Caecum Praegrande
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The cecum ( caecum, ; plural ceca or caeca, ) is a pouch within the
peritoneum The peritoneum is the serous membrane forming the lining of the abdominal cavity or coelom in amniotes and some invertebrates, such as annelids. It covers most of the intra-abdominal (or coelomic) organs, and is composed of a layer of mesotheli ...
that is considered to be the beginning of the
large intestine The large intestine, also known as the large bowel, is the last part of the gastrointestinal tract and of the Digestion, digestive system in tetrapods. Water is absorbed here and the remaining waste material is stored in the rectum as feces befor ...
. It is typically located on the right side of the body (the same side of the body as the
appendix Appendix (: appendices or appendixes) may refer to: __NOTOC__ In documents * Addendum, an addition made to a document by its author after its initial printing or publication * Bibliography, a systematic list of books and other works * Index (publis ...
, to which it is joined). The term stems from the
Latin Latin ( or ) is a classical language belonging to the Italic languages, Italic branch of the Indo-European languages. Latin was originally spoken by the Latins (Italic tribe), Latins in Latium (now known as Lazio), the lower Tiber area aroun ...
'' caecus'', meaning " blind". It receives
chyme Chyme or chymus (; ) is the semi-fluid mass of partly digested food that is expelled by the stomach, through the pyloric valve, into the duodenum (the beginning of the small intestine). Chyme results from the mechanical and chemical breakdown ...
from the
ileum The ileum () is the final section of the small intestine in most higher vertebrates, including mammals, reptiles, and birds. In fish, the divisions of the small intestine are not as clear and the terms posterior intestine or distal intestine may ...
, and connects to the
ascending colon In the anatomy of humans and homologous primates, the ascending colon is the part of the colon located between the cecum and the transverse colon. Characteristics and structure The ascending colon is smaller in calibre than the cecum from wh ...
of the
large intestine The large intestine, also known as the large bowel, is the last part of the gastrointestinal tract and of the Digestion, digestive system in tetrapods. Water is absorbed here and the remaining waste material is stored in the rectum as feces befor ...
. It is separated from the ileum by the ileocecal valve (ICV), also called Bauhin's valve. It is also separated from the Large intestine#Structure, colon by the cecocolic junction. While the cecum is usually intraperitoneal, the ascending colon is Retroperitoneal space, retroperitoneal. In herbivores, the cecum stores food material where bacteria are able to break down the cellulose. In humans, the cecum is involved in absorption of Salt (chemistry), salts and Electrolyte, electrolytes and lubricates the solid waste that passes into the large intestine.


Structure


Development

The cecum and appendix are derived from the bud of cecum that forms during week six in the midgut next to the apex of the umbilical herniation. Specifically, the cecum and appendix are formed by the enlargement of the postarterial segment of the midgut loop. The proximal part of the bud grows rapidly to form the cecum. The lateral wall of the cecum grows much more rapidly than the medial wall, with the result that the point of attachment of the
appendix Appendix (: appendices or appendixes) may refer to: __NOTOC__ In documents * Addendum, an addition made to a document by its author after its initial printing or publication * Bibliography, a systematic list of books and other works * Index (publis ...
comes to lie on the medial side. The cecum's position changes after the midgut rotates and the ascending colon elongates, and the accumulation of meconium inside the cecum may result in the latter's increased diameter.


