CM-4620 is a drug which acts as a selective inhibitor of the

calcium channel A calcium channel is an ion channel which shows selective permeability to calcium ions. It is sometimes synonymous with voltage-gated calcium channel, which are a type of calcium channel regulated by changes in membrane potential. Some calcium chan ...

ORAI1 Calcium release-activated calcium channel protein 1 is a calcium selective ion channel that in humans is encoded by the ''ORAI1'' gene. Orai channels play an important role in the activation of T-lymphocytes. The loss of function mutation of Orai ...

. It has

antiinflammatory Anti-inflammatory is the property of a substance or treatment that reduces inflammation, fever or swelling. Anti-inflammatory drugs, also called anti-inflammatories, make up about half of analgesics. These drugs reduce pain by inhibiting mechani ...

effects and is being researched for the treatment of

pancreatitis Pancreatitis is a condition characterized by inflammation of the pancreas. The pancreas is a large organ behind the stomach that produces digestive enzymes and a number of hormone A hormone (from the Ancient Greek, Greek participle , "se ...

References

{{pharm-stub Anti-inflammatory agents Calcium channel blockers Aminopyrimidines Methylenedioxyphenethylamines