Cannabicitran (CBTC) is a

phytocannabinoid Cannabinoids () are several structural classes of compounds found primarily in the ''Cannabis'' plant or as synthetic compounds. The most notable cannabinoid is the phytocannabinoid tetrahydrocannabinol (THC) (delta-9-THC), the primary psychoac ...

first isolated in 1974 as a trace component of ''

Cannabis sativa ''Cannabis sativa'' is an annual Herbaceous plant, herbaceous flowering plant. The species was first classified by Carl Linnaeus in 1753. The specific epithet ''Sativum, sativa'' means 'cultivated'. Indigenous to East Asia, Eastern Asia, the pla ...

''. Structurally related compounds can be found in some other plants. It is not psychoactive, but was found to reduce

intraocular pressure Intraocular pressure (IOP) is the fluid pressure inside the eye. Tonometry is the method eye care professionals use to determine this. IOP is an important aspect in the evaluation of patients at risk of glaucoma. Most tonometers are calibrated t ...

in tests on rabbits, which may reflect agonist activity at the

NAGly receptor ''N''-Arachidonyl glycine receptor (NAGly receptor), also known as G protein-coupled receptor 18 (GPR18), is a protein that in humans is encoded by the ''GPR18'' gene. Along with the other previously orphan receptors GPR55 and GPR119, GPR18 has ...

(formally GPR18) that is known to be a target of many structurally related cannabinoids.

References

Benzochromenes Phytocannabinoids Heterocyclic compounds with 4 rings Oxygen heterocycles {{cannabinoid-stub

See also

References