Borage ( or ; ''Borago officinalis''), also known as starflower, is an annual

herb Herbs are a widely distributed and widespread group of plants, excluding vegetables, with savory or aromatic properties that are used for flavoring and garnishing food, for medicinal purposes, or for fragrances. Culinary use typically distingu ...

in the

flowering plant Flowering plants are plants that bear flowers and fruits, and form the clade Angiospermae (). The term angiosperm is derived from the Ancient Greek, Greek words (; 'container, vessel') and (; 'seed'), meaning that the seeds are enclosed with ...

family

Boraginaceae Boraginaceae, the Borago, borage or forget-me-not family, includes about 2,000 species of shrubs, trees, and herbs in 146 to 154 genus, genera with a worldwide distribution. The APG IV system from 2016 classifies the Boraginaceae as single famil ...

native to the Mediterranean region. Although the plant contains small amounts of

pyrrolizidine alkaloid Pyrrolizidine alkaloids (PAs), sometimes referred to as necine bases, are a group of naturally occurring alkaloids based on the structure of pyrrolizidine. Their use dates back centuries and is intertwined with the discovery, understanding, and e ...

s, some parts are edible and its seeds provide oil. Borage

Description

''B. officinalis'' grows to a height of , and is bristly or hairy all over the stems and

leaves A leaf (: leaves) is a principal appendage of the stem of a vascular plant, usually borne laterally above ground and specialized for photosynthesis. Leaves are collectively called foliage, as in "autumn foliage", while the leaves, stem, ...

; the leaves are

alternate Alternative or alternate may refer to: Arts, entertainment and media * Alternative (''Kamen Rider''), a character in the Japanese TV series ''Kamen Rider Ryuki'' * Alternative comics, or independent comics are an alternative to mainstream superh ...

simple Simple or SIMPLE may refer to: *Simplicity, the state or quality of being simple Arts and entertainment * ''Simple'' (album), by Andy Yorke, 2008, and its title track * "Simple" (Florida Georgia Line song), 2018 * "Simple", a song by John ...

, and long. The flowers are complete, perfect with five narrow, triangular-pointed

petals Petals are modified leaves that form an inner whorl surrounding the reproductive parts of flowers. They are often brightly coloured or unusually shaped to attract pollinators. All of the petals of a flower are collectively known as the ''coroll ...

. Flowers are most often blue, although pink flowers are sometimes observed. White-flowered types are also cultivated. The blue flower is genetically dominant over the white flower. The flowers arise along scorpioid cymes to form large floral displays with multiple flowers blooming simultaneously, suggesting that borage has a high degree of

geitonogamy Geitonogamy (from Greek ''geiton'' (γείτων) = neighbor + ''gamein'' (γαμεῖν) = to marry) is a type of self-pollination. Geitonogamous pollination is sometimes distinguished from the fertilizations that can result from it, geitonogamy. ...

(intraplant pollination). It has an indeterminate growth habit. In temperate climates such as in the UK, its flowering season is relatively long, from June to September. In milder climates, borage blooms continuously for most of the year. It can be invasive.

Chemistry

The seeds consist of 26–38% borage seed oil, of which 17–28% is gamma-linolenic acid (GLA, an

omega-6 fatty acid Omega−6 fatty acids (also referred to as ω−6 fatty acids or ''n''−6 fatty acids) are a family of polyunsaturated fatty acids (PUFA) that share a final carbon-carbon double bond in the ''n''−6 position, that is, the sixth bond, counti ...

), making borage seed oil the richest known source of GLA. The oil also contains the

fatty acid In chemistry, in particular in biochemistry, a fatty acid is a carboxylic acid with an aliphatic chain, which is either saturated and unsaturated compounds#Organic chemistry, saturated or unsaturated. Most naturally occurring fatty acids have an ...

palmitic acid Palmitic acid (hexadecanoic acid in IUPAC nomenclature) is a fatty acid with a 16-carbon chain. It is the most common saturated fatty acid found in animals, plants and microorganisms.Gunstone, F. D., John L. Harwood, and Albert J. Dijkstra. The ...

(10–11%),

stearic acid Stearic acid ( , ) is a saturated fatty acid with an 18-carbon chain. The IUPAC name is octadecanoic acid. It is a soft waxy solid with the formula . The triglyceride derived from three molecules of stearic acid is called stearin. Stearic acid ...

