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Caroline Hampton Halsted (November 20, 1861 – November 27, 1922) was an American nurse who became the first to use
medical glove Medical gloves are disposable gloves used during medical examinations and procedures to help prevent cross-contamination between caregivers and patients. Medical gloves are made of different polymers including latex, nitrile rubber, polyvinyl ch ...
s in the operating room.


Biography

Caroline Hampton was a member of a prominent southern U.S. family; her uncle,
Wade Hampton III Wade Hampton III (March 28, 1818April 11, 1902) was an American politician from South Carolina. He was a prominent member of one of the richest families in the antebellum Southern United States, owning thousands of acres of cotton land in Sout ...
, was a Confederate General, governor of South Carolina, and a US senator. Her mother, Sally (Baxter) Hampton died in 1862 of
tuberculosis Tuberculosis (TB), also known colloquially as the "white death", or historically as consumption, is a contagious disease usually caused by ''Mycobacterium tuberculosis'' (MTB) bacteria. Tuberculosis generally affects the lungs, but it can al ...
. Her father, Colonel Frank Hampton, died at the
Battle of Brandy Station The Battle of Brandy Station, also called the Battle of Fleetwood Hill, was the largest predominantly cavalry engagement of the American Civil War, as well as the largest ever to take place on American soil. It was fought on June 9, 1863, around ...
in early 1863 during the
American Civil War The American Civil War (April 12, 1861May 26, 1865; also known by Names of the American Civil War, other names) was a civil war in the United States between the Union (American Civil War), Union ("the North") and the Confederate States of A ...
. Their family home Millwood was burned, and Hampton was raised by three aunts, with the expectation that she would marry well, ideally to a southern plantation owner. Against her family's wishes, she went to nursing school in New York. She trained first at Mount Sinai Hospital and then at
New York Hospital Weill Cornell Medical Center (; previously known as New York Hospital, Old New York Hospital, and City Hospital) is a research hospital in New York City. It is the teaching hospital for Cornell University's medical school and is part of NewYork-P ...
, graduating in 1888. In 1889 she became chief surgical nurse at
Johns Hopkins Hospital Johns Hopkins Hospital (JHH) is the teaching hospital and biomedical research facility of Johns Hopkins School of Medicine in Baltimore, Maryland. Founded in 1889, Johns Hopkins Hospital and its school of medicine are considered to be the foundin ...
in
Baltimore Baltimore is the most populous city in the U.S. state of Maryland. With a population of 585,708 at the 2020 census and estimated at 568,271 in 2024, it is the 30th-most populous U.S. city. The Baltimore metropolitan area is the 20th-large ...
, working for
William Stewart Halsted William Stewart Halsted, M.D. (September 23, 1852 – September 7, 1922) was an American surgeon who emphasized strict aseptic technique during surgical procedures, was an early champion of newly discovered anesthetics, and introduced severa ...
.


Rubber gloves

The impetus for Hampton's use of gloves was her sensitive skin. Previously she had to wear gloves when gardening, and the procedures at the hospital caused her to develop severe
contact dermatitis Contact dermatitis is a type of acute or chronic inflammation of the skin caused by exposure to chemical or physical agents. Symptoms of contact dermatitis can include itchy or dry skin, a red rash, bumps, blisters, or swelling. These rashes ...
and painful
eczema Dermatitis is a term used for different types of skin inflammation, typically characterized by itchiness, redness and a rash. In cases of short duration, there may be small blisters, while in long-term cases the skin may become thickened ...
. Halsted, as a supporter of the
germ theory of disease The germ theory of disease is the currently accepted scientific theory for many diseases. It states that microorganisms known as pathogens or "germs" can cause disease. These small organisms, which are too small to be seen without magnification, ...
, used strict hygienic measures in his operating theater. People had to cleanse their hands using
soap Soap is a salt (chemistry), salt of a fatty acid (sometimes other carboxylic acids) used for cleaning and lubricating products as well as other applications. In a domestic setting, soaps, specifically "toilet soaps", are surfactants usually u ...
, followed by a caustic solution of
potassium permanganate Potassium permanganate is an inorganic compound with the chemical formula KMnO4. It is a purplish-black crystalline salt, which dissolves in water as K+ and ions to give an intensely pink to purple solution. Potassium permanganate is widely us ...
, a hot
oxalic acid Oxalic acid is an organic acid with the systematic name ethanedioic acid and chemical formula , also written as or or . It is the simplest dicarboxylic acid. It is a white crystalline solid that forms a colorless solution in water. Its name i ...
bath, and a mercury chloride compound. In the winter of 1889 Caroline Hampton informed Halsted of her intention to resign due to the effects on her hands. Halsted considered Hampton an “unusually efficient” operating room assistant. He suggested that she try coating her hands in a gelatinous substance called
collodion Collodion is a flammable, syrupy solution of nitrocellulose in Diethyl ether, ether and Alcohol (chemistry), alcohol. There are two basic types: flexible and non-flexible. The flexible type is often used as a surgical dressing or to hold dressings ...
. It hardened but tended to crack. Next Halsted sent plaster casts of Caroline's hands to the Goodyear Rubber Company of New York, and ordered two pairs of bespoke rubber gloves to cover her hands and forearms. The resulting gloves were thin, flexible, and reusable, and protected Hampton's hands. Halsted was surprised to return from an extended vacation and find that others in the operating room had also adopted rubber gloves, following Caroline's example. The gloves protected the medical staff's hands, and surgical assistants reported that the textured surface of the gloves made it easier to hold onto slippery surgical instruments. That they also protected patients was discovered by one of Halsted's surgical residents, Joseph Colt Bloodgood. In 1899, Bloodgood published results showing that use of gloves during surgery reduced postsurgical infection rates from 17% to less than 2%, a staggering effect.


Marriage

Caroline Hampton and William Halsted were married on June 4, 1890, at Trinity Episcopal Church,
Columbia, South Carolina Columbia is the List of capitals in the United States, capital city of the U.S. state of South Carolina. With a population of 136,632 at the 2020 United States census, 2020 census, it is List of municipalities in South Carolina, the second-mo ...
. Caroline, as a married woman, was required to resign from her job at the hospital. Caroline ran their household during the winter, and their farm High Hampton in
North Carolina North Carolina ( ) is a U.S. state, state in the Southeastern United States, Southeastern region of the United States. It is bordered by Virginia to the north, the Atlantic Ocean to the east, South Carolina to the south, Georgia (U.S. stat ...
during the summer. Caroline suffered later in life from
migraines Migraine (, ) is a complex neurological disorder characterized by episodes of moderate-to-severe headache, most often unilateral and generally associated with nausea, and light and sound sensitivity. Other characterizing symptoms may includ ...
, and it is suspected that she, as well as her husband, may have used
morphine Morphine, formerly also called morphia, is an opiate that is found naturally in opium, a dark brown resin produced by drying the latex of opium poppies (''Papaver somniferum''). It is mainly used as an analgesic (pain medication). There are ...
. Both were known for their eccentricity. Anecdotes about their modes of entertaining, attachment to pets and marital life amused local society.


References


External links

* {{DEFAULTSORT:Hampton, Caroline American nurses American women nurses Family of Wade Hampton I 1861 births 1922 deaths