Carnitine O-palmitoyltransferase (also called carnitine palmitoyltransferase) is a
mitochondrial
A mitochondrion () is an organelle found in the cells of most eukaryotes, such as animals, plants and fungi. Mitochondria have a double membrane structure and use aerobic respiration to generate adenosine triphosphate (ATP), which is used ...
transferase
In biochemistry, a transferase is any one of a class of enzymes that catalyse the transfer of specific functional groups (e.g. a methyl or glycosyl group) from one molecule (called the donor) to another (called the acceptor). They are involved ...
enzyme
An enzyme () is a protein that acts as a biological catalyst by accelerating chemical reactions. The molecules upon which enzymes may act are called substrate (chemistry), substrates, and the enzyme converts the substrates into different mol ...
() involved in the metabolism of
palmitoylcarnitine into
palmitoyl-CoA. A related transferase is carnitine acyltransferase.
Molecules
Image:Palmitoylcarnitine.PNG , Palmitoylcarnitine
Image:Palmitoyl coenzyme A.svg, Palmitoyl CoA
Pathway
Human forms
There are four different forms of CPT in humans:
*
CPT1A – associated with
Carnitine palmitoyltransferase I deficiency
*
CPT1B
*
CPT1C
*
CPT2 – associated with
carnitine palmitoyltransferase II deficiency
See also
*
References
External links
* – Acyltransferases ChoActase / COT / CPT family in
PROSITE
Choline/Carnitine o-acyltransferase familyin
Pfam
*
*
Integral membrane proteins
EC 2.3.1
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