
Bariatric surgery (also known as metabolic surgery or weight loss surgery) is a surgical procedure used to manage
obesity
Obesity is a medical condition, considered by multiple organizations to be a disease, in which excess Adipose tissue, body fat has accumulated to such an extent that it can potentially have negative effects on health. People are classifi ...
and obesity-related conditions.
Long term weight loss with bariatric surgery may be achieved through alteration of gut hormones, physical reduction of stomach size (stomach reduction surgery),
reduction of nutrient absorption, or a combination of these.
Standard of care
In tort law, the standard of care is the only degree of prudence and caution required of an individual who is under a duty of care.
The requirements of the standard are closely dependent on circumstances. Whether the standard of care has been b ...
procedures include
Roux en-Y bypass,
sleeve gastrectomy, and
biliopancreatic diversion with duodenal switch, from which weight loss is largely achieved by altering gut hormone levels responsible for hunger and satiety, leading to a new hormonal weight
set point.
In morbidly obese people, bariatric surgery is the most effective treatment for weight loss and reducing complications. A 2021
meta-analysis
Meta-analysis is a method of synthesis of quantitative data from multiple independent studies addressing a common research question. An important part of this method involves computing a combined effect size across all of the studies. As such, th ...
found that bariatric surgery was associated with reduction in
all-cause mortality among obese adults with or without
type 2 diabetes
Type 2 diabetes (T2D), formerly known as adult-onset diabetes, is a form of diabetes mellitus that is characterized by high blood sugar, insulin resistance, and relative lack of insulin. Common symptoms include increased thirst, frequent ...
.
This meta-analysis also found that median life-expectancy was 9.3 years longer for obese adults with diabetes who received bariatric surgery as compared to routine (non-surgical) care, whereas the life expectancy gain was 5.1 years longer for obese adults without diabetes.
[ The risk of death in the period following surgery is less than 1 in 1,000. Bariatric surgery may also lower disease risk, including improvement in ]cardiovascular disease
Cardiovascular disease (CVD) is any disease involving the heart or blood vessels. CVDs constitute a class of diseases that includes: coronary artery diseases (e.g. angina, heart attack), heart failure, hypertensive heart disease, rheumati ...
risk factor
In epidemiology, a risk factor or determinant is a variable associated with an increased risk of disease or infection.
Due to a lack of harmonization across disciplines, determinant, in its more widely accepted scientific meaning, is often use ...
s, fatty liver disease, and diabetes management.
Stomach reduction surgery is frequently used for cases where traditional weight loss approaches, consisting of diet and physical activity, have proven insufficient, or when obesity
Obesity is a medical condition, considered by multiple organizations to be a disease, in which excess Adipose tissue, body fat has accumulated to such an extent that it can potentially have negative effects on health. People are classifi ...
already significantly affects well-being and general health. The weight-loss procedure involves reducing food intake. Some individuals might suppress bodily functions to reduce the absorption of carbohydrates
A carbohydrate () is a biomolecule composed of carbon (C), hydrogen (H), and oxygen (O) atoms. The typical hydrogen-to-oxygen atomic ratio is 2:1, analogous to that of water, and is represented by the empirical formula (where ''m'' and ''n'' ma ...
, fats, calories
The calorie is a unit of energy that originated from the caloric theory of heat. The large calorie, food calorie, dietary calorie, kilocalorie, or kilogram calorie is defined as the amount of heat needed to raise the temperature of one liter o ...
, and proteins
Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residues. Proteins perform a vast array of functions within organisms, including catalysing metabolic reactions, DNA replication, re ...
. The outcome is a significant reduction in BMI. The efficacy of stomach reduction surgery varies depending on the specific type of procedure. There are two primary divisions of surgery, specifically gastric sleeve surgery and gastric bypass
Gastric bypass surgery refers to a technique in which the stomach is divided into a small upper pouch and a much larger lower "remnant" pouch, where the small intestine is rearranged to connect to both. Surgeons have developed several differen ...
surgery.
the American Society of Metabolic and Bariatric Surgery and International Federation for the Surgery of Obesity recommended consideration of bariatric surgery for adults meeting two specific criteria: people with a body mass index
Body mass index (BMI) is a value derived from the mass (Mass versus weight, weight) and height of a person. The BMI is defined as the human body weight, body mass divided by the square (algebra), square of the human height, body height, and is ...
(BMI) of more than 35 whether or not they have an obesity-associated condition, and people with a BMI of 30–35 who have metabolic syndrome
Metabolic syndrome is a clustering of at least three of the following five medical conditions: abdominal obesity, high blood pressure, high blood sugar, high serum triglycerides, and low serum high-density lipoprotein (HDL).
Metabolic syndro ...
. However, these designated BMI ranges do not hold the same meaning in particular populations, such as among Asian individuals, for whom bariatric surgery may be considered when a BMI is more than 27.5. Similarly, the American Academy of Pediatrics
The American Academy of Pediatrics (AAP) is the largest professional association of pediatricians in the United States. It is headquartered in Itasca, Illinois, and maintains an office in Washington, D.C. The AAP has published hundreds of poli ...
recommends bariatric surgery for adolescents 13 and older with a BMI greater than 120% of the 95th percentile for age and sex.
Medical uses
Bariatric surgery has proven to be the most effective obesity treatment option for enduring weight loss. Along with this weight reduction, the procedure reduces risk of cardiovascular diseases, type 2 diabetes, fatty liver disease, depression syndromes, among others. While often effective, numerous barriers to shared decision making between the medical provider and person affected include lack of insurance coverage or understanding how it functions, a lack of knowledge about procedures, conflicts with organizational priorities and care coordination, and tools supporting people who need the surgery.
Eligibility and guidelines
Historically, eligibility for bariatric surgery was defined as a BMI greater than 40, or a BMI more than 35 with an obesity-associated comorbidity, as based on the 1991 NIH Consensus Statement. In the three decades that followed, obesity rates continued to rise, laparoscopic
Laparoscopy () is an operation performed in the abdomen or human pelvis, pelvis using small Surgical incision, incisions (usually 0.5–1.5 cm) with the aid of a camera. The laparoscope aids diagnosis or therapeutic interventions with a few ...
surgical techniques made the procedure safer, and high-quality research showed effectiveness at improving health among various conditions. In October 2022, ASMBS/IFSO revised the eligibility criteria, which include all adult patients with a BMI greater than 35, and those with a BMI more than 30 with metabolic syndrome
Metabolic syndrome is a clustering of at least three of the following five medical conditions: abdominal obesity, high blood pressure, high blood sugar, high serum triglycerides, and low serum high-density lipoprotein (HDL).
