Christos Ouzounis
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Christos A. Ouzounis is a
computational biologist Computational biology refers to the use of techniques in computer science, data analysis, mathematical modeling and computational simulations to understand biological systems and relationships. An intersection of computer science, biology, and d ...
, a director of research at the CERTH, and Professor of Bioinformatics at
Aristotle University The Aristotle University of Thessaloniki ( AUTh; ), often called the University of Thessaloniki, is the second oldest Tertiary education, tertiary education institution in Greece. Named after the philosopher Aristotle, who was born in Stagira (anc ...
in
Thessaloniki Thessaloniki (; ), also known as Thessalonica (), Saloniki, Salonika, or Salonica (), is the second-largest city in Greece (with slightly over one million inhabitants in its Thessaloniki metropolitan area, metropolitan area) and the capital cit ...
.


Education

Ouzounis received his undergraduate degree (B.Sc.) in Biological Sciences from the
Aristotle University of Thessaloniki The Aristotle University of Thessaloniki ( AUTh; ), often called the University of Thessaloniki, is the second oldest tertiary education institution in Greece. Named after the philosopher Aristotle, who was born in Stageira, about east of Thessa ...
(AUTH) in 1987. He then received an M.Sc. in Biological Computation from the
University of York The University of York (abbreviated as or ''York'' for Post-nominal letters, post-nominals) is a public Collegiate university, collegiate research university in York, England. Established in 1963, the university has expanded to more than thir ...
in 1988 and went on to perform doctoral work with Chris Sander at the
European Molecular Biology Laboratory The European Molecular Biology Laboratory (EMBL) is an intergovernmental organization dedicated to molecular biology research and is supported by 29 member states, two prospect member states, and one associate member state. EMBL was created in ...
in
Heidelberg Heidelberg (; ; ) is the List of cities in Baden-Württemberg by population, fifth-largest city in the States of Germany, German state of Baden-Württemberg, and with a population of about 163,000, of which roughly a quarter consists of studen ...
,
Germany Germany, officially the Federal Republic of Germany, is a country in Central Europe. It lies between the Baltic Sea and the North Sea to the north and the Alps to the south. Its sixteen States of Germany, constituent states have a total popu ...
receiving his
PhD A Doctor of Philosophy (PhD, DPhil; or ) is a terminal degree that usually denotes the highest level of academic achievement in a given discipline and is awarded following a course of graduate study and original research. The name of the deg ...
from the
University of York The University of York (abbreviated as or ''York'' for Post-nominal letters, post-nominals) is a public Collegiate university, collegiate research university in York, England. Established in 1963, the university has expanded to more than thir ...
in 1993.


Career and research

After his PhD, Ouzounis was a Human Frontiers Science Program (HFSP) Postdoctoral fellow at
SRI International SRI International (SRI) is a nonprofit organization, nonprofit scientific research, scientific research institute and organization headquartered in Menlo Park, California, United States. It was established in 1946 by trustees of Stanford Univer ...
,
Menlo Park, California Menlo Park ( ) is a city at the eastern edge of San Mateo County, California, San Mateo County in the San Francisco Bay Area of California, United States. It is bordered by San Francisco Bay on the north and east; East Palo Alto, California, Eas ...
. Ouzounis started his own laboratory, researching computational genomics, at the
European Molecular Biology Laboratory The European Molecular Biology Laboratory (EMBL) is an intergovernmental organization dedicated to molecular biology research and is supported by 29 member states, two prospect member states, and one associate member state. EMBL was created in ...
,
European Bioinformatics Institute The European Bioinformatics Institute (EMBL-EBI) is an intergovernmental organization (IGO) which, as part of the European Molecular Biology Laboratory (EMBL) family, focuses on research and services in bioinformatics. It is located on the Wel ...
(EMBL-EBI) in 1996. He then moved his laboratory to
King's College London King's College London (informally King's or KCL) is a public university, public research university in London, England. King's was established by royal charter in 1829 under the patronage of George IV of the United Kingdom, King George IV ...
(KCL), as a Professor, Chair and Director of the KCL Centre for Bioinformatics in 2007. Following the restructuring at King's in 2009/2010, he returned to
Greece Greece, officially the Hellenic Republic, is a country in Southeast Europe. Located on the southern tip of the Balkan peninsula, it shares land borders with Albania to the northwest, North Macedonia and Bulgaria to the north, and Turkey to th ...
, joining CPERI at CERTH in
Thessaloniki Thessaloniki (; ), also known as Thessalonica (), Saloniki, Salonika, or Salonica (), is the second-largest city in Greece (with slightly over one million inhabitants in its Thessaloniki metropolitan area, metropolitan area) and the capital cit ...
. In 2020 he was appointed as Professor of Bioinformatics at AUTH. His research interests include genome structure, function and evolution, evolution of protein function, evolution of genetic information-processing systems, theory and applications of biological sequence comparison, data and knowledge representation for genomics, unsupervised machine learning in very large datasets, biologically-inspired hardware & software engineering (unpublished works), synthetic biology, exobiology, and science communication. Some of his best known contributions in the field of computational genomics include automated sequence annotation, the discovery of genomic context methods, the inference of metabolic pathways from genome sequences, the development of methods for large-scale clustering of sequence similarities, the definition of the
Last Universal Common Ancestor The last universal common ancestor (LUCA) is the hypothesized common ancestral cell from which the three domains of life, the Bacteria, the Archaea, and the Eukarya originated. The cell had a lipid bilayer; it possessed the genetic code a ...

