Cimoxatone (MD 780515) is a
reversible inhibitor of MAO-A
Monoamine oxidase inhibitors (MAOIs) are a class of drugs that inhibit the activity of one or both monoamine oxidase enzymes: monoamine oxidase A (MAO-A) and monoamine oxidase B (MAO-B). They are best known as effective antidepressants, espe ...
(RIMA).
It has a significant food interaction–related adverse effect in combination with
tyramine
Tyramine ( ) (also spelled tyramin), also known under several other names, is a naturally occurring trace amine derived from the amino acid tyrosine. Tyramine acts as a catecholamine releasing agent. Notably, it is unable to cross the blood ...
.
It was never marketed.
See also
*
Monoamine oxidase inhibitor
Monoamine oxidase inhibitors (MAOIs) are a class of drugs that inhibit the activity of one or both monoamine oxidase enzymes: monoamine oxidase A (MAO-A) and monoamine oxidase B (MAO-B). They are best known as effective antidepressants, esp ...
References
Reversible inhibitors of MAO-A
Monoamine oxidase inhibitors
Benzonitriles
3-(4-methoxyphenyl)-2-oxazolidinones
Phenol ethers
{{nervous-system-drug-stub