Metabolic syndro ...
. However, BMI is a limited measurement, for which factors such as ethnicity are not used in the BMI calculation. Eligibility criteria for bariatric surgery are modified for people who identify as a part of the Asian population with a BMI of more than 27.5.
Stomach reduction surgeries were highly recommended for patients who meet these criteria: BMI>40 (type 3 obesity), BMI>35 (type 2 obesity), with specific comorbid
In medicine, comorbidity refers to the simultaneous presence of two or more medical conditions in a patient; often co-occurring (that is, concomitant or concurrent) with a primary condition. It originates from the Latin term (meaning "sicknes ...
conditions such as type 2 diabetes
Type 2 diabetes (T2D), formerly known as adult-onset diabetes, is a form of diabetes mellitus that is characterized by high blood sugar, insulin resistance, and relative lack of insulin. Common symptoms include increased thirst, frequent ...
, hypertension
Hypertension, also known as high blood pressure, is a Chronic condition, long-term Disease, medical condition in which the blood pressure in the artery, arteries is persistently elevated. High blood pressure usually does not cause symptoms i ...
, dyslipidemia
Dyslipidemia is a metabolic disorder characterized by abnormally high or low amounts of any or all lipids (e.g. fats, triglycerides, cholesterol, phospholipids) or lipoproteins in the blood. Dyslipidemia is a risk factor for the development of ...
, etc.
the American Academy of Pediatrics
The American Academy of Pediatrics (AAP) is the largest professional association of pediatricians in the United States. It is headquartered in Itasca, Illinois, and maintains an office in Washington, D.C. The AAP has published hundreds of poli ...
recommended bariatric surgery without age-based eligibility limits under the following indications: BMI more than 35 with severe comorbidity, such as obstructive sleep apnea
Obstructive sleep apnea (OSA) is the most common sleep-related breathing disorder and is characterized by recurrent episodes of complete or partial airway obstruction, obstruction of the respiratory tract#Upper respiratory tract, upper airway lea ...
(Apnea-Hypopnea Index above 0.5), type 2 diabetes, idiopathic intracranial hypertension
Idiopathic intracranial hypertension (IIH), previously known as pseudotumor cerebri and benign intracranial hypertension, is a condition characterized by increased intracranial pressure (pressure around the brain) without a detectable cause. The m ...
, nonalcoholic steatohepatitis, Blount disease, slipped capital femoral epiphysis
Slipped capital femoral epiphysis (SCFE or skiffy, slipped upper femoral epiphysis, SUFE or , coxa vara adolescentium) is a medical term referring to a fracture through the growth plate (physis), which results in slippage of the overlying end of ...
, gastroesophageal reflux disease
Gastroesophageal reflux disease (GERD) or gastro-oesophageal reflux disease (GORD) is a chronic upper gastrointestinal disease in which stomach content persistently and regularly flows up into the esophagus, resulting in symptoms and/or ...
, and idiopathic hypertension or a BMI above 40 without comorbidities. Surgery is contraindicated with a medically correctable cause of obesity, substance abuse, concurrent or planned pregnancy, eating disorder
An eating disorder is a mental disorder defined by abnormal eating behaviors that adversely affect a person's health, physical or mental health, mental health. These behaviors may include eating too much food or too little food. Types of eatin ...
, or inability to adhere to postoperative recommendations and mandatory lifestyle changes.
When counseling a patient on bariatric procedures, providers take an interdisciplinary approach. Psychiatric screening is also critical for determining postoperative success. People with a BMI of 40 or greater have a 5-fold risk of depression, and half of bariatric surgery candidates are depressed. Among bariatric surgery candidates and those who undergo bariatric surgery, mental health-related conditions including anxiety disorder
Anxiety disorders are a group of mental disorders characterized by significant and uncontrollable feelings of anxiety and fear such that a person's social, occupational, and personal functions are significantly impaired. Anxiety may cause phys ...
s, eating disorder
An eating disorder is a mental disorder defined by abnormal eating behaviors that adversely affect a person's health, physical or mental health, mental health. These behaviors may include eating too much food or too little food. Types of eatin ...
s, and substance use are also more commonly reported.
Age
Elderly patients will face higher postoperative complications due to frailty of elderly patients. The adolescents
Adolescence () is a transitional stage of human physical and psychological development that generally occurs during the period from puberty to adulthood (typically corresponding to the age of majority). Adolescence is usually associated with ...
who performed stomach reduction surgery showed better results and there is no negative impact on linear/puberty
Puberty is the process of physical changes through which a child's body matures into an adult body capable of sexual reproduction. It is initiated by hormonal signals from the brain to the gonads: the ovaries in a female, the testicles i ...
growth.
Contraindications
Stomach reduction surgery is not suitable for people with the following conditions:
*History of severe gastrointestinal disease:
** Crohn's disease
Crohn's disease is a type of inflammatory bowel disease (IBD) that may affect any segment of the gastrointestinal tract. Symptoms often include abdominal pain, diarrhea, fever, abdominal distension, and weight loss. Complications outside of the ...
–RYGB surgery limited.
** Active peptic ulcers disease.
** Esophagitis
Esophagitis, also spelled oesophagitis, is a disease characterized by inflammation of the esophagus. The esophagus is a tube composed of a mucosal lining, and longitudinal and circular smooth muscle fibers. It connects the pharynx to the stoma ...
in severe stage.
*Severe cardiovascular disease
** Heart failure
Heart failure (HF), also known as congestive heart failure (CHF), is a syndrome caused by an impairment in the heart's ability to Cardiac cycle, fill with and pump blood.
Although symptoms vary based on which side of the heart is affected, HF ...
** Coronary artery disease
Coronary artery disease (CAD), also called coronary heart disease (CHD), or ischemic heart disease (IHD), is a type of cardiovascular disease, heart disease involving Ischemia, the reduction of blood flow to the cardiac muscle due to a build-up ...
