Bruceolide is a

quassinoid Quassinoids are degraded triterpene lactones (similar to limonoids) of the Simaroubaceae plant family grouped into C-18, C-19, C-20, C-22 and C-25 types. The prototypical member of the group, quassin, was first described in the 19th century fr ...

that has been isolated from ''

Bischofia javanica ''Bischofia javanica'', or bishop wood, is a plant species of the family Phyllanthaceae. It and the related '' Bischofia polycarpa'' are the only two members of genus '' Bischofia'' and tribe Bischofieae. These species are distributed throughout ...

''. Synthetic

derivatives The derivative of a function is the rate of change of the function's output relative to its input value. Derivative may also refer to: In mathematics and economics *Brzozowski derivative in the theory of formal languages *Formal derivative, an ...

have shown ''

in vitro ''In vitro'' (meaning in glass, or ''in the glass'') studies are performed with microorganisms, cells, or biological molecules outside their normal biological context. Colloquially called "test-tube experiments", these studies in biology and ...

'' antimalarial activity.

References

Quassinoids {{organic-compound-stub