Castiglia () is an Italian surname. Notable people with the surname include:
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Albert Castiglia
Albert Castiglia (born August 12, 1969) is an American blues singer, songwriter and guitarist. Castiglia has variously worked alongside Junior Wells, Sandra Hall, Aron Burton, Pinetop Perkins, Melvin Taylor, Sugar Blue, Phil Guy, Ronnie Earl, Bi ...
(born 1969), American musician
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Ferdinando Castiglia (died 1521), Italian Roman Catholic bishop
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Francesco Castiglia (1891–1973), later Frank Costello, Italian-American crime boss
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Ivan Castiglia (born 1988), Italian footballer
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Jim Castiglia (1918–2007), American football player
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Luca Castiglia (born 1989), Italian footballer
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Paul Castiglia (born 1966), American comic book writer and editor
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Vincent Castiglia (born 1982), American painter
{{surname, Castiglia
Italian-language surnames