Chlorosipentramine is an analogue of the
anorectic
An anorectic is a drug that reduces appetite, resulting in lower food consumption, leading to weight loss. These substances work by affecting the central nervous system or certain neurotransmitters to create a feeling of fullness or reduce the desi ...
drug
sibutramine
Sibutramine, formerly sold under the brand name Meridia among others, is an appetite suppressant which has been discontinued in many countries. It works as a serotonin–norepinephrine reuptake inhibitor (SNRI) similar to certain antidepressant ...
, which has been sold as an ingredient in
weight loss
Weight loss, in the context of medicine, health, or physical fitness, refers to a reduction of the total body mass, by a mean loss of fluid, body fat (adipose tissue), or lean mass (namely bone mineral deposits, muscle, tendon, and other conn ...
products sold as
dietary supplement
A dietary supplement is a manufactured product intended to supplement a person's diet by taking a pill (pharmacy), pill, capsule (pharmacy), capsule, tablet (pharmacy), tablet, powder, or liquid. A supplement can provide nutrients eithe ...
s, first detected in South Korea in 2017.
It is one of a number of sibutramine derivatives which have been sold in grey-market weight loss products since sibutramine itself was taken off the market due to safety concerns. Others include
desmethylsibutramine,
didesmethylsibutramine, homosibutramine,
chlorosibutramine, and benzylsibutramine.
Chlorosipentramine is illegal in South Korea along with other related compounds.
See also
*
3F-PiHP
3F-PiHP (3F-α-PiHP) is a recreational designer drug from the substituted cathinone family, with stimulant effects. It was first identified in both Sweden and Finland in mid-2019, and was made illegal in Finland in August 2019.
See also
* 3-Flu ...
*
4-Cl-PHP
4-Chloro-alpha-Pyrrolidinohexiophenone (4-Cl-PHP) is a substituted cathinone derivative with stimulant effects, which has been sold as a designer drug. It was first officially identified by forensic laboratories in 2016, though anecdotal reports ...
*
O-2390
O-2390 (3,4-Dichloro-alpha-PVP, DCPVP) is a recreational designer drug from the substituted cathinone family, which acts as a potent inhibitor of dopamine and noradrenaline reuptake ''in vitro'', with weaker but still significant inhibition of se ...
*
1-Methyl-3-propyl-4-(p-chlorophenyl)piperidine
1-Methyl-3-propyl-4-(''p''-chlorophenyl)piperidine is a drug developed by a team led by Alan Kozikowski, which acts as a potent dopamine reuptake inhibitor, and was developed as a potential therapeutic agent for the treatment of cocaine addicti ...
*
JZ-IV-10
JZ-IV-10 is a piperidine derivative related to cocaine which acts as a highly potent serotonin–norepinephrine–dopamine reuptake inhibitor (also called SNDRI, or triple reuptake inhibitor). The eugeroic modafinil was used as a lead to fuel th ...
References
Anorectics
Chlorobenzene derivatives
Cyclobutanes
Phenethylamines
Serotonin–norepinephrine–dopamine reuptake inhibitors
Stimulants
Substituted amphetamines
Dimethylamino compounds
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