CGS-9896
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CGS-9896 is an
anxiolytic An anxiolytic (; also antipanic or anti-anxiety agent) is a medication or other intervention that reduces anxiety. This effect is in contrast to anxiogenic agents which increase anxiety. Anxiolytic medications are used for the treatment of anxie ...
drug used in scientific research. It has similar effects to
benzodiazepine Benzodiazepines (BZD, BDZ, BZs), colloquially known as "benzos", are a class of central nervous system (CNS) depressant, depressant drugs whose core chemical structure is the fusion of a benzene ring and a diazepine ring. They are prescribed t ...
drugs but is structurally distinct and so is classed as a
nonbenzodiazepine Nonbenzodiazepines (), sometimes referred to colloquially as Z-drugs (as many of their names begin with the letter "z"), are a class of psychoactive, depressant, sedative, hypnotic, anxiolytic drugs that are benzodiazepine-like in uses, such as f ...
anxiolytic. CGS-9896 is a benzodiazepine receptor partial agonist which produces long-lasting anxiolytic and
anticonvulsant Anticonvulsants (also known as antiepileptic drugs, antiseizure drugs, or anti-seizure medications (ASM)) are a diverse group of pharmacological agents used in the treatment of epileptic seizures. Anticonvulsants are also used in the treatme ...
effects in animal studies but does not produce sedative effects. It also increases appetite, and reduces the development of gastrointestinal ulcers following chronic stress.


References

Anxiolytics Pyrazoloquinolines Lactams 4-Chlorophenyl compounds GABAA receptor positive allosteric modulators Experimental drugs {{anxiolytic-stub