CUMYL-THPINACA (also known as SGT-42) is an
indazole-3-carboxamide based
synthetic cannabinoid
Synthetic cannabinoids, or neocannabinoids, are a class of designer drug molecules that Binding affinity, bind to the same receptors to which cannabinoids (Tetrahydrocannabinol, THC, Cannabidiol, CBD and many others) in cannabis plants attach. Th ...
.
CUMYL-THPINACA acts as a potent
agonist
An agonist is a chemical that activates a Receptor (biochemistry), receptor to produce a biological response. Receptors are Cell (biology), cellular proteins whose activation causes the cell to modify what it is currently doing. In contrast, an R ...
for the
cannabinoid receptors, with approximately 6x selectivity for
CB1, having an EC
50 of 0.1nM for human
CB1 receptors and 0.59nM for human
CB2 receptors.
Legal status
Sweden's public health agency suggested to classify CUMYL-THPINACA as hazardous substance on November 10, 2014.
As of October 2015 CUMYL-THPINACA is a controlled substance in China.
See also
*
5F-CUMYL-PINACA
*
5F-SDB-006
*
ADAMANTYL-THPINACA
*
CUMYL-4CN-BINACA
*
CUMYL-CBMINACA
*
CUMYL-PICA
*
CUMYL-PINACA
*
SDB-006
*
NNE1
References
Cannabinoids
Designer drugs
Indazolecarboxamides
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