Charles James Martin (physiologist)
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Sir Charles James Martin was a British scientist and director of the
Lister Institute of Preventive Medicine The Lister Institute of Preventive Medicine, informally known as the Lister Institute, was established as a research institute (the British Institute of Preventive Medicine) in 1891, with bacteriologist Marc Armand Ruffer as its first director, ...
, who did seminal work on a wide range of topics including snake
toxin A toxin is a naturally occurring poison produced by metabolic activities of living cells or organisms. They occur especially as proteins, often conjugated. The term was first used by organic chemist Ludwig Brieger (1849–1919), derived ...
s, control of body temperature, plague and the way it was spread,
dysentery Dysentery ( , ), historically known as the bloody flux, is a type of gastroenteritis that results in bloody diarrhea. Other symptoms may include fever, abdominal pain, and a feeling of incomplete defecation. Complications may include dehyd ...
,
typhoid Typhoid fever, also known simply as typhoid, is a disease caused by ''Salmonella enterica'' serotype Typhi bacteria, also called ''Salmonella'' Typhi. Symptoms vary from mild to severe, and usually begin six to 30 days after exposure. Often ther ...
and paratyphoid.


Early life

Born in Wilmot House,
Dalston Dalston () is an area of East London, in the London Borough of Hackney. It is northeast of Charing Cross. Dalston began as a hamlet on either side of Dalston Lane, and as the area urbanised the term also came to apply to surrounding areas i ...
,Chick: ''Sir Charles James Martin(1866–1955)'', rev. Oxford Dictionary of National Biography, Oxford University Press, 2004; online edn, Oct 2009, accessed 14 Jan 2013
/ref> he was the twelfth child of Josiah (an insurance company actuary) and Elizabeth Mary Martin (née Lewis), Charles James was part of an extended family of children from his parents' previous marriages. Being a delicate child, he was sent off to a private boarding school in
Hastings Hastings ( ) is a seaside town and Borough status in the United Kingdom, borough in East Sussex on the south coast of England, east of Lewes and south east of London. The town gives its name to the Battle of Hastings, which took place to th ...
. At 15 he was employed as a junior clerk at the insurance firm where his father worked. He studied mathematics as a requirement for a future as actuary, but showed no special aptitude. Browsing through the numerous bookshops in the area, he came across a secondhand copy of ''"A Hundred Experiments in Chemistry for One Shilling."'' Carrying out these experiments, he was sufficiently inspired to entreat his father to allow him to pursue a career in science. He accordingly took evening classes at
King's College, London King's College London (informally King's or KCL) is a public university, public research university in London, England. King's was established by royal charter in 1829 under the patronage of George IV of the United Kingdom, King George IV ...
. He then studied medicine at St Thomas's Hospital and spent some time in Leipzig studying physiology under Karl Ludwig.