** Portal hypertension
Portal hypertension is defined as increased portal venous pressure, with a hepatic venous pressure gradient greater than 5 mmHg. Normal portal pressure is 1–4 mmHg; clinically insignificant portal hypertension is present at portal pressures 5� ...
*Cancer: active cancer
Cancer is a group of diseases involving Cell growth#Disorders, abnormal cell growth with the potential to Invasion (cancer), invade or Metastasis, spread to other parts of the body. These contrast with benign tumors, which do not spread. Po ...
diagnosis
*Pregnancy: pregnant (within 12-18 month)
*Psychiatric: lower level of mental capacity or untreated mental disorders
*Blood clotting: Coagulopathy
Coagulopathy (also called a bleeding disorder) is a condition in which the blood's ability to coagulate (form clots) is impaired. This condition can cause a tendency toward prolonged or excessive bleeding ( bleeding diathesis), which may occur s ...
issue
Weight loss
In adults, malabsorptive procedures lead to more weight loss than restrictive procedures, but they have a higher risk profile. Gastric banding is the least invasive, so it may offer fewer complications, while gastric bypass may offer the highest initial and most sustainable weight loss. A single protocol is not superior to the other. In one 2019 systematic review, estimated weight loss (EWL) for each surgical protocol is as follows: 56.7% for gastric bypass, 45.9% for gastric banding, 74.1% for biliopancreatic bypass +/- duodenal switch and 58.3% for sleeve gastrectomy. Most patients do remain obese (BMI 25-35) following surgery despite significant weight loss, and patients with BMI over 40 tended to lose more weight than those with BMI under 40.
Concerning metabolic syndrome
Metabolic syndrome is a clustering of at least three of the following five medical conditions: abdominal obesity, high blood pressure, high blood sugar, high serum triglycerides, and low serum high-density lipoprotein (HDL).
Metabolic syndro ...
, bariatric surgery patients were able to achieve remission 2.4 times as often as those who underwent nonsurgical treatment. No significant difference was noted for changes in cholesterol, or LDL, but HDL did increase in the surgical groups, and reduction in blood pressure was variable between studies.
Type 2 diabetes mellitus
Studies of bariatric surgery for type 2 diabetes ( T2DM) within the obese population show that 58% prioritize the improvement of diabetes, while 33% pursued surgery for weight loss alone. While weight loss is essential in T2DM management, sustaining improvements long-term is challenging; 50% to 90% of people struggle to achieve adequate diabetes control, suggesting the need for alternative interventions. In this context, studies have reported an 85–90% resolution of T2DM after bariatric surgery, measured by reductions in fasting plasma glucose and HbA1C
Glycated hemoglobin, also called glycohemoglobin, is a form of hemoglobin (Hb) that is chemically linked to a sugar. Most monosaccharides, including glucose, galactose, and fructose, spontaneously (that is, non-enzymatically) bond with hemoglob ...
levels, and remission rates of up to 74% two years post-surgery. Bariatric surgery is considered for individuals with new-onset T2DM and obesity, although the level of improvement may be slightly less.
The relative risk reductions associated with bariatric surgery are 61%, 64%, and 77% for the development of T2DM, hypertension, and dyslipidemia, respectively, highlighting the efficacy of bariatric surgery in prevention as well as resolution of chronic obesity. Predictors for post-operative diabetes resolution include the current method of diabetes control, adequate blood sugar control, age, duration of diabetes, and waist circumference.
Bariatric surgery likewise plays a role in the reduction of medication use. During postoperative follow-up, 76% of people discontinued the use of insulin, while 62% no longer required T2DM medications at all.
Reduced mortality and morbidity
A 2021 meta-analysis found that bariatric surgery was associated with 59% and 30% reductions in all-cause mortality among obese adults with or without type 2 diabetes
Type 2 diabetes (T2D), formerly known as adult-onset diabetes, is a form of diabetes mellitus that is characterized by high blood sugar, insulin resistance, and relative lack of insulin. Common symptoms include increased thirst, frequent ...
respectively. It also found that median life expectancy was 9 years longer for obese adults with diabetes who received bariatric surgery as compared to routine (non-surgical) care, whereas the life expectancy gain was 5 years longer for obese adults without diabetes. The overall cancer risk in bariatric surgery patients was decreased by 44%, especially in colorectal, endometrial, breast, and ovarian cancer. Improvements in cardiovascular health are the most well-described changes after bariatric surgery, with notable reductions in the incidence of stroke (except in patients with T2DM), heart attack, atrial fibrillation, all-cause cardiovascular mortality, and ischemic heart disease.
Bariatric surgery in older patients is a safety concern; the relative benefits and risks in this population are not known.
Fertility and pregnancy
In 2017, the American Society for Metabolic and Bariatric Surgery stated that it was not clear whether medical weight-loss treatments or bariatric surgery affected subsequent treatments for infertility in both men and women.
Bariatric surgery reduces the risk of gestational diabetes
Gestational diabetes is a condition in which a woman without diabetes develops hyperglycemia, high blood sugar levels during pregnancy. Gestational diabetes generally results in few symptoms. Obesity increases the rate of pre-eclampsia, cesarea ...
and hypertensive disorders of pregnancy
Hypertensive disease of pregnancy, also known as maternal hypertensive disorder, is a group of high blood pressure disorders that include preeclampsia, preeclampsia superimposed on chronic hypertension, gestational hypertension, and chronic hyper ...
in women who later become pregnant, but increases the risks of preterm birth
Preterm birth, also known as premature birth, is the Childbirth, birth of a baby at fewer than 37 weeks Gestational age (obstetrics), gestational age, as opposed to full-term delivery at approximately 40 weeks. Extreme preterm is less than 28 ...
and maternal anemia
Anemia (also spelt anaemia in British English) is a blood disorder in which the blood has a reduced ability to carry oxygen. This can be due to a lower than normal number of red blood cells, a reduction in the amount of hemoglobin availabl ...
. A 2021 systematic review found that post-bariatric surgery normalized hormonal levels and menstrual cycles, and improved fertility, with no increased short-term risk of miscarriages or congenital malformations.
For women with polycystic ovary syndrome
Polycystic ovary syndrome, or polycystic ovarian syndrome, (PCOS) is the most common endocrine disorder in women of reproductive age. The name is a misnomer, as not all women with this condition develop cysts on their ovaries. The name origin ...
