Butalamine is a

vasodilator Vasodilation is the widening of blood vessels. It results from relaxation of smooth muscle cells within the vessel walls, in particular in the large veins, large arteries, and smaller arterioles. The process is the opposite of vasoconstriction ...

Synthesis

Check with

imolamine Imolamine (INN, BAN; brand names Angolon, Angoril, Circuline, Irri-Cor, Irrigor, Coremax) is a coronary vasodilator which is used in the treatment of angina pectoris and as a local anesthetic. Use patents:Anne Rolland, (1986 to Laboratoires Al ...

(alternate nitrogen reacts) Butalamine synthesis

The halogenation of benzamidoxime

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22-31-1(1) with chlorine and subsequent reaction with

cyanamide Cyanamide is an organic compound with the formula C N2 H2. This white solid is widely used in agriculture and the production of pharmaceuticals and other organic compounds. It is also used as an alcohol-deterrent drug. The molecule features a ...

(3) gives 5-amino-3-phenyl-1,2,4-oxadiazole 663-37-4(4). Base catalyzed alkylation with dibutylaminoethyl chloride

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(5) completes the synthesis of butalamine (6).

References

Vasodilators Oxadiazoles {{cardiovascular-drug-stub