(3.5–4.5%),

oleic acid Oleic acid is a fatty acid that occurs naturally in various animal and vegetable fats and oils. It is an odorless, colorless oil, although commercial samples may be yellowish due to the presence of impurities. In chemical terms, oleic acid is cl ...

(16–20%),

linoleic acid Linoleic acid (LA) is an organic compound with the formula . Both alkene groups () are ''cis''. It is a fatty acid sometimes denoted 18:2 (n−6) or 18:2 ''cis''-9,12. A linoleate is a salt or ester of this acid. Linoleic acid is a polyunsat ...

(35–38%), eicosenoic acid (3.5–5.5%),

erucic acid Erucic acid is a monounsaturated omega-9 fatty acid, denoted 22:1ω9. It has the chemical formula: . It is prevalent in wallflower seed and other plants in the family Brassicaceae, with a reported content of 20 to 54% in high erucic acid rapese ...

(1.5–3.5%), and nervonic acid (1.5%). Healthy adults typically produce ample GLA from dietary

, but borage seed oil is often marketed as a GLA supplement, under the names "starflower oil" or "borage oil". The leaves contain small amounts (2–10 ppm in the dried herb) of the liver-toxic

pyrrolizidine alkaloids Pyrrolizidine alkaloids (PAs), sometimes referred to as necine bases, are a group of naturally occurring alkaloids based on the structure of pyrrolizidine. Their use dates back centuries and is intertwined with the discovery, understanding, and ...

(PA) intermedine, lycopsamine, amabiline, and supinine and the nontoxic saturated PA thesinine. PAs are also present in borage seed oil, but may be removed by processing.

Distribution and habitat

It is native to the Mediterranean region, and has naturalized in many other locales. It grows satisfactorily in gardens in most of Europe, such as Denmark, France, Germany, the United Kingdom, and Ireland. It is not a perennial, but it remains in the garden from year to year by self-seeding.

Toxicity

In addition to the liver-toxic pyrrolizidine alkaloids found in the leaves and seed oil, the German Federal Institute for Risk Assessment has advised that honey from borage contains

(PAs), transferred to the honey through pollen collected at borage plants, and advise that commercial honey production could select for raw honey with limited PA content to prevent contamination.

Uses

Traditionally, borage was cultivated for culinary and medicinal uses, although today, commercial cultivation is mainly as an oilseed. Borage is used as either a fresh vegetable or a dried herb. As a fresh vegetable, borage, with a

cucumber The cucumber (''Cucumis sativus'') is a widely-cultivated creeping vine plant in the family Cucurbitaceae that bears cylindrical to spherical fruits, which are used as culinary vegetables. The flower has a sweet, honey-like taste and is often used to decorate

dessert Dessert is a course (food), course that concludes a meal; the course consists of sweet foods, such as cake, biscuit, ice cream, and possibly a beverage, such as dessert wine or liqueur. Some cultures sweeten foods that are more commonly umami, ...

s and cocktails, sometimes frozen in ice cubes. Vegetable use of borage is common in Germany, in the Spanish regions of Aragón and

Navarre Navarre ( ; ; ), officially the Chartered Community of Navarre, is a landlocked foral autonomous community and province in northern Spain, bordering the Basque Autonomous Community, La Rioja, and Aragon in Spain and New Aquitaine in France. ...

, on the Greek island of

Crete Crete ( ; , Modern Greek, Modern: , Ancient Greek, Ancient: ) is the largest and most populous of the Greek islands, the List of islands by area, 88th largest island in the world and the List of islands in the Mediterranean#By area, fifth la ...

, and in the northern Italian region of

Liguria Liguria (; ; , ) is a Regions of Italy, region of north-western Italy; its Capital city, capital is Genoa. Its territory is crossed by the Alps and the Apennine Mountains, Apennines Mountain chain, mountain range and is roughly coextensive with ...

