Butalamine is a

vasodilator Vasodilation, also known as vasorelaxation, is the widening of blood vessels. It results from relaxation of smooth muscle cells within the vessel walls, in particular in the large veins, large arteries, and smaller arterioles. Blood vessel wal ...

Synthesis

The reaction of benzamidoxime (1) with chlorine and subsequent reaction with

cyanamide Cyanamide is an organic compound with the formula C N2 H2. This white solid is widely used in agriculture and the production of pharmaceuticals and other organic compounds. It is also used as an alcohol-deterrent drug. The molecule features a ...

(3) gives 5-amino-3-phenyl-1,2,4-oxadiazole (4).Aron-Samuel Jan Marcel Didier, Sterne Jean Jacques, (1967 to). Base catalyzed

alkylation Alkylation is a chemical reaction that entails transfer of an alkyl group. The alkyl group may be transferred as an alkyl carbocation, a free radical, a carbanion, or a carbene (or their equivalents). Alkylating agents are reagents for effecting al ...

with dibutylaminoethyl chloride (5) completes the synthesis of butalamine (6). : Butalamine synthesis

References

Vasodilators Oxadiazoles {{cardiovascular-drug-stub