Cefsulodin is a third-generation

cephalosporin The cephalosporins (sg. ) are a class of β-lactam antibiotics originally derived from the fungus ''Acremonium'', which was previously known as ''Cephalosporium''. Together with cephamycins, they constitute a subgroup of β-lactam antibiotics ...

antibiotic that is active against '' Pseudomonas aeruginosa'' and was discovered by Takeda Pharmaceutical Company in 1977. TAP Pharmaceuticals had a new drug application on file with FDA for cefsulodin under the brand name Cefonomil as of 1985. Cefsulodin is most commonly used in cefsulodin-irgasan-novobiocin agar to select for ''Yersinia'' microorganisms. This agar is most often used in water and beverage testing.

Susceptibility data

The following represents MIC susceptibility data for various ''P. aeruginosa'' strains: * ''Pseudomonas aeruginosa'' PA13 (resistant strain): 32 μg/ml * ''Pseudomonas aeruginosa'' (wild-type, susceptible): 4 - 8 μg/ml

References

{{CephalosporinAntiBiotics Cephalosporin antibiotics Isonicotinamides Takeda Pharmaceutical Company brands Sulfonates