Casticin is a methoxylated

flavonol Flavonols are a class of flavonoids that have the 3-hydroxyflavone backbone (IUPAC name: 3-hydroxy-2-phenylchromen-4-one). Their diversity stems from the different positions of the phenolic –OH groups. They are distinct from flavanols (with ...

, meaning the core flavonoid structure has methyl groups attached. Found in ''

Artemisia annua ''Artemisia annua'', also known as sweet wormwood, sweet annie, sweet sagewort, annual mugwort or annual wormwood, is a common type of wormwood native to temperate Asia, but naturalized in many countries including scattered parts of North Ameri ...

'', the flavonoid has been shown to enhance the antimalarial activity of artemisinin though casticin itself has no direct antimalarial effects. It has been shown to have anti-

mitotic Mitosis () is a part of the cell cycle in eukaryotic cells in which replicated chromosomes are separated into two new nuclei. Cell division by mitosis is an equational division which gives rise to genetically identical cells in which the t ...

activity. It is also found in ''

Vitex agnus-castus ''Vitex agnus-castus'' (also called vitex, chaste tree / chastetree, chasteberry, Abraham's balm, lilac chastetree, or monk's pepper) is a plant native of the Mediterranean region. It is one of the few temperate-zone species of ''Vitex'', which ...

''.

References

External links

* Flavones Diols {{aromatic-stub