LUCA
jointly with Nikos Kyrpides, and the quantification of horizontal gene transfer patterns across the "net of life". He also maintains a strong interest in the development of
computational biology Computational biology refers to the use of techniques in computer science, data analysis, mathematical modeling and Computer simulation, computational simulations to understand biological systems and relationships. An intersection of computer sci ...
as an exemplary paradigm in the history of contemporary science, emanating from his first-hand experience that saw bioinformatics grow during the 1990s. He cites as mentors his late father Andreas Ouzounis†, Kostas Kastritsis†, Chris Sander, Antoine Danchin and
Carl Woese Carl Richard Woese ( ; July 15, 1928 – December 30, 2012) was an American microbiologist and biophysicist. Woese is famous for defining the Archaea (a new domain of life) in 1977 through a pioneering phylogenetic taxonomy of 16S ribosomal ...
†. His former PhD students include David Kreil (2001), Anton Enright (2002) JM Peregrin-Alvarez (2003), Victor Kunin (2004) Nikos Darzentas (2005) and Ignat Drozdov (2010).


Awards and honours

Ouzounis is associate editor for the journal ''
PLOS Computational Biology ''PLOS Computational Biology'' is a monthly peer-reviewed open access scientific journal covering computational biology. It was established in 2005 by the Public Library of Science in association with the International Society for Computational B ...
'' (since 2007). He is also an associate editor for the journal ''BioSystems'' and Honorary Editor for the journal ''
Bioinformatics Bioinformatics () is an interdisciplinary field of science that develops methods and Bioinformatics software, software tools for understanding biological data, especially when the data sets are large and complex. Bioinformatics uses biology, ...
''. He is a founding officer of the
International Society for Computational Biology The International Society for Computational Biology (ISCB) is a scholarly society for researchers in computational biology and bioinformatics. The society was founded in 1997 to provide a stable financial home for the Intelligent Systems for Mo ...
(ISCB), th
Mikrobiokosmos
initiative (Greece), the Hellenic Society for Computational Biology & Bioinformatics an
Hellenic Bioinformatics
He is an active member of th
MetaSUB
consortium and a board member o
Elixir-Europe
He was a visiting professor at the
University of Toronto The University of Toronto (UToronto or U of T) is a public university, public research university whose main campus is located on the grounds that surround Queen's Park (Toronto), Queen's Park in Toronto, Ontario, Canada. It was founded by ...
(2011-2014). He is also a committed adventurer/photographer and a trained RYA windsurfing instructor / amateur windsurfing coach.


References

{{DEFAULTSORT:Ouzounis, Christos Living people Computational biologists Greek bioinformaticians Aristotle University of Thessaloniki alumni Alumni of the University of York Greek expatriates in the United Kingdom Academic journal editors 1965 births