, post-operatively there tends to be a reduction in menstrual irregularity, hirsutism
Hirsutism is excessive body hair on parts of the body where hair is normally absent or minimal. The word is from early 17th century: from Latin ''hirsutus'' meaning "hairy". It usually refers to a male pattern of hair growth in a female that ma ...
, infertility, and the overall prevalence of polycystic ovary syndrome is reduced by bariatric surgery at 12 and 23 months.
Mental health
Among people seeking bariatric surgery, pre-operative mental health disorders are commonly reported. Some studies indicate that psychological health can improve after bariatric surgery, due in part to improved body image, self-esteem, and change in self-concept; these findings were found in children (see Considerations in adolescent patients below). Bariatric surgery has consistently been associated with postoperative decreases in depression symptoms and reduced severity.
Risks and complications
Weight loss surgery in adults is associated with an elevated risk of complications compared to nonsurgical treatments for obesity. Complications can be separated into 2 stages, early complication (within 30 days after surgeries) and late complications (after 30 days).
The overall risk of mortality is low in bariatric surgery at 0 to .01%. Severe complications, such as gastric perforation or necrosis, have been significantly reduced by improved surgical experience and training. Bariatric surgery morbidity is also low at 5%. In fact, several studies have reported a reduced overall long-term all-cause mortality compared to controls. However, obese populations maintain an elevated risk of disease and mortality compared to the general population even after surgery, therefore elevated mortality after surgery may be related to the ongoing complications of existing obesity-related disease.
The percentage of procedures requiring reoperations due to complications was 8% for adjustable gastric banding, 6% after Roux-en-Y gastric bypass, 1% for sleeve gastrectomy, and 5% after biliopancreatic diversion. Over a 10-year study while using a common data model to allow for comparisons, 9% of patients who received a sleeve gastrectomy required some form of reoperation within 5 years compared to 12% of patients who received a Roux-en-Y gastric bypass. Both of the effects were fewer than those reported with adjustable gastric banding.
Postoperative
Laparoscopic
Laparoscopy () is an operation performed in the abdomen or human pelvis, pelvis using small Surgical incision, incisions (usually 0.5–1.5 cm) with the aid of a camera. The laparoscope aids diagnosis or therapeutic interventions with a few ...
bariatric surgery requires an average hospital stay of 2–5 days, barring potential complications. Minimally invasive procedures (i.e. adjustable gastric band) tend to have less complications than open procedures (i.e. Roux-en-Y). Similar to other surgical procedures, there is a risk of atelectasis (collapse of small airways) and pleural effusion (fluid buildup in lungs), and pneumonia which tends to be less associated with minimally invasive procedures.
Complications specific to the laparoscopic gastric band procedure include esophageal perforation from the advancement of the calibration probe, gastric perforation from the creation of a retrograde gastric tunnel, esophageal dilation, and acute dilation of the gastric pouch due to malpositioning of the gastric band. Gastric band malpositioning can be devastating, leading to gastric prolapse, overdistention, and resultingly, gastric ischemia and necrosis. Erosion and migration of the band may also occur post-operatively, in which case, if over 50% of the circumference of the band migrates, then surgical repositioning is necessary.
Risks of Roux-en-Y gastric bypass include anastomotic stenosis (narrowing of the intestine where the two segments are rejoined), bleeding, leaks, fistula
In anatomy, a fistula (: fistulas or fistulae ; from Latin ''fistula'', "tube, pipe") is an abnormal connection (i.e. tube) joining two hollow spaces (technically, two epithelialized surfaces), such as blood vessels, intestines, or other h ...
formation, ulcers (ulcers near the rejoined segment), internal hernia, small bowel obstruction, kidney stones, and gallstones. Bowel obstruction tends to be more difficult to diagnose in post-bariatric surgery patients due to their reduced ability to vomit; symptoms mainly involve abdominal pain and are intermittent due to twisting and untwisting of the intestinal mesentery
In human anatomy, the mesentery is an Organ (anatomy), organ that attaches the intestines to the posterior abdominal wall, consisting of a double fold of the peritoneum. It helps (among other functions) in storing Adipose tissue, fat and allowi ...
.
Sleeve gastrectomy also carries a small risk of stenosis, staple line leak, stricture formation, leaks, fistula formation, bleeding, and gastro-esophageal reflux disease (also known as GERD or heartburn).
Deficiencies of micronutrient
Micronutrients are essential chemicals required by organisms in small quantities to perform various biogeochemical processes and regulate physiological functions of cells and organs. By enabling these processes, micronutrients support the heal ...
s like iron (15%), vitamin D, vitamin B12, fat-soluble vitamins, thiamine, and folate are common after bariatric procedures. Such deficiencies are potentiated by alterations in absorption and lack of appetite and often require supplementation. Notably, chronic vitamin D deficiency may contribute to osteoporosis
Osteoporosis is a systemic skeletal disorder characterized by low bone mass, micro-architectural deterioration of bone tissue leading to more porous bone, and consequent increase in Bone fracture, fracture risk.
It is the most common reason f ...
; insufficiency fractures, especially of the upper extremity, are of higher incidence in bariatric surgery patients. Sleeve gastrectomy leads to fewer long-term vitamin deficiencies compared to gastric banding.
Sleeve Gastrectomy (SG)
Early complication: Bleeding
Bleeding, hemorrhage, haemorrhage or blood loss, is blood escaping from the circulatory system from damaged blood vessels. Bleeding can occur internally, or externally either through a natural opening such as the mouth, nose, ear, urethr ...
is present in approximately 5% of cases of sleeve gastrectomy. Symptoms can vary widely, ranging from gastrointestinal bleeding to internal
Internal may refer to:
*Internality as a concept in behavioural economics
*Neijia, internal styles of Chinese martial arts
*Neigong or "internal skills", a type of exercise in meditation associated with Daoism
* ''Internal'' (album) by Safia, 2016 ...
bleeding. Venous thromboembolism
Venous thrombosis is the blockage of a vein caused by a thrombus (blood clot). A common form of venous thrombosis is deep vein thrombosis (DVT), when a blood clot forms in the deep veins. If a thrombus breaks off ( embolizes) and flows to the lun ...