. Although often used in soups, one of the better known German borage recipes is the

Frankfurt Frankfurt am Main () is the most populous city in the States of Germany, German state of Hesse. Its 773,068 inhabitants as of 2022 make it the List of cities in Germany by population, fifth-most populous city in Germany. Located in the forela ...

speciality ''grüne Soße'' ("green sauce"). In Liguria, Italy, borage (in Italian, ''borragine'') is commonly used as a filling of the traditional pasta ravioli and pansoti. It is used to flavour pickled

gherkin A pickled cucumber – commonly known as a pickle in the United States, Canada and Australia and a gherkin ( ) in Britain, Ireland, South Africa, and New Zealand – is a usually small or miniature cucumber that has been pickled in a brine, ...

s in

Poland Poland, officially the Republic of Poland, is a country in Central Europe. It extends from the Baltic Sea in the north to the Sudetes and Carpathian Mountains in the south, bordered by Lithuania and Russia to the northeast, Belarus and Ukrai ...

and Russia. The flowers produce copious nectar which is used by honeybees to make a light and delicate honey. Borage-aragonese style600

Beverage

Borage is traditionally used as a garnish in the Pimms Cup

cocktail A cocktail is a mixed drink, usually alcoholic beverage, alcoholic. Most commonly, a cocktail is a combination of one or more liquor, spirits mixed with other ingredients, such as juices, flavored syrups, tonic water, Shrub (drink), shrubs, and ...

, but is nowadays often replaced by a long sliver of cucumber peel or by

mint Mint or The Mint may refer to: Plants * Lamiaceae, the mint family ** ''Mentha'', the genus of plants commonly known as "mint" Coins and collectibles * Mint (facility), a facility for manufacturing coins * Mint condition, a state of like-new ...

. It is also one of the key botanicals in Gilpin's Westmorland Extra Dry Gin. The author of ''Cups and their Customs'' notes that a sprig or two of borage "communicates a peculiar refreshing flavour" to any cool drink. In Persian cuisine, borage tea (using the dried purple flowers) is called گل گاوزبان : ''gol gâvzabân'', "cow's-tongue-flower".

Herbal medicine

Traditionally, ''Borago officinalis'' has been used in hyperactive

gastrointestinal The gastrointestinal tract (GI tract, digestive tract, alimentary canal) is the tract or passageway of the digestive system that leads from the mouth to the anus. The tract is the largest of the body's systems, after the cardiovascular system. ...

respiratory The respiratory system (also respiratory apparatus, ventilatory system) is a biological system consisting of specific organs and structures used for gas exchange in animals and plants. The anatomy and physiology that make this happen varies gr ...

and

cardiovascular In vertebrates, the circulatory system is a system of organs that includes the heart, blood vessels, and blood which is circulated throughout the body. It includes the cardiovascular system, or vascular system, that consists of the heart a ...

disorders, such as gastrointestinal ( colic,

cramps A cramp is a sudden, involuntary, painful skeletal muscle contraction or overshortening associated with electrical activity. While generally temporary and non-damaging, they can cause significant pain and a paralysis-like immobility of the affe ...

diarrhea Diarrhea (American English), also spelled diarrhoea or diarrhœa (British English), is the condition of having at least three loose, liquid, or watery bowel movements in a day. It often lasts for a few days and can result in dehydration d ...

), airways (

asthma Asthma is a common long-term inflammatory disease of the airways of the lungs. It is characterized by variable and recurring symptoms, reversible airflow obstruction, and easily triggered bronchospasms. Symptoms include episodes of wh ...

bronchitis Bronchitis is inflammation of the bronchi (large and medium-sized airways) in the lungs that causes coughing. Bronchitis usually begins as an infection in the nose, ears, throat, or sinuses. The infection then makes its way down to the bronchi. ...

), cardiovascular, ( cardiotonic,

antihypertensive Antihypertensives are a class of drugs that are used to treat hypertension (high blood pressure). Antihypertensive therapy seeks to prevent the complications of high blood pressure, such as stroke, heart failure, kidney failure and myocardial infa ...

and blood purifier),

urinary The human urinary system, also known as the urinary tract or renal system, consists of the kidneys, ureters, bladder, and the urethra. The purpose of the urinary system is to eliminate waste from the body, regulate blood volume and blood pressu ...

(diuretic and kidney/bladder disorders). One case of

status epilepticus Status epilepticus (SE), or status seizure, is a medical condition with abnormally prolonged seizures. It can have long-term consequences, manifesting as a single seizure lasting more than a defined time (time point 1), or 2 or more seizures over ...

has been reported that was associated with borage oil ingestion. A

methanol Methanol (also called methyl alcohol and wood spirit, amongst other names) is an organic chemical compound and the simplest aliphatic Alcohol (chemistry), alcohol, with the chemical formula (a methyl group linked to a hydroxyl group, often ab ...

extract of borage has shown strong amoebicidal activity ''

in vitro ''In vitro'' (meaning ''in glass'', or ''in the glass'') Research, studies are performed with Cell (biology), cells or biological molecules outside their normal biological context. Colloquially called "test-tube experiments", these studies in ...

