Christine Loscher
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Christine E. Loscher is a Professor of Biotechnology and Associate Dean for Research at
Dublin City University Dublin City University (abbreviated as DCU) () is a Third-level education in the Republic of Ireland, university based on the Northside, Dublin, Northside of Dublin, Republic of Ireland, Ireland. Created as the ''National Institute for Highe ...
. Loscher is director of the Health Technologies Research and Enterprise Hub, and she works on bioactive molecules for
autoimmune disease An autoimmune disease is a condition that results from an anomalous response of the adaptive immune system, wherein it mistakenly targets and attacks healthy, functioning parts of the body as if they were foreign organisms. It is estimated tha ...
s.


Early life and education

During her undergraduate studies at the
Dublin Institute of Technology Dublin Institute of Technology (DIT, ) was a major third-level institution in Dublin, Ireland. On 1 January 2019 DIT was dissolved and its functions were transferred to the Technological University Dublin, as TU Dublin City Campus. The insti ...
, Loscher worked with
Cliona O’Farrelly Cliona O’Farrelly is an Irish immunologist, with a background in comparative, liver and cancer immunology, focuses on the innate immune response to viruses to identify new or improved therapeutic strategies to control resistance to viral infectio ...
at St. Vincent's University Hospital. Loscher earned her PhD at the
National University of Ireland The National University of Ireland (NUI) () is a federal university system of ''constituent universities'' (previously called '' constituent colleges'') and ''recognised colleges'' set up under the Irish Universities Act 1908, and signifi ...
in 2000. Following her graduate studies, Loscher joined
Trinity College Dublin Trinity College Dublin (), officially titled The College of the Holy and Undivided Trinity of Queen Elizabeth near Dublin, and legally incorporated as Trinity College, the University of Dublin (TCD), is the sole constituent college of the Unive ...
as a
postdoctoral researcher A postdoctoral fellow, postdoctoral researcher, or simply postdoc, is a person professionally conducting research after the completion of their doctoral studies (typically a PhD). Postdocs most commonly, but not always, have a temporary acade ...
. She worked with Kingston Mills on how vaccines can trigger fevers. In 2003 she was appointed to the
St. James's Hospital St. James's Hospital ''Confirms spelling of name as "James's" and Irish name'' () is a teaching hospital in Dublin, Republic of Ireland, Ireland. Its academic partner is Trinity College Dublin. It is managed by Dublin Midlands Hospital Group. ...
Institute of Molecular Medicine.


Career

Loscher joined
Dublin City University Dublin City University (abbreviated as DCU) () is a Third-level education in the Republic of Ireland, university based on the Northside, Dublin, Northside of Dublin, Republic of Ireland, Ireland. Created as the ''National Institute for Highe ...
in 2005. She established the ''Immunomodulation Research Group'' with Helen Roche. She also directs the Nano-Bioanalytical Research Facility. She looks at how modulating the immune response can improve health, developing new
anti-inflammatory Anti-inflammatory is the property of a substance or treatment that reduces inflammation, fever or swelling. Anti-inflammatory drugs, also called anti-inflammatories, make up about half of analgesics. These drugs reduce pain by inhibiting mechan ...
compounds for the pharmaceutical and food industry. She investigates bioactive molecules in marine mash. Whilst the immune system may be best known for fighting disease, it is sometimes triggered into
chronic inflammation Chronic systemic inflammation is the result of release of pro-inflammatory cytokines from immune-related cells and the chronic activation of the innate immune system. It can contribute to the development or progression of certain conditions such ...
. She has described her work to the
Irish Independent The ''Irish Independent'' is an Irish daily newspaper A newspaper is a Periodical literature, periodical publication containing written News, information about current events and is often typed in black ink with a white or gray backgrou ...
. She served as Principal Investigator for the research consortium ''Food for Health Ireland'', an organisation that partners academics with Irish dairy and ingredient companies. She has worked with
Teagasc Teagasc (, meaning "Instruction") is the State-sponsored bodies of the Republic of Ireland, semi-state authority in Republic of Ireland, Ireland responsible for research and development, training and advisory services in the agri-food sector. The ...
to identify ingredients that can help
lactose intolerance Lactose intolerance is caused by a lessened ability or a complete inability to digest lactose, a sugar found in dairy products. Humans vary in the amount of lactose they can tolerate before symptoms develop. Symptoms may include abdominal pain ...
infants. She discovered how the immune system responds to
Clostridioides difficile ''Clostridioides difficile'' ( syn. ''Clostridium difficile'') is a bacterium known for causing serious diarrheal infections, and may also cause colon cancer. It is known also as ''C. difficile'', or ''C. diff'' (), and is a Gram-positive spec ...
- outer proteins trigger immune responses. Loscher serves on the Irish Society of Immunology.


Public engagement

Loscher runs ResearchFest, a strand of
InspireFest Silicon Republic (domain:SiliconRepublic.com) is an Irish technology news website An online newspaper (or electronic news or electronic news publication) is the electronic publishing, online version of a newspaper, either as a stand-alone publi ...
, where researchers give short talks about their work. In 2016 she announced that
Dublin City University Dublin City University (abbreviated as DCU) () is a Third-level education in the Republic of Ireland, university based on the Northside, Dublin, Northside of Dublin, Republic of Ireland, Ireland. Created as the ''National Institute for Highe ...
would name half of its buildings after inspirational women. She contributed to the
Royal Society of Chemistry The Royal Society of Chemistry (RSC) is a learned society and professional association in the United Kingdom with the goal of "advancing the chemistry, chemical sciences". It was formed in 1980 from the amalgamation of the Chemical Society, the ...
Innate Immunology Summit. She was selected by Silicon Republic as one of the ''Women Invent Tomorrow'' in 204 and Top 100 Women in Science in 2016. She delivered a
TED Talk TED Conferences, LLC (Technology, Entertainment, Design) is an American-Canadian non-profit media organization that posts international talks online for free distribution under the slogan "Ideas Change Everything" (previously "Ideas Worth Sprea ...
on the Future of Food. In 2018 she was incldued by ''Silicon Republic'' in a list of 22 "high-flying scientists".


References

{{DEFAULTSORT:Loscher, Christine Year of birth missing (living people) Living people Women immunologists Irish immunologists Irish women scientists Women science writers Academics of Dublin City University Alumni of Trinity College Dublin