(VTE) may occur, causing a decrease in flow through the splenic system, potentially leading to system collapse or death.
Late complications: They include gastric stenosis
Stenosis () is the abnormal narrowing of a blood vessel or other tubular organ or structure such as foramina and canals. It is also sometimes called a stricture (as in urethral stricture).
''Stricture'' as a term is usually used when narrowing ...
, nutrient deficiencies, and Gastroesophageal reflux disease. For gastric stenosis, the symptoms are food intolerance and vomiting. For th
gastroesophageal reflux disease
which due to post-surgery changes of reduced lower esophageal sphincter
A sphincter is a circular muscle that normally maintains constriction of a natural body passage or orifice and relaxes as required by normal physiological functioning. Sphincters are found in many animals. There are over 60 types in the human bo ...
tension and increased intragastric pressure. Patients may suffer from heartburn
Heartburn is a burning sensation felt behind the breastbone. It is a symptom that is commonly linked to acid reflux and is often triggered by food, particularly fatty, sugary, spicy, chocolate, citrus, onion-based and tomato-based products. Ly ...
after eating or upper abdominal pain
Abdominal pain, also known as a stomach ache, is a symptom associated with both non-serious and serious medical issues. Since the abdomen contains most of the body's vital organs, it can be an indicator of a wide variety of diseases. Given th ...
.
= Roux-En-Y Gastric Bypass (RYGB)
=
An early complication of Roux-En-Y Gastric Bypass: Small bowel obstruction, which can be caused by the internal hernias
A hernia (: hernias or herniae, from Latin, meaning 'rupture') is the abnormal exit of tissue or an organ, such as the bowel, through the wall of the cavity in which it normally resides. The term is also used for the normal development of the i ...
due to the laparoscopic RYGB surgery techniques that were used. And it is life-threatening to patients since it is hard to diagnose through clinical or radiographic
Radiography is an imaging technique using X-rays, gamma rays, or similar ionizing radiation and non-ionizing radiation to view the internal form of an object. Applications of radiography include medical ("diagnostic" radiography and "therapeu ...
imaging. The symptoms included vomiting, abdominal pain and peritonitis
Peritonitis is inflammation of the localized or generalized peritoneum, the lining of the inner wall of the abdomen and covering of the abdominal organs. Symptoms may include severe pain, swelling of the abdomen, fever, or weight loss. One pa ...
. Common complications such as internal gastrointestinal hemorrhage (bleeding) and staple line leakage occur in both surgeries.
Late complication: For the anastomotic stricture, there is a 2.9%-23% chance for patients to experience gastrojejunal anastomosis
An anastomosis (, : anastomoses) is a connection or opening between two things (especially cavities or passages) that are normally diverging or branching, such as between blood vessels, leaf veins, or streams. Such a connection may be normal (su ...
. This complication more often occurs in the laparoscopic
Laparoscopy () is an operation performed in the abdomen or human pelvis, pelvis using small Surgical incision, incisions (usually 0.5–1.5 cm) with the aid of a camera. The laparoscope aids diagnosis or therapeutic interventions with a few ...
era than open RYGB surgery. Symptoms such as difficulty swallowing
Swallowing, also called deglutition or inglutition in scientific and medical contexts, is a physical process of an animal's digestive tract (e.g. that of a human body) that allows for an ingested substance (typically food) to pass from the mou ...
and vomiting
Vomiting (also known as emesis, puking and throwing up) is the forceful expulsion of the contents of one's stomach through the mouth and sometimes the nose.
Vomiting can be the result of ailments like food poisoning, gastroenteritis, pre ...
.
Gastrointestinal
The most common complication, especially after sleeve gastrectomy, is GERD, which may occur in up to 25% of cases. Dumping syndrome (rapid emptying of undigested stomach contents) is another common complication of bariatric surgery, especially after Roux-en-Y, which is further classified into early and late dumping syndrome. Dumping syndrome in some cases may be associated with more efficient weight loss, however, it can be uncomfortable. Symptoms of dumping syndrome include nausea, diarrhea, painful abdominal cramps, bloating, and autonomic symptoms such as tachycardia, palpitations, flushing, and sweating. Early dumping syndrome (emptying within 1 hour of eating) is also associated with a rapid drop in blood pressure, which may cause fainting. Late dumping syndrome is characterized by low blood sugar 1–3 hours after a meal, presenting with palpitations, tremors, sweating, a feeling of faintness, and irritability. Dumping syndrome is best mitigated by consuming small meals and avoiding high carb or high-fat foods.
Gallstones
Rapid weight loss after obesity surgery can contribute to the development of gallstone
A gallstone is a stone formed within the gallbladder from precipitated bile components. The term cholelithiasis may refer to the presence of gallstones or to any disease caused by gallstones, and choledocholithiasis refers to the presence of ...
s, especially at 6 and 18 months. Estimates for prevalence of symptomatic gallstones after Roux-En-Y gastric bypass range from 3–13%.[ The risk of gallstones following bariatric surgery has shown to be higher among those of the female sex.
]
Kidney stones
Kidney stones
Kidney stone disease (known as nephrolithiasis, renal calculus disease, or urolithiasis) is a crystallopathy and occurs when there are too many minerals in the urine and not enough liquid or hydration. This imbalance causes tiny pieces of cr ...
are common after Roux-En-Y gastric bypass, with estimates of prevalence ranging from 7-11%.[ All surgical modalities are associated with a significant increase in the risk of kidney stones compared to nonsurgical weight loss treatment, with biliopancreatic diversion being the most associated at a ten-fold increase in one study.
]
Micronutrient malnutrition
Bariatric surgery as a treatment for obesity can lead to vitamin deficiencies. Long-term follow-up reported deficiencies for vitamins D, E, A, K and B12. There are guidelines for multivitamin supplementation, but adherence rates are reported to be less than 20%.
Pregnancy
Pregnancy in patients post-bariatric surgery must be carefully monitored. Infant mortality, preterm birth, small fetal size, congenital anomalies, and NICU admission are all elevated in bariatric surgery patients. This elevation in adverse outcomes is thought to be because of malnutrition. Most notably, a reduction in serum folate and iron are well-established correlates to neural tube defects and preterm birth, respectively. People considering pregnancy should consult with their physician before conceiving to optimize their health and nutritional status before pregnancy.