''. The 50% inhibitory concentration () of the extract against ''

Entamoeba histolytica ''Entamoeba histolytica'' is an anaerobic organism, anaerobic parasitic amoebozoan, part of the genus ''Entamoeba''. Predominantly infecting humans and other primates causing amoebiasis, ''E. histolytica'' is estimated to infect about 35-50 mil ...

'' was 33 μg/mLl.

Companion planting

Borage is used in

companion plant Companion planting in gardening and agriculture is the planting of different crops in proximity for any of a number of different reasons, including weed suppression, pest control, pollination, providing habitat for beneficial insects, maximi ...

ing. It is said to protect or nurse

legumes Legumes are plants in the pea family Fabaceae (or Leguminosae), or the fruit or seeds of such plants. When used as a dry grain for human consumption, the seeds are also called pulses. Legumes are grown agriculturally, primarily for human consu ...

spinach Spinach (''Spinacia oleracea'') is a leafy green flowering plant native to Central Asia, Central and Western Asia. It is of the order Caryophyllales, family Amaranthaceae, subfamily Chenopodioideae. Its leaves are a common vegetable consumed eit ...

, brassicas, and

strawberries The garden strawberry (or simply strawberry; ''Fragaria × ananassa'') is a widely grown hybrid plant cultivated worldwide for its fruit. The genus ''Fragaria'', the strawberries, is in the rose family, Rosaceae. The fruit is appreciated f ...

. It is also said to be a good companion plant to

tomatoes The tomato (, ), ''Solanum lycopersicum'', is a plant whose fruit is an edible berry that is eaten as a vegetable. The tomato is a member of the nightshade family that includes tobacco, potato, and chili peppers. It originated from and was d ...

because it confuses the mother moths of tomato hornworms or manduca looking for a place to lay their eggs. Claims that it improves tomato growth and makes them taste better remain unsubstantiated.

In culture

Pliny the Elder Gaius Plinius Secundus (AD 23/24 79), known in English as Pliny the Elder ( ), was a Roman Empire, Roman author, Natural history, naturalist, and naval and army commander of the early Roman Empire, and a friend of the Roman emperor, emperor Vesp ...

and

Dioscorides Pedanius Dioscorides (, ; 40–90 AD), "the father of pharmacognosy", was a Greek physician, pharmacologist, botanist, and author of (in the original , , both meaning "On Materia medica, Medical Material") , a 5-volume Greek encyclopedic phar ...

said that borage was the nepenthe (νηπενθές : nēpenthés) mentioned in

Homer Homer (; , ; possibly born ) was an Ancient Greece, Ancient Greek poet who is credited as the author of the ''Iliad'' and the ''Odyssey'', two epic poems that are foundational works of ancient Greek literature. Despite doubts about his autho ...

, which caused forgetfulness when mixed with wine. King Henry VIII's last wife,

Catherine Parr Catherine Parr ( – 5 September 1548) was Queen of England and Ireland as the last of the six wives of King Henry VIII from their marriage on 12 July 1543 until Henry's death on 28 January 1547. Catherine was the final queen consort o ...

, used borage in a concoction to treat melancholy.Susan James. Catherine Parr: Henry VIII's Last Love, 2010

Francis Bacon Francis Bacon, 1st Viscount St Alban (; 22 January 1561 – 9 April 1626) was an English philosopher and statesman who served as Attorney General and Lord Chancellor of England under King James I. Bacon argued for the importance of nat ...

thought that borage had "an excellent spirit to repress the fuliginous vapour of dusky melancholie".

John Gerard John Gerard (also John Gerarde, 1545–1612) was an English herbalist with a large garden in Holborn, now part of London. His 1,484-page illustrated ''Herball, or Generall Historie of Plantes'', first published in 1597, became a popular garde ...

's ''Herball'' mentions an old verse concerning the plant: "''Ego Borago, Gaudia semper ago'' (I, Borage, bring always joys)". He asserts:

References

External links

https://persianmama.com/chai-gol-gavzaban-brewed-borage-tea/ https://www.pinterest.ca/pin/557179785128125722/ * * {{Authority control Boraginoideae Herbs Leaf vegetables Medicinal plants of Asia Flora of Europe Edible plants Taxa named by Carl Linnaeus Melliferous flowers