Bonnie Jean Mathieson (May 10, 1945 – January 8, 2018) was an American
biomedical scientist A biomedical scientist is a scientist trained in biology, particularly in the context of medical laboratory sciences or laboratory medicine. These scientists work to gain knowledge on the main principles of how the human body works and to find new w ...
and pioneer in HIV vaccine research. Mathieson worked at the
National Institutes of Health
The National Institutes of Health, commonly referred to as NIH (with each letter pronounced individually), is the primary agency of the United States government
The federal government of the United States (U.S. federal government or U ...
(NIH) for 43 years. She played a fundamental role in NIH HIV/AIDS research, vaccine programs, and scientific policy.
Early life and education
Mathieson was born May 10, 1945. She was the oldest of seven siblings. They were raised on a farm in
Illinois
Illinois ( ) is a state in the Midwestern United States. Its largest metropolitan areas include the Chicago metropolitan area, and the Metro East section, of Greater St. Louis. Other smaller metropolitan areas include, Peoria and Roc ...
.
She completed a Bachelor of Science in botany from
University of Illinois
The University of Illinois Urbana-Champaign (U of I, Illinois, University of Illinois, or UIUC) is a public land-grant research university in Illinois in the twin cities of Champaign and Urbana. It is the flagship institution of the Unive ...
in 1967. She researched retrovirology, immunology, and genetics at
Stanford University where she completed a master's degree in medical microbiology.
In 1975, Mathieson earned a doctor philosophy in biology from the
Memorial Sloan Kettering Cancer Center
Memorial Sloan Kettering Cancer Center (MSK or MSKCC) is a cancer treatment and research institution in the borough of Manhattan in New York City, founded in 1884 as the New York Cancer Hospital. MSKCC is one of 52 National Cancer Institute� ...
and
Weill Cornell Medicine
The Joan & Sanford I. Weill Medical College of Cornell University is Cornell University's biomedical research unit and medical school located in Upper East Side, Manhattan, New York City, New York.
Weill Cornell Medicine is affiliated with New ...
of
Cornell University
Cornell University is a private statutory land-grant research university based in Ithaca, New York. It is a member of the Ivy League. Founded in 1865 by Ezra Cornell and Andrew Dickson White, Cornell was founded with the intention to ...
in
New York City
New York, often called New York City or NYC, is the most populous city in the United States. With a 2020 population of 8,804,190 distributed over , New York City is also the most densely populated major city in the U ...
.
Her dissertation was titled ''Selective expression of surface components on differentiated cells of the mouse: immunoselection of Y-bearing sperm in an in vitro fertilization system and expression of the thymocyte surface markers G(IX), TL and LY in tetraparental mice''. She was a post-doctoral researcher and staff fellow at
National Institute of Allergy and Infectious Diseases
The National Institute of Allergy and Infectious Diseases (NIAID, ) is one of the 27 institutes and centers that make up the National Institutes of Health (NIH), an agency of the United States Department of Health and Human Services (HHS). NIAID's ...
(NIAID) where she researched lymphocyte surface markers and T cell subsets from 1975 to 1982.
Career
Mathieson researched T and B lymphocytes at
Basel Institute for Immunology
The Basel Institute for Immunology (BII) was founded in 1969 as a basic research institute in immunology located at 487 Grenzacherstrasse, Basel, Switzerland on the Rhine River down the street from the main Hoffmann-La Roche campus near the Swiss- ...
as a member from 1982 to 1983. From 1983 to 1989, she studied NK cells and T cell subsets as the head of a laboratory in the Biological Response Modifiers Program at the
NCI-Frederick. Mathieson served as a program officer in the Vaccine Branch in the Division of AIDS in NIAID from 1989 to 1995. As a program officer, she developed
funding opportunity announcements for HIV vaccine, immunology, and pediatric AIDS research. Mathieson is a past chair of the HIV/AIDS Vaccine Coordinating Committee in the Office of AIDS Research (OAR). She was on the WHO-UNAIDS Vaccine Advisory Committee for seven years.
Mathieson also served on review boards for the World Health Organization, European Commission, Canada and the Gates Foundation. She published more than 125 articles and chapters. She served as a health scientist administrator in OAR. She was the lead for HIV/AIDS vaccines at OAR and advanced the NIH AIDS vaccine program through supporting vaccine trials and developing a vaccine scholars program designed to train young scientists.
Mathieson was an advocate for young people, women, and early-career investigators.
Her colleagues knew her as an international leader in the HIV vaccine field and a supporter of research to prevent HIV and improve the health and outcomes of people living with HIV. Mathieson retired from the National Institutes of Health on December 29, 2017. She had a 43 year long career at the NIH.
Awards and honors
Mathieson routinely received performance awards during her tenure at NIH. She won an Alumnus Award from Weill Cornell Medical College.
Personal life
Mathieson was married to Donald and had a daughter and son. She died unexpectedly on January 8, 2018, while snorkeling in
Aruba when she had a massive heart attack.
A memorial service was held at the
Woodend.
Mathieson was survived by her husband, children, grandchildren, and five siblings. She was preceded in death by one sister.
References
{{DEFAULTSORT:Mathieson, Bonnie
1945 births
2018 deaths
20th-century American women scientists
21st-century American women scientists
20th-century American biologists
21st-century American biologists
American women biologists
Scientists from Illinois
National Institutes of Health people
HIV/AIDS researchers
Weill Cornell Medical College alumni
University of Illinois alumni
Stanford University alumni
American medical researchers
Women medical researchers