Cholest-4-en-3-one 26-monooxygenase (, ''CYP125'', ''CYP125A1'', ''cholest-4-en-3-one 27-monooxygenase'') is an
enzyme
An enzyme () is a protein that acts as a biological catalyst by accelerating chemical reactions. The molecules upon which enzymes may act are called substrate (chemistry), substrates, and the enzyme converts the substrates into different mol ...
with
systematic name
A systematic name is a name given in a systematic way to one unique group, organism, object or chemical substance, out of a specific population or collection. Systematic names are usually part of a nomenclature.
A semisystematic name or semitrivi ...
''cholest-4-en-3-one,NADH:oxygen oxidoreductase (26-hydroxylating)''.
This enzyme
catalyses the following
chemical reaction
A chemical reaction is a process that leads to the chemistry, chemical transformation of one set of chemical substances to another. When chemical reactions occur, the atoms are rearranged and the reaction is accompanied by an Gibbs free energy, ...
: cholest-4-en-3-one + NADH + H
+ + O
2 26-hydroxycholest-4-en-3-one + NAD
+ + H
2O
Cholest-4-en-3-one 26-monooxygenase is a
heme
Heme (American English), or haem (Commonwealth English, both pronounced /Help:IPA/English, hi:m/ ), is a ring-shaped iron-containing molecule that commonly serves as a Ligand (biochemistry), ligand of various proteins, more notably as a Prostheti ...
thiol
In organic chemistry, a thiol (; ), or thiol derivative, is any organosulfur compound of the form , where R represents an alkyl or other organic substituent. The functional group itself is referred to as either a thiol group or a sulfhydryl grou ...
ate (P450) enzyme.
References
External links
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EC 1.14.13