ...
(such as
erythromycin
Erythromycin is an antibiotic used for the treatment of a number of bacterial infections. This includes respiratory tract infections, skin infections, chlamydia infections, pelvic inflammatory disease, and syphilis. It may also be used ...
) is attached to the
macrolide
Macrolides are a class of mostly natural products with a large macrocyclic lactone ring to which one or more deoxy sugars, usually cladinose and desosamine, may be attached. Macrolides belong to the polyketide class of natural products. ...
ring.
In
ketolides, a relatively new class of antibiotics, the cladinose is replaced with a
keto group.
External links
*
PubChemDiagrams
References
Deoxy sugars
Monosaccharides
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