Career

In 1891 he accepted a post as lecturer at
Sydney University The University of Sydney (USYD) is a public university, public research university in Sydney, Australia. Founded in 1850, it is the oldest university in both Australia and Oceania. One of Australia's six sandstone universities, it was one of the ...
, before moving to the
University of Melbourne The University of Melbourne (colloquially known as Melbourne University) is a public university, public research university located in Melbourne, Australia. Founded in 1853, it is Australia's second oldest university and the oldest in the state ...
as acting Professor of Physiology. He remained in Australia for 12 years, after which he returned to the UK to become the first Director of the
Lister Institute of Preventive Medicine The Lister Institute of Preventive Medicine, informally known as the Lister Institute, was established as a research institute (the British Institute of Preventive Medicine) in 1891, with bacteriologist Marc Armand Ruffer as its first director, ...
. He was elected a
Fellow of the Royal Society Fellowship of the Royal Society (FRS, ForMemRS and HonFRS) is an award granted by the Fellows of the Royal Society of London to individuals who have made a "substantial contribution to the improvement of natural science, natural knowledge, incl ...
in 1901. His candidacy citation read: During
World War I World War I or the First World War (28 July 1914 – 11 November 1918), also known as the Great War, was a World war, global conflict between two coalitions: the Allies of World War I, Allies (or Entente) and the Central Powers. Fighting to ...
he served with the
Australian Army Medical Corps The Royal Australian Army Medical Corps (RAAMC) is the branch of the Australian Army responsible for providing medical care to Army personnel. The AAMC was formed in 1902 through the amalgamation of medical units of the various Australian colon ...
in
Gallipoli The Gallipoli Peninsula (; ; ) is located in the southern part of East Thrace, the European part of Turkey, with the Aegean Sea to the west and the Dardanelles strait to the east. Gallipoli is the Italian form of the Greek name (), meaning ' ...
, Egypt, and France as a pathologist with the rank of Lieutenant-colonel. He found some cases of enteric fever at Gallipoli were not typhoid, but paratyphoids A and B, and made a vaccine for all three. A memo to his colleagues on the different treatments for amoebic and bacillary dysentery was widely circulated by the army under Martin’s name. In France he organized the integration of decentralized pathology services into the A.A.M.C. After the war he returned to the Lister Institute until his retirement in 1930. He then spent a further two years in Australia as head of the animal nutrition division of the Council of Scientific and Industrial Research in Adelaide. On his return to the UK he went to live at Roebuck House in Old Chesterton,
Cambridge Cambridge ( ) is a List of cities in the United Kingdom, city and non-metropolitan district in the county of Cambridgeshire, England. It is the county town of Cambridgeshire and is located on the River Cam, north of London. As of the 2021 Unit ...
, which he equipped as a laboratory. During WWII it was used to rehouse the experimental animals being used for medical studies by the staff of the Lister Institute. In 1934 he undertook an experimental study of the myxoma virus, at Cambridge and on a rabbit-infested island in Pembrokeshire, to show it was both safe and effective to control plagues of rabbits. He was awarded the Royal Society's
Royal Medal The Royal Medal, also known as The Queen's Medal and The King's Medal (depending on the gender of the monarch at the time of the award), is a silver-gilt medal, of which three are awarded each year by the Royal Society. Two are given for "the mo ...
in 1923 and delivered the
Royal College of Physicians The Royal College of Physicians of London, commonly referred to simply as the Royal College of Physicians (RCP), is a British professional membership body dedicated to improving the practice of medicine, chiefly through the accreditation of ph ...
Croonian Lecture The Croonian Medal and Lecture is a prestigious award, a medal, and lecture given at the invitation of the Royal Society and the Royal College of Physicians. Among the papers of William Croone at his death in 1684, was a plan to endow a singl ...
s in 1930. He was knighted in the 1927 birthday honours. His contributions to the foundation of biological science in Australia were commemorated by the National Health and Medical Research Council, which created the Sir Charles James Martin Overseas Biomedical Fellowships in 1951.


Personal life

Martin married Edith Cross, daughter of Alfred Cross (and aunt of the Lord of Appeal in Ordinary, Geoffrey Cross and the legal scholar Rupert Cross) in 1891. She died 2 March 1954."Charles Martin his life and letters", by Martin Gibbs, published in 2011 They had one daughter, Maisie. Martin died 15 February 1955 at Old Chesterton, Cambridge. He is buried in the Parish of the Ascension Burial Ground in Cambridge.


References


External links

* {{DEFAULTSORT:Martin, Charles James British scientists 1866 births 1955 deaths People from Hackney Central Alumni of King's College London Fellows of King's College London Academics of King's College London Royal Medal winners Alumni of Birkbeck, University of London Fellows of the Royal Society Fellows of the Royal College of Physicians Knights Bachelor Companions of the Order of St Michael and St George People from Chesterton, Cambridge People from Dalston Australian military personnel of World War I Royal Australian Army Medical Corps officers Military personnel from the London Borough of Hackney