Technique
Mechanisms of action
Bariatric procedures function by a variety of mechanisms, such as alteration of gut hormones, reduction of the gut size (reducing the amount of food that may pass through), and reduction or blockage of nutrient absorption. The distinction in these mechanisms, and which are at work for a particular bariatric procedure is not always clearly defined, as multiple mechanisms may be used by a single procedure. For instance, while sleeve gastrectomy (discussed below) was initially thought to work simply by reducing the size of the stomach, research has begun to elucidate changes in gut hormone signaling as well. The two most frequently performed procedures are sleeve gastrectomy and Roux-en-Y gastric bypass (also called gastric bypass), with sleeve gastrectomy accounting for more than half of all procedures since 2014.
Hormone regulation
Studies have shown that bariatric procedures may have additional effects on the hormones that affect hunger and satiety (such as ghrelin
Ghrelin (; or lenomorelin, INN) is a hormone primarily produced by enteroendocrine cells of the gastrointestinal tract, especially the stomach, and is often called a "hunger hormone" because it increases the drive to eat. Blood levels of ghrel ...
and leptin
Leptin (from Ancient Greek, Greek λεπτός ''leptos'', "thin" or "light" or "small"), also known as obese protein, is a protein hormone predominantly made by adipocytes (cells of adipose tissue). Its primary role is likely to regulate long ...
), despite initial development to target reduction of food intake and/or nutrient absorption. This is especially important when considering the durability of weight loss compared to lifestyle changes. While diet and exercise are essential for maintaining a healthy weight and physical fitness, metabolism typically slows as the individual loses weight, a process known as metabolic adaptation. Thus, efforts for obese individuals to lose weight often stall, or result in weight re-gain. Bariatric surgery is thought to affect the weight "set point," leading to a more durable weight loss. This is not completely understood but may involve the cell-signaling pathways and hunger/satiety hormones.
Restricting food intake
Procedures may reduce food intake by reducing the size of the stomach that is available to hold a meal (see below: gastric sleeve or stomach folding). Filling the stomach faster enables an individual to feel more full after a smaller meal.
Nutrient absorption
Procedures may reduce the amount of intestine that food passes through to decrease the absorption of nutrients from food. For example, a Roux-en-Y gastric bypass connects the stomach to a more distal part of the intestine, which reduces the ability of the intestines to absorb nutrients from the food.
Disruption of the gut-brain axis by partial vagotomy
Roux-en-Y gastric bypass disrupts the gastric branches of the vagal nerve completely and sleeve gastrectomy does so partially. Before current bariatriac was introduced, isolated vagotomy was used for the treatment of obesity. Vagotomy leads to a reduction of gastric acid and consequently to a reduction in nutrient absorption and a delay in gastric emptying. In addition, the effect of the hunger hormone Ghrelin is reduced, because it acts through the vagal nerve. This leads to a reduction of the hunger feeling and weight loss.
Most common techniques
Sleeve gastrectomy
Sleeve gastrectomy, also known as a gastric sleeve, is a surgical weight-loss procedure where the stomach
The stomach is a muscular, hollow organ in the upper gastrointestinal tract of Human, humans and many other animals, including several invertebrates. The Ancient Greek name for the stomach is ''gaster'' which is used as ''gastric'' in medical t ...
size is reduced by the surgical removal of a large portion of the stomach, following along the major curve of the stomach. The open edges are then attached (typically with surgical staple
Surgical staples are specialized Staple (fastener), staples used in surgery in place of surgical suture, sutures to close skin wounds or to resection (surgery), resect and/or anastomosis, connect parts of an Organ (biology), organ (e.g. bowels, ...
s, sutures, or both) to leave the stomach shaped more like a tube, or a sleeve, with a banana shape.
The procedure is performed laparoscopic
Laparoscopy () is an operation performed in the abdomen or human pelvis, pelvis using small Surgical incision, incisions (usually 0.5–1.5 cm) with the aid of a camera. The laparoscope aids diagnosis or therapeutic interventions with a few ...
ally and is not reversible. It has been found to produce a weight loss comparable to that of Roux-en-Y gastric bypass. The risk of ulcers or narrowing of the gut due to intestinal strictures is less so with sleeve gastrectomy versus Roux-en-Y gastric bypass, but it is not as effective at treating GERD
Gastroesophageal reflux disease (GERD) or gastro-oesophageal reflux disease (GORD) is a chronic upper gastrointestinal disease in which stomach content persistently and regularly flows up into the esophagus, resulting in symptoms and/or ...
or type 2 diabetes.
This was the most commonly performed bariatric surgery in the United States, and is one of the two most commonly performed bariatric surgeries in the world. Though initially thought to work strictly by reducing the size of the stomach, recent research has shown that there are also changes in gut signaling hormones with this procedure leading to weight loss.
The sleeve gastrectomy mechanism works by creating a narrow gastric lumen which restricts food intake and prevents receptive relaxation, alongside ongoing research into hormonal
A hormone (from the Greek participle , "setting in motion") is a class of signaling molecules in multicellular organisms that are sent to distant organs or tissues by complex biological processes to regulate physiology and behavior. Hormones a ...
changes, and gastrointestinal
The gastrointestinal tract (GI tract, digestive tract, alimentary canal) is the tract or passageway of the digestive system that leads from the mouth to the anus. The tract is the largest of the body's systems, after the cardiovascular system. ...
motility
Motility is the ability of an organism to move independently using metabolism, metabolic energy. This biological concept encompasses movement at various levels, from whole organisms to cells and subcellular components.
Motility is observed in ...
.
The physical mechanism that will make the SG stand out to other bariatric surgery is its reduction of the storage of the stomach significantly, allowing patients to control their calorie intakes.
