''Acanthocystis turfacea chlorella virus 1'' (''ATCV-1''), also called Chlorovirus ATCV-1 or Chlorella virus ATCV-1 is a species of giant double-stranded

DNA virus A DNA virus is a virus that has a genome made of deoxyribonucleic acid (DNA) that is replicated by a DNA polymerase. They can be divided between those that have two strands of DNA in their genome, called double-stranded DNA (dsDNA) viruses, and ...

in the genus ''

Chlorovirus ''Chlorovirus'', also known as Chlorella virus, is a genus of giant double-stranded DNA viruses, in the family '' Phycodnaviridae''. This genus is found globally in freshwater environments where freshwater microscopic algae serve as natural hos ...

''. The host of ATCV-1 is ''

Chlorella heliozoae ''Chlorella'' is a genus of about thirteen species of single-celled green algae belonging to the division Chlorophyta. The cells are spherical in shape, about 2 to 10 μm in diameter, and are without flagella. Their chloroplasts contain the gr ...

''; it was demonstrated that "ATCV-1 neither attaches to nor infects"

Chlorella variabilis ''Chlorella'' is a genus of about thirteen species of single-celled green algae belonging to the division Chlorophyta. The cells are spherical in shape, about 2 to 10 μm in diameter, and are without flagella. Their chloroplasts contain the gr ...

Human infection

DNA from ATCV-1 has been isolated from the mucous membranes of the noses of humans. In both humans and mice, the presence of ATCV-1 on the

oropharyngeal The pharynx (plural: pharynges) is the part of the throat behind the mouth and nasal cavity, and above the oesophagus and trachea (the tubes going down to the stomach and the lungs). It is found in vertebrates and invertebrates, though its struc ...

mucosa was associated with lower scores in tests of cognitive and motor skills. Injection of purified algal virus ATCV-1 intracranially results in long-lasting cognitive and behavioural effects in mice via induction of inflammatory factors.

References

External links

* {{Taxonbar, from=Q18657978 Phycodnaviridae