Cinnamtannin B1 is a

condensed tannin Condensed tannins (proanthocyanidins, polyflavonoid tannins, catechol-type tannins, pyrocatecollic type tannins, non-hydrolyzable tannins or flavolans) are polymers formed by the condensation of flavans. They do not contain sugar residues. They ...

found in ''

Cinnamomum verum ''Cinnamomum verum'' ( synonym ''Cinnamomum zeylanicum'', also called true cinnamon tree or Ceylon cinnamon tree) is a small evergreen tree belonging to the family Lauraceae, native to Sri Lanka. The inner bark of the tree is historically regard ...

''. It falls under the category of type A proanthocyanidin. Cinnamon could potentially exhibit pharmacological effects in treating

type 2 diabetes mellitus Type 2 diabetes (T2D), formerly known as adult-onset diabetes, is a form of diabetes mellitus that is characterized by high blood sugar, insulin resistance, and relative lack of insulin. Common symptoms include increased thirst, frequent ur ...

and

insulin resistance Insulin resistance (IR) is a pathological response in which cells in insulin-sensitive tissues in the body fail to respond normally to the hormone insulin or downregulate insulin receptors in response to hyperinsulinemia. Insulin is a horm ...

. The plant material predominantly employed in the study was sourced from

Chinese cinnamon ''Cinnamomum cassia'', called Chinese cassia or Chinese cinnamon, is an evergreen tree originating in southern China and widely cultivated there and elsewhere in South and Southeast Asia. It is one of several species of ''Cinnamomum'' used prima ...

(see Chinese cinnamon's medicinal uses). Recent

phytochemical Phytochemicals are naturally-occurring chemicals present in or extracted from plants. Some phytochemicals are nutrients for the plant, while others are metabolites produced to enhance plant survivability and reproduction. The fields of ext ...

research has suggested that cinnamtannin B1, extracted from ''C.

Verum The tee (⊤, \top in LaTeX), also called down tack (as opposed to the up tack) or verum, is a symbol used to represent: * The top element in lattice theory. * The truth value of being true in logic, or a sentence (e.g., formula in propositional ...

,'' might have a potential therapeutic impact on

type 2 diabetes Type 2 diabetes (T2D), formerly known as adult-onset diabetes, is a form of diabetes mellitus that is characterized by high blood sugar, insulin resistance, and relative lack of insulin. Common symptoms include increased thirst, frequent ...

, with the exception of postmenopausal patients studied using ''

Cinnamomum aromaticum ''Cinnamomum cassia'', called Chinese cassia or Chinese cinnamon, is an evergreen tree originating in southern China and widely cultivated there and elsewhere in South Asia, South and Southeast Asia. It is one of several species of ''Cinnamomum' ...

''. Cinnamtannin B1 possesses multiple phenolic hydroxyl groups and is noted for its antioxidant properties, antimicrobial activities, and ability to inhibit platelet aggregation,López, J. J., Jardín, I., Salido, G. M., & Rosado, J. A. (2008). Cinnamtannin B-1 as an antioxidant and platelet aggregation inhibitor. Life sciences, 82(19), 977-982. which could contribute to the protection of damaged tissues in wounds.Fujita K, Kuge K, Ozawa N, Sahara S, Zaiki K, Nakaoji K, et al. (2015) Cinnamtannin B-1 Promotes Migration of Mesenchymal Stem Cells and Accelerates Wound Healing in Mice. PLoS ONE 10(12): e0144166.

References

{{Procyanidin Procyanidins Natural phenol trimers