The mechanism related to hormone regulation, SG can help to improve Insulin
Insulin (, from Latin ''insula'', 'island') is a peptide hormone produced by beta cells of the pancreatic islets encoded in humans by the insulin (''INS)'' gene. It is the main Anabolism, anabolic hormone of the body. It regulates the metabol ...
sensitivity, aiming for better glucose
Glucose is a sugar with the Chemical formula#Molecular formula, molecular formula , which is often abbreviated as Glc. It is overall the most abundant monosaccharide, a subcategory of carbohydrates. It is mainly made by plants and most algae d ...
regulation and contributing to the remission of type 2 diabetes
Type 2 diabetes (T2D), formerly known as adult-onset diabetes, is a form of diabetes mellitus that is characterized by high blood sugar, insulin resistance, and relative lack of insulin. Common symptoms include increased thirst, frequent ...
in many patients. The levels of gut hormones such as GLP-1
Glucagon-like peptide-1 (GLP-1) is a 30- or 31-amino-acid-long peptide hormone deriving from tissue-specific posttranslational processing of the proglucagon peptide. It is produced and secreted by intestinal enteroendocrine L-cells and certai ...
and PYY increase after operation of SG. GLP-1 enhances insulin
Insulin (, from Latin ''insula'', 'island') is a peptide hormone produced by beta cells of the pancreatic islets encoded in humans by the insulin (''INS)'' gene. It is the main Anabolism, anabolic hormone of the body. It regulates the metabol ...
secretion and has a satiety-inducing effect, while PYY helps reduce appetite
Appetite is the desire to eat food items, usually due to hunger. Appealing foods can stimulate appetite even when hunger is absent, although appetite can be greatly reduced by satiety. Appetite exists in all higher life-forms, and serves to reg ...
. These hormonal changes are pivotal in the metabolic
Metabolism (, from ''metabolē'', "change") is the set of life-sustaining chemical reactions in organisms. The three main functions of metabolism are: the conversion of the energy in food to energy available to run cellular processes; the ...
improvements observed after SG, including better control of blood sugar levels and reduced hunger.
SG will affect the metabolism
Metabolism (, from ''metabolē'', "change") is the set of life-sustaining chemical reactions in organisms. The three main functions of metabolism are: the conversion of the energy in food to energy available to run cellular processes; the co ...
and absorption of nutrients
A nutrient is a substance used by an organism to survive, grow and reproduce. The requirement for dietary nutrient intake applies to animals, plants, fungi and protists. Nutrients can be incorporated into cells for metabolic purposes or excret ...
, hence causing an effect on nutrient dynamics. Postoperative observation shows patients' nutrient levels of Vitamin B1 and B12 have significantly declined, necessitating careful postoperative nutritional management to prevent deficiencies.
Research suggests SG surgery can alter the composition of the gut microbiota
Gut microbiota, gut microbiome, or gut flora are the microorganisms, including bacteria, archaea, fungi, and viruses, that live in the digestive tracts of animals. The gastrointestinal metagenome is the aggregate of all the genomes of the g ...
, which plays a role in obesity and metabolic health. Changes in the gut microbial community post-SG may influence energy
Energy () is the physical quantity, quantitative physical property, property that is transferred to a physical body, body or to a physical system, recognizable in the performance of Work (thermodynamics), work and in the form of heat and l ...
harvest from the diet, impact inflammatory pathways, and affect the host
A host is a person responsible for guests at an event or for providing hospitality during it.
Host may also refer to:
Places
* Host, Pennsylvania, a village in Berks County
* Host Island, in the Wilhelm Archipelago, Antarctica
People
* ...
's metabolic profile.
The key mechanism is gastrointestinal
The gastrointestinal tract (GI tract, digestive tract, alimentary canal) is the tract or passageway of the digestive system that leads from the mouth to the anus. The tract is the largest of the body's systems, after the cardiovascular system. ...
motility
Motility is the ability of an organism to move independently using metabolism, metabolic energy. This biological concept encompasses movement at various levels, from whole organisms to cells and subcellular components.
Motility is observed in ...
adjustment of SG surgery, which impacts the speed and efficiency of food processing. Studies have observed a modification in the pressure of the lower esophageal sphincter and an increase in intragastric pressure post-surgery, which collectively impact the gastrointestinal motility.
Techniques:
* Hiatal Hernia
A hiatal hernia or hiatus hernia is a type of hernia in which abdominal organs (typically the stomach) slip through the diaphragm into the middle compartment of the chest. This may result in gastroesophageal reflux disease (GERD) or laryng ...
Repair. During SG, identifying and repairing a hiatal hernia (HH) is a significant step that can influence the surgery's outcome, especially concerning gastroesophageal reflux disease
Gastroesophageal reflux disease (GERD) or gastro-oesophageal reflux disease (GORD) is a chronic upper gastrointestinal disease in which stomach content persistently and regularly flows up into the esophagus, resulting in symptoms and/or ...
(GERD) management postoperatively. The procedure involves dissecting the pars flaccida
In human anatomy, the pars flaccida of tympanic membrane or Shrapnell's membrane (also known as Rivinus' ligament) is the small, triangular, flaccid portion of the tympanic membrane, or eardrum. It lies above the malleolar folds attached directly ...
to open a plane between the right crus of the liver and the esophagus
The esophagus (American English), oesophagus (British English), or œsophagus (Œ, archaic spelling) (American and British English spelling differences#ae and oe, see spelling difference) all ; : ((o)e)(œ)sophagi or ((o)e)(œ)sophaguses), c ...
, performing an intrathoracic esophageal dissection, and identifying the left crus. A hiatal hernia repair is conducted, if necessary, with a posterio
cruroplasty
using a durable suture material. This step is vital as it ensures the proper positioning of the gastroesophageal junction (GEJ) and reduces the risk of postoperative GERD
Gastroesophageal reflux disease (GERD) or gastro-oesophageal reflux disease (GORD) is a chronic upper gastrointestinal disease in which stomach content persistently and regularly flows up into the esophagus, resulting in symptoms and/or ...
by securing the stomach below the diaphragm, preventing potential acid
An acid is a molecule or ion capable of either donating a proton (i.e. Hydron, hydrogen cation, H+), known as a Brønsted–Lowry acid–base theory, Brønsted–Lowry acid, or forming a covalent bond with an electron pair, known as a Lewis ...
reflux.
