Neural cell adhesion molecule L1-like protein also known as close homolog of L1 (CHL1) is a
protein
Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residues. Proteins perform a vast array of functions within organisms, including catalysing metabolic reactions, DNA replication, respon ...
that in humans is encoded by the ''CHL1''
gene
In biology, the word gene (from , ; "... Wilhelm Johannsen coined the word gene to describe the Mendelian units of heredity..." meaning ''generation'' or ''birth'' or ''gender'') can have several different meanings. The Mendelian gene is a b ...
.
CHL1 is a
cell adhesion molecule
Cell adhesion molecules (CAMs) are a subset of cell surface proteins that are involved in the binding of cells with other cells or with the extracellular matrix (ECM), in a process called cell adhesion. In essence, CAMs help cells stick to each ...
closely related to the
L1. In melanocytic cells CHL1 gene expression may be regulated by
MITF,
and can act as a
helicase protein during the
interphase stage of
mitosis.
The protein, however, has dynamic localisation, meaning that it has not only multiple roles in the cell, but also various locations.
References
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