Chlamydia research is the systematic study of the organisms in the taxonomic group of bacteria

Chlamydiota The Chlamydiota (synonym Chlamydiae) are a bacterial phylum and class whose members are remarkably diverse, including pathogens of humans and animals, symbionts of ubiquitous protozoa, and marine sediment forms not yet well understood. All of ...

(formerly Chlamydiae), the diagnostic procedures to treat infections, the disease

chlamydia Chlamydia, or more specifically a chlamydia infection, is a sexually transmitted infection caused by the bacterium ''Chlamydia trachomatis''. Most people who are infected have no symptoms. When symptoms do appear, they may occur only several w ...

, infections caused by the organisms, the epidemiology of infection and the development of vaccines. The process of research can include the participation of many researchers who work in collaboration from separate organizations, governmental entities and universities.

Funding

The

Centers for Disease Control and Prevention The Centers for Disease Control and Prevention (CDC) is the National public health institutes, national public health agency of the United States. It is a Federal agencies of the United States, United States federal agency under the United S ...

(CDC) offers funding to research the

biology Biology is the scientific study of life and living organisms. It is a broad natural science that encompasses a wide range of fields and unifying principles that explain the structure, function, growth, History of life, origin, evolution, and ...

, physiology, epidemiology, vaccine development, and publish systematic reviews of Chlamydia species. Other funding sources include the National Chlamydia Coalition.

Institutes

NIAID

Studies continue to determine the organism's genetic makeup. NIAID-supported scientists have determined the complete genome (genetic blueprint) for C. trachomatis.

Max Planck Institute for Infection Biology

The

Max Planck Institute for Infection Biology The Max Planck Institute for Infection Biology (MPIIB) is a non-university research institute of the Max Planck Society located in the heart of Berlin in Berlin-Mitte. It was founded in 1993. Arturo Zychlinsky is currently the Managing Director. ...

continues its research into chlamydia infection. The institute has published over 140 studies related to chlamydia.

Queensland University of Technology

There are research projects in several areas at the

Queensland University of Technology The Queensland University of Technology (QUT) is a public university, public research university located in the city of Brisbane in Queensland, Australia. It has two major campuses, a modern city campus in Gardens Point, Brisbane, Gardens Point ...

, including development of a human vaccine for chlamydial sexually transmitted disease and understanding basic mechanisms of regulation, including the importance of chlamydial

protease A protease (also called a peptidase, proteinase, or proteolytic enzyme) is an enzyme that catalysis, catalyzes proteolysis, breaking down proteins into smaller polypeptides or single amino acids, and spurring the formation of new protein products ...

s. Chlamydia infections in wildlife are part of the research into chlamydia, particularly koalas' genomics and gene regulation studies in chlamydia. A sample list of primary publications: :10.1111/j.1574-695X.2011.00843.x :10.1186/1471-2334-6-152

University of Southampton

Vaccine development at the

University of Southampton The University of Southampton (abbreviated as ''Soton'' in post-nominal letters) is a public university, public research university in Southampton, England. Southampton is a founding member of the Russell Group of research-intensive universit ...

continues.

Vaccine

Vaccine research is ongoing in independent and institutional settings. CTH522 has completed phase 1 trials

Clinical studies

Clinical trials

Clinical trials are used by researchers investigating the efficacy of interventions or protocol in the epidemiology, detection, prevention and treatment of chlamydia infections. Interventions are the use of medical products, medication, devices, procedures or changes in the participants' behavior. The effects on the participants are measured and compared to previous trials, placebo or a new medical approach, or to no intervention. The National Institutes of Health support ongoing research in the study of chlamydia infection. At least 113 studies have been initiated as of 2015. One example was the clinical trial of eye prophylaxis in newborns in the prevention of neonatal conjunctivitis caused by Chlamydia trachomatis.

Observational studies

Research related to chlamydia can take the form of an observational study. This type of study assesses outcomes in groups of participants according to a research plan or protocol. The volunteers in the study may receive interventions such as medical products, medications, devices, or procedures as part of their routine medical care. The volunteers in this type of study are not assigned to specific interventions as in a clinical trial. An example of an observational study regarding chlamydia infection was "Non-Invasive Sexually Transmitted Disease (STD) Testing in Women Seeking Emergency Contraception or Urine Pregnancy Testing: Meeting the Needs of an At-Risk Population" in 2010. Observational studies employ the use of randomised control studies.

Case studies

Case studies that research the prevalence and prevention of chlamydia can include personal contact, a detailed history of the participants, extensive physical examinations, and related contextual conditions. Chlamydia case studies also can be produced by following a formal research method. These case studies are likely to appear in formal research venues, such as journals, professional conferences, and administrative science. In doing case study research, the case being studied may be an individual, organization, event, or action, existing in a specific time and place. For instance, clinical science has produced both well-known case studies of individuals and also case studies of clinical practices.

Evidence-based research

Evidence-based medicine Evidence-based medicine (EBM) is "the conscientious, explicit and judicious use of current best evidence in making decisions about the care of individual patients. It means integrating individual clinical expertise with the best available exte ...

chlamydia studies optimizes

decision-making In psychology, decision-making (also spelled decision making and decisionmaking) is regarded as the Cognition, cognitive process resulting in the selection of a belief or a course of action among several possible alternative options. It could be ...

by employing the use of information based upon well-designed

research Research is creative and systematic work undertaken to increase the stock of knowledge. It involves the collection, organization, and analysis of evidence to increase understanding of a topic, characterized by a particular attentiveness to ...

. This approach to the study of chlamydia requires that only research conducted coming from

meta-analyses Meta-analysis is a method of synthesis of quantitative data from multiple independent studies addressing a common research question. An important part of this method involves computing a combined effect size across all of the studies. As such, th ...

systematic review A systematic review is a scholarly synthesis of the evidence on a clearly presented topic using critical methods to identify, define and assess research on the topic. A systematic review extracts and interprets data from published studies on ...

s, and

randomized controlled trial A randomized controlled trial (or randomized control trial; RCT) is a form of scientific experiment used to control factors not under direct experimental control. Examples of RCTs are clinical trials that compare the effects of drugs, surgical ...

s) can yield widely applied recommendations. Some examples of evidence-based research on chlamydia include: * Chlamydia trachomatis and Genital Mycoplasmas: Pathogens with an Impact on Human Reproductive Health. Ljubin-Sternak S, Meštrović T. Journal Pathog. 2014;2014:183167. doi: 10.1155/2014/183167. Epub 2014 Dec 31. * Screening for Gonorrhea and Chlamydia: Systematic Review to Update the U.S. Preventive Services Task Force Recommendations nternet Nelson HD, Zakher B, Cantor A, Deagas M, Pappas M.Rockville (MD): Agency for Healthcare Research and Quality (US); 2014 Sep.

References

Using Wikipedia for Research

External links

Case studies from the National Chlamydia Coalition

Jackson County Health Department

SUNY/Buffalo

Michigan Department of Community Health

Old Dominion University

Maryland Department of Juvenile Services

Minnesota Department of Health
{{Authority control Sexually transmitted diseases and infections Bacterial diseases Chlamydia infections Infections with a predominantly sexual mode of transmission Chlamydiota Medical research