History


Etymology

The term ''cecum'' comes from Latin ''(intestinum) caecum'', literally 'blind intestine', in the sense 'blind gut' or 'cul de sac'. It is a direct translation from Ancient Greek () (). Thus the inflammation of the cecum is called typhlitis. In dissections by the Ancient Greece, Greek Greek philosophy, philosophers, the connection between the
ileum The ileum () is the final section of the small intestine in most higher vertebrates, including mammals, reptiles, and birds. In fish, the divisions of the small intestine are not as clear and the terms posterior intestine or distal intestine may ...
of the small intestine and the cecum was not fully understood. Most of the studies of the Gastrointestinal tract, digestive tract were done on animals and the results were compared to human human anatomy, structures. The junction between the small intestine and the colon, called the ileocecal valve, is so small in some animals that it was not considered to be a connection between the small and large intestines. During a dissection, the colon could be traced from the rectum, to the sigmoid colon, through the descending colon, descending, transverse colon, transverse, and ascending colon, ascending sections. The cecum is an end point for the colon with a dead-end portion terminating with the
appendix Appendix (: appendices or appendixes) may refer to: __NOTOC__ In documents * Addendum, an addition made to a document by its author after its initial printing or publication * Bibliography, a systematic list of books and other works * Index (publis ...
. The connection between the end of the small intestine (ileum) and the start (as viewed from the perspective of food being processed) of the colon (cecum) is now clearly understood, and is called the ileocecal orifice. The connection between the end of the cecum and the beginning of the ascending colon is called the cecocolic orifice.


Clinical significance

A cecal carcinoid tumor is a carcinoid tumor of the cecum. An appendiceal carcinoid tumor (a carcinoid tumor of the appendix) is sometimes found next to a cecal carcinoid. Neutropenic enterocolitis (typhlitis) is the condition of inflammation of the cecum, primarily caused by bacterial infections. Over 99% of the bacteria in the gut are anaerobes,University of Glasgow. 2005.
The normal gut flora.
Available through web archive. Accessed May 22, 2008
but in the cecum, aerobic bacteria reach high densities.


Other animals

A cecum is present in most amniote species, and also in lungfish, but not in any living species of amphibian. In reptiles, it is usually a single median structure, arising from the dorsal side of the large intestine. Birds typically have two paired ceca, as do, unlike other mammals, hyraxes. Parrots do not have ceca. Most mammalian herbivores have a relatively large cecum. In many species, it is considerably wider than the colon. For some herbivores such as lagomorpha, lagomorphs (rabbits, hares, pikas), easily digestible food is processed in the gastrointestinal tract and expelled as regular feces. But in order to get nutrients out of hard to digest fiber, lagomorphs ferment fiber in the cecum and then expel the contents as cecotropes, which are reingested (cecotrophy). The cecotropes are then absorbed in the small intestine to utilize the nutrients. In contrast, obligate carnivores, whose diets contain little or no plant matter, have a reduced cecum, which is often partially or wholly replaced by the
appendix Appendix (: appendices or appendixes) may refer to: __NOTOC__ In documents * Addendum, an addition made to a document by its author after its initial printing or publication * Bibliography, a systematic list of books and other works * Index (publis ...
. Mammalian species which do not develop a cecum include raccoons, bears, and the red panda. Many fish have a number of small outpockets, called ''pyloric ceca'', along their intestine; despite the name, they are not homology (biology), homologous with the cecum of amniotes – their purpose is to increase the overall area of the digestive epithelium. Some invertebrates, such as squid, may also have structures with the same name, but these have no relationship with those of vertebrates.


Gallery

File:Blausen 0604 LargeIntestine2.png, Illustration of the large intestine File:Cecum and ileum.JPG, Cecum and ileum File:Ileo-cecal valve.JPG, Ileo-cecal valve File:Cecum and ileocecal valve.JPG, Cecum File:Gray536.png, Arteries of cecum and Appendix (anatomy), vermiform process File:Gray1044.png, Inferior ileocecal fossa File:Ileocecal valve.jpg, Colonoscopy, Endoscopic image of cecum with arrow pointing to ileocecal valve in foreground


See also

* McBurney's point


References


External links

* —"Abdominal organs in situ." * —"The larger intestine." * —"The cecum with the distal portion of the ileum." * —"Incisions of the Cecum" *
Photo at mgccc.cc.ms.us

Video clip of worms in the Cecum
() {{Authority control Digestive system Latin words and phrases