Brian McArdle (9 April 1911 – 1 August 2002) was a British medical doctor and researcher, best known for first describing

glycogen storage disease type V Glycogen storage disease type V (GSD5, GSD-V), also known as McArdle's disease, is a metabolic disorder, one of the metabolic myopathies, more specifically a muscle glycogen storage disease, caused by a deficiency of myophosphorylase. Its incid ...

in his 1951 paper entitled ''Myopathy due to a defect in muscle glycogen breakdown'', at

Guy's Hospital Guy's Hospital is an NHS hospital founded by philanthropist Thomas Guy in 1721, located in the borough of Southwark in central London. It is part of Guy's and St Thomas' NHS Foundation Trust and one of the institutions that comprise the Kin ...

.'' The paper described a 30 year old man with a history of exertional

muscle pain Myalgia or muscle pain is a painful sensation evolving from muscle tissue. It is a symptom of many diseases. The most common cause of acute myalgia is the overuse of a muscle or group of muscles; another likely cause is viral infection, espec ...

and stiffnesssymptoms that previous doctors had dismissed as psychological but which are now attributed to glycogen storage disease type V. Since then, the molecular and genetic basis of the disease has been identified. Besides the disease's scientific name, it is also named eponymously as ''McArdle's disease''.

References

20th-century British medical doctors 1911 births 2002 deaths {{UK-med-bio-stub