Charles Weissmann (born 14 October 1931) is a Hungarian-

Swiss Swiss may refer to: * the adjectival form of Switzerland * Swiss people Places * Swiss, Missouri *Swiss, North Carolina * Swiss, West Virginia * Swiss, Wisconsin Other uses * Swiss-system tournament, in various games and sports *Swiss Internati ...

molecular biologist. Weissmann is particularly known for the first cloning and expression of

interferon Interferons (IFNs, ) are a group of signaling proteins made and released by host cells in response to the presence of several viruses. In a typical scenario, a virus-infected cell will release interferons causing nearby cells to heighten t ...

and his contributions to the unraveling of the molecular genetics of neurogenerative

prion Prions are misfolded proteins that have the ability to transmit their misfolded shape onto normal variants of the same protein. They characterize several fatal and transmissible neurodegenerative diseases in humans and many other animals. It ...

diseases such as

scrapie Scrapie () is a fatal, degenerative disease affecting the nervous systems of sheep and goats. It is one of several transmissible spongiform encephalopathies (TSEs), and as such it is thought to be caused by a prion. Scrapie has been known since ...

Creutzfeldt–Jakob disease Creutzfeldt–Jakob disease (CJD), also known as subacute spongiform encephalopathy or neurocognitive disorder due to prion disease, is an invariably fatal degenerative brain disorder. Early symptoms include memory problems, behavioral changes ...

and "

mad cow disease Bovine spongiform encephalopathy (BSE), commonly known as mad cow disease, is an incurable and invariably fatal neurodegenerative disease of cattle. Symptoms include abnormal behavior, trouble walking, and weight loss. Later in the course of t ...

". Weissmann went to

University of Zurich The University of Zürich (UZH, german: Universität Zürich) is a public research university located in the city of Zürich, Switzerland. It is the largest university in Switzerland, with its 28,000 enrolled students. It was founded in 1833 ...

and obtained his MD in 1956 and Ph.D. in

Organic Chemistry Organic chemistry is a subdiscipline within chemistry involving the science, scientific study of the structure, properties, and reactions of organic compounds and organic materials, i.e., matter in its various forms that contain carbon atoms.Clay ...

in 1961. In 1978, Weissmann co-founded the biotech company

Biogen Biogen Inc. is an American multinational biotechnology company based in Cambridge, Massachusetts, specializing in the discovery, development, and delivery of therapies for the treatment of neurological diseases to patients worldwide. History ...

Geneva Geneva ( ; french: Genève ) frp, Genèva ; german: link=no, Genf ; it, Ginevra ; rm, Genevra is the second-most populous city in Switzerland (after Zürich) and the most populous city of Romandy, the French-speaking part of Switzerland. Situ ...

. Biogen is considered one of the pioneers of the

biotechnology Biotechnology is the integration of natural sciences and engineering sciences in order to achieve the application of organisms, cells, parts thereof and molecular analogues for products and services. The term ''biotechnology'' was first used b ...

industries. Weissmann was director of the Institute for Molecular Biology in Zurich, President of the

Roche Research Foundation F. Hoffmann-La Roche AG, commonly known as Roche, is a Swiss multinational healthcare company that operates worldwide under two divisions: Pharmaceuticals and Diagnostics. Its holding company, Roche Holding AG, has shares listed on the SIX ...

and co-founder and Member of the Scientific Council of Biogen. He was Chairman of the Department of Infectology, Scripps Florida until 2011. Weissmann won several awards, including the

Otto Warburg Medal The Otto Warburg Medal is awarded annually by the German Society for Biochemistry and Molecular Biology (German: ''Gesellschaft für Biochemie und Molekularbiologie'' or ''GBM'') to honour scientists who have contributed important work in the field ...

(1980) and the Scheele Award (1982). A member of the American Society of Biological Chemistry and the Deutsche Akademie der Naturforscher Leopoldina he is also a Foreign Associate of the U.S.

National Academy of Sciences The National Academy of Sciences (NAS) is a United States nonprofit, non-governmental organization. NAS is part of the National Academies of Sciences, Engineering, and Medicine, along with the National Academy of Engineering (NAE) and the Nat ...

, the

Royal Society The Royal Society, formally The Royal Society of London for Improving Natural Knowledge, is a learned society and the United Kingdom's national academy of sciences. The society fulfils a number of roles: promoting science and its benefits, r ...

(UK) and the

Pour le Mérite The ' (; , ) is an order of merit (german: Verdienstorden) established in 1740 by King Frederick II of Prussia. The was awarded as both a military and civil honour and ranked, along with the Order of the Black Eagle, the Order of the Red Ea ...

(Germany). On May 16, 2011 Weissmann became Doctor of Science Honoris Causa at New York University.

Awards

Sir Hans Krebs Medal The Sir Hans Krebs Lecture and Medal is awarded annually by the Federation of European Biochemical Societies (FEBS) for outstanding achievements in Biochemistry and Molecular Biology or related sciences. It was endowed by the Lord Rank Centre for ...

(1974). *

(1980). * Scheele Award (1982). *

Wilhelm Exner Medal The Wilhelm Exner Medal has been awarded by the Austrian Industry Association, (ÖGV), for excellence in research and science since 1921. The medal is dedicated to Wilhelm Exner (1840–1931), former president of the Association, who initialize ...

(1996).Editor, ÖGV. (2015). Wilhelm Exner Medal. Austrian Trade Association. ÖGV. Austria. *

Max Delbrück Medal The Max Delbrück Medal has been awarded annually from 1992 to 2013 by the Max Delbrück Center for Molecular Medicine (German: ''Max-Delbrück-Centrum für Molekulare Medizin'' or MDC). Named after the German biophysicist Max Delbrück, it is pr ...

(1997) * Mendel Medal (1998)

References

External links

Profile at The Scripps Research Institute

"Dart/NYU Biotechnology Achievement Award"
1931 births Living people Jewish scientists Swiss biologists Scientists from Budapest Hungarian Jews Hungarian emigrants to Switzerland University of Zurich alumni Foreign Members of the Royal Society Recipients of the Pour le Mérite (civil class) Scripps Research faculty Foreign associates of the National Academy of Sciences Winners of the Heineken Prize Fellows of the American Academy of Microbiology {{Switzerland-scientist-stub