CGS-12066A is a

drug A drug is any chemical substance other than a nutrient or an essential dietary ingredient, which, when administered to a living organism, produces a biological effect. Consumption of drugs can be via insufflation (medicine), inhalation, drug i ...

which acts as a potent and selective

agonist An agonist is a chemical that activates a Receptor (biochemistry), receptor to produce a biological response. Receptors are Cell (biology), cellular proteins whose activation causes the cell to modify what it is currently doing. In contrast, an R ...

for the 5-HT_1B

receptor Receptor may refer to: * Sensory receptor, in physiology, any neurite structure that, on receiving environmental stimuli, produces an informative nerve impulse *Receptor (biochemistry), in biochemistry, a protein molecule that receives and respond ...

with lower affinity for the three 5-HT₂ receptor subtypes. It is used for studying the role of the 5-HT_1B receptor in various processes including perception of pain and the sleep-wake cycle.

References

Serotonin receptor agonists Trifluoromethyl compounds 4-Methylpiperazin-1-yl compounds Quinoxalines {{nervous-system-drug-stub