Cholest-4-en-3-one 26-monooxygenase (, ''CYP125'', ''CYP125A1'', ''cholest-4-en-3-one 27-monooxygenase'') is an
enzyme
Enzymes () are proteins that act as biological catalysts by accelerating chemical reactions. The molecules upon which enzymes may act are called substrate (chemistry), substrates, and the enzyme converts the substrates into different molecule ...
with
systematic name A systematic name is a name given in a systematic way to one unique group, organism, object or chemical substance, out of a specific population or collection. Systematic names are usually part of a nomenclature.
A semisystematic name or semitrivial ...
''cholest-4-en-3-one,NADH:oxygen oxidoreductase (26-hydroxylating)''.
This enzyme
catalyses the following
chemical reaction
A chemical reaction is a process that leads to the chemical transformation of one set of chemical substances to another. Classically, chemical reactions encompass changes that only involve the positions of electrons in the forming and break ...
: cholest-4-en-3-one + NADH + H
+ + O
2 26-hydroxycholest-4-en-3-one + NAD
+ + H
2O
Cholest-4-en-3-one 26-monooxygenase is a
heme
Heme, or haem (pronounced / hi:m/ ), is a precursor to hemoglobin, which is necessary to bind oxygen in the bloodstream. Heme is biosynthesized in both the bone marrow and the liver.
In biochemical terms, heme is a coordination complex "consis ...
thiol
In organic chemistry, a thiol (; ), or thiol derivative, is any organosulfur compound of the form , where R represents an alkyl or other organic substituent. The functional group itself is referred to as either a thiol group or a sulfhydryl gro ...
ate (P450) enzyme.
References
External links
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EC 1.14.13