Bragg Curve
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The Bragg peak is a pronounced peak on the Bragg curve which plots the energy loss of
ionizing radiation Ionizing (ionising) radiation, including Radioactive decay, nuclear radiation, consists of subatomic particles or electromagnetic waves that have enough energy per individual photon or particle to ionization, ionize atoms or molecules by detaching ...
during its travel through matter. For
proton A proton is a stable subatomic particle, symbol , Hydron (chemistry), H+, or 1H+ with a positive electric charge of +1 ''e'' (elementary charge). Its mass is slightly less than the mass of a neutron and approximately times the mass of an e ...
s, α-rays, and other ion rays, the peak occurs immediately before the particles come to rest. It is named after
William Henry Bragg Sir William Henry Bragg (2 July 1862 – 12 March 1942) was an English physicist and X-ray crystallographer who uniquelyThis is still a unique accomplishment, because no other parent-child combination has yet shared a Nobel Prize (in any fiel ...
, who discovered it in 1903 using alpha particles from radium, and wrote the first empirical formula for ionization energy loss per distance with Richard Kleeman. When a fast
charged particle In physics, a charged particle is a particle with an electric charge. For example, some elementary particles, like the electron or quarks are charged. Some composite particles like protons are charged particles. An ion, such as a molecule or atom ...
moves through matter, it
ionizes Ionization or ionisation is the process by which an atom or a molecule acquires a negative or positive charge by gaining or losing electrons, often in conjunction with other chemical changes. The resulting electrically charged atom or molecule is ...
atoms of the material and deposits a
dose Dose or Dosage may refer to: Music * ''Dose'' (Gov't Mule album), 1998 * ''Dose'' (Latin Playboys album) * ''Dosage'' (album), by the band Collective Soul * "Dose" (song), a 2018 song by Ciara * "Dose", song by Filter from the album '' Short ...
along its path. A peak occurs because the interaction
cross section Cross section may refer to: * Cross section (geometry) ** Cross-sectional views in architecture and engineering 3D *Cross section (geology) * Cross section (electronics) * Radar cross section, measure of detectability * Cross section (physics) **A ...
increases as the charged particle's energy decreases. Energy lost by charged particles is inversely proportional to the square of their velocity, which explains the peak occurring just before the particle comes to a complete stop. In the upper figure, it is the peak for alpha particles of 5.49 MeV moving through air. In the lower figure, it is the narrow peak of the "native" proton beam curve which is produced by a
particle accelerator A particle accelerator is a machine that uses electromagnetic fields to propel electric charge, charged particles to very high speeds and energies to contain them in well-defined particle beam, beams. Small accelerators are used for fundamental ...
of 250
MeV In physics, an electronvolt (symbol eV), also written electron-volt and electron volt, is the measure of an amount of kinetic energy gained by a single electron accelerating through an electric potential difference of one volt in vacuum. When us ...
. The figure also shows the absorption of a beam of energetic
photon A photon () is an elementary particle that is a quantum of the electromagnetic field, including electromagnetic radiation such as light and radio waves, and the force carrier for the electromagnetic force. Photons are massless particles that can ...
s (
X-ray An X-ray (also known in many languages as Röntgen radiation) is a form of high-energy electromagnetic radiation with a wavelength shorter than those of ultraviolet rays and longer than those of gamma rays. Roughly, X-rays have a wavelength ran ...
s) which is entirely different in nature; the curve is mainly
exponential Exponential may refer to any of several mathematical topics related to exponentiation, including: * Exponential function, also: **Matrix exponential, the matrix analogue to the above *Exponential decay, decrease at a rate proportional to value * Ex ...
. This characteristic of proton beams was first recommended for use in cancer therapy by Robert R. Wilson in his 1946 article, Radiological Use of Fast Protons. Wilson studied how the depth of proton beam penetration could be controlled by the energy of the protons. This phenomenon is exploited in
particle therapy Particle therapy is a form of external beam radiotherapy using beams of energetic neutrons, protons, or other heavier positive ions for cancer treatment. The most common type of particle therapy as of August 2021 is proton therapy. In contrast ...
of cancer, specifically in proton therapy, to concentrate the effect of light
ion beam An ion beam is a beam of ions, a type of charged particle beam. Ion beams have many uses in electronics manufacturing (principally ion implantation) and other industries. There are many ion beam sources, some derived from the mercury vapor ...
s on the
tumor A neoplasm () is a type of abnormal and excessive growth of tissue. The process that occurs to form or produce a neoplasm is called neoplasia. The growth of a neoplasm is uncoordinated with that of the normal surrounding tissue, and persists ...
being treated while minimizing the effect on the surrounding healthy tissue. The blue curve in the figure ("modified
proton beam A charged particle beam is a spatially localized group of electrically charged particles that have approximately the same position, kinetic energy (resulting in the same velocity), and direction. The kinetic energies of the particles are much la ...
") shows how the originally monoenergetic proton beam with the sharp peak is widened by increasing the range of energies, so that a larger tumor volume can be treated. The plateau created by modifying the proton beam is referred to as the spread out Bragg Peak, or SOBP, which allows the treatment to conform to not only larger tumors, but to more specific 3D shapes. This can be achieved by using variable thickness attenuators like spinning wedges. Momentum cooling in cyclotron-based proton therapy facilities enables a sharper distal fall-off of the Bragg peak and the attainment of high dose rates. As shown in the plots above, there is a limited range for the particles in a material. The Bragg–Kleeman rule is a way to estimate a particle's
range Range may refer to: Geography * Range (geographic), a chain of hills or mountains; a somewhat linear, complex mountainous or hilly area (cordillera, sierra) ** Mountain range, a group of mountains bordered by lowlands * Range, a term used to i ...
in a medium, serving as a tool in particle detection and
dosimetry Radiation dosimetry in the fields of health physics and radiation protection is the measurement, calculation and assessment of the ionizing radiation dose absorbed by an object, usually the human body. This applies both internally, due to ingest ...
. The basic form of the rule is: :\frac = \frac where ''R''1 and ''R''2 are the ranges of two particles, ''ρ''1 and ''ρ''2 are the
densities Density (volumetric mass density or specific mass) is the ratio of a substance's mass to its volume. The symbol most often used for density is ''ρ'' (the lower case Greek letter rho), although the Latin letter ''D'' (or ''d'') can also be use ...
of the media they traverse, and ''A''1 and ''A''2 are the atomic weights of the particles.


See also

*
Stopping power (particle radiation) In nuclear and materials physics, stopping power is the retarding force acting on charged particles, typically alpha and beta particles, due to interaction with matter, resulting in loss of particle kinetic energy. Stopping power is also inter ...
*
Bremsstrahlung In particle physics, bremsstrahlung (; ; ) is electromagnetic radiation produced by the deceleration of a charged particle when deflected by another charged particle, typically an electron by an atomic nucleus. The moving particle loses kinetic ...
*
Linear energy transfer In dosimetry, linear energy transfer (LET) is the amount of energy that an ionizing particle transfers to the material traversed per unit distance. It describes the action of radiation into matter. It is identical to the retarding force acting o ...
*
Proton therapy In medicine, proton therapy, or proton radiotherapy, is a type of particle therapy that uses a beam of protons to irradiate diseased tissue, most often to treat cancer. The chief advantage of proton therapy over other types of external beam ...


References


External links

* * * * * {{DEFAULTSORT:Bragg Peak Ionizing radiation Experimental particle physics Radiation therapy