Claudin-15 is a

protein Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residues. Proteins perform a vast array of functions within organisms, including catalysing metabolic reactions, DNA replication, respon ...

that in humans is encoded by the ''CLDN15''

gene In biology, the word gene (from , ; "... Wilhelm Johannsen coined the word gene to describe the Mendelian units of heredity..." meaning ''generation'' or ''birth'' or ''gender'') can have several different meanings. The Mendelian gene is a b ...

. It belongs to the group of

claudin Claudins are a family of proteins which, along with occludin, are the most important components of the tight junctions ( zonulae occludentes). Tight junctions establish the paracellular barrier that controls the flow of molecules in the intercel ...

s. Among its related pathways are Blood-Brain Barrier and Immune Cell Transmigration: VCAM-1/CD106

Signaling Pathways Signal transduction is the process by which a chemical or physical signal is transmitted through a cell as a series of molecular events, most commonly protein phosphorylation catalyzed by protein kinases, which ultimately results in a cellular ...

and Tight junction. GO annotations related to this gene include ''identical protein binding'' and ''structural molecule activity''. An important paralog of this gene is

CLDN10 Claudin-10 is a protein that in humans is encoded by the ''CLDN10'' gene. It belongs to the group of claudins. This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. T ...

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