* Bougie Sizing and Stapling Alongside. The insertion of a bougie during LSG is a crucial technique for guiding the creation of the gastric sleeve. The bougie, which ranges from 38 to 40 French in size, is inserted down to the pylorus
The pylorus ( or ) connects the stomach to the duodenum. The pylorus is considered as having two parts, the ''pyloric antrum'' (opening to the body of the stomach) and the ''pyloric canal'' (opening to the duodenum). The ''pyloric canal'' ends a ...
under direct visualisation, serving as a mold around which the stomach
The stomach is a muscular, hollow organ in the upper gastrointestinal tract of Human, humans and many other animals, including several invertebrates. The Ancient Greek name for the stomach is ''gaster'' which is used as ''gastric'' in medical t ...
is stapled and resected. This technique ensures that the sleeve is of uniform size and reduces the risk of narrowing a passage or obstruction post-surgery. Stapling begins 3-6 cm from the pylorus
The pylorus ( or ) connects the stomach to the duodenum. The pylorus is considered as having two parts, the ''pyloric antrum'' (opening to the body of the stomach) and the ''pyloric canal'' (opening to the duodenum). The ''pyloric canal'' ends a ...
and proceeds upwards towards the angle of His, closely aligned with the bougie to create a narrow gastric tube. The careful placement and size of the bougie are instrumental in achieving optimal sleeve shape and function, minimising complications such as leaks or strictures.
After 1-3 postoperative days, patients begin oral intake, contingent on a successful gastrografin leak test, and receive continuous metabolic monitoring. To reduce early respiratory risk, prophylactic measures such as oxygen support and ultrasound
Ultrasound is sound with frequency, frequencies greater than 20 Hertz, kilohertz. This frequency is the approximate upper audible hearing range, limit of human hearing in healthy young adults. The physical principles of acoustic waves apply ...
evaluations are employed.
Late postoperative care involves careful observation for anastomotic leaks, patient change to a clear liquid diet, and managing potential nausea
Nausea is a diffuse sensation of unease and discomfort, sometimes perceived as an urge to vomit. It can be a debilitating symptom if prolonged and has been described as placing discomfort on the chest, abdomen, or back of the throat.
Over 30 d ...
and vomiting
Vomiting (also known as emesis, puking and throwing up) is the forceful expulsion of the contents of one's stomach through the mouth and sometimes the nose.
Vomiting can be the result of ailments like food poisoning, gastroenteritis, pre ...
. After discharge, the focus shifts to dietary management, starting with a full liquid diet and gradually incorporating soft, solid foods. Monitoring includes regular check-ups for weight
In science and engineering, the weight of an object is a quantity associated with the gravitational force exerted on the object by other objects in its environment, although there is some variation and debate as to the exact definition.
Some sta ...
and blood pressure
Blood pressure (BP) is the pressure of Circulatory system, circulating blood against the walls of blood vessels. Most of this pressure results from the heart pumping blood through the circulatory system. When used without qualification, the term ...
, along with comprehensive lab tests to ensure optimal recovery.
Roux-en-Y gastric bypass surgery
Roux-en-Y gastric bypass surgery involves the creation of a new connection in the gastrointestinal tract
The gastrointestinal tract (GI tract, digestive tract, alimentary canal) is the tract or passageway of the Digestion, digestive system that leads from the mouth to the anus. The tract is the largest of the body's systems, after the cardiovascula ...
, from a smaller portion of the stomach to the middle of the small intestine
The small intestine or small bowel is an organ (anatomy), organ in the human gastrointestinal tract, gastrointestinal tract where most of the #Absorption, absorption of nutrients from food takes place. It lies between the stomach and large intes ...
.
The surgery is a permanent procedure that aims to decrease the absorption of nutrients due to the new, limited connection created. The surgery also works by affecting gut hormones, resetting hunger and satiety levels. The physically smaller stomach and increase in baseline satiety hormones help people to feel full with less food after the surgery.
This is the most commonly performed operation for weight loss in the United States, with approximately 140,000 gastric bypass procedures performed in 2005. A 2021 evidence update comparing the benefits and harms of bariatric procedures found that Roux-en-Y gastric bypass surgery and sleeve gastrectomy both effectively reduced weight and led to Type 2 diabetes remission. After five years, Roux-en-Y resulted in greater weight loss (26% compared to 19% for sleeve gastrectomy) and a 25% lower rate of diabetes relapse. However, Roux-en-Y patients had a higher likelihood of hospitalization and additional abdominal surgeries compared to sleeve gastrectomy. Though, since 2013, sleeve gastrectomy has overtaken RYGB as the most common bariatric procedure. RYGB remains one of the two most commonly performed bariatric surgeries in the world.
Gastric bypass
Gastric bypass surgery refers to a technique in which the stomach is divided into a small upper pouch and a much larger lower "remnant" pouch, where the small intestine is rearranged to connect to both. Surgeons have developed several differen ...
is the most frequently employed technique for weight reduction, the abnormal absorption in the intestines
The gastrointestinal tract (GI tract, digestive tract, alimentary canal) is the tract or passageway of the digestive system that leads from the mouth to the anus. The tract is the largest of the body's systems, after the cardiovascular system. ...
and the physical restriction of the stomach. The types of surgeries can be categorized by the effects and the changes made. Reconstruction of the small intestine to reduce the mucosal area which is used to absorb nutrients is called the Malabsorption
Malabsorption is a state arising from abnormality in absorption of food nutrients across the gastrointestinal (GI) tract. Impairment can be of single or multiple nutrients depending on the abnormality. This may lead to malnutrition and a varie ...
operation. The jejunoileal bypass (JIB) is the most traditional technique for gastric bypass. This procedure has no limitations in the flow and processing of food; it only allows the transport of nutrients from the small intestine to the surrounding areas of the intestine. The impact of weight loss is apparent and remarkable. Individuals who undergo Roux-en-Y gastric bypass (RYGB) consume fewer snacks and meals compared to those who undergo JIB. The RYGB procedure has been proved to be the most effective medical treatment for type 2 diabetes
Type 2 diabetes (T2D), formerly known as adult-onset diabetes, is a form of diabetes mellitus that is characterized by high blood sugar, insulin resistance, and relative lack of insulin. Common symptoms include increased thirst, frequent ...
and weight loss. After performing gastric bypass surgery, the two hormones related to obesity, leptin
Leptin (from Ancient Greek, Greek λεπτός ''leptos'', "thin" or "light" or "small"), also known as obese protein, is a protein hormone predominantly made by adipocytes (cells of adipose tissue). Its primary role is likely to regulate long ...
and insulin
Insulin (, from Latin ''insula'', 'island') is a peptide hormone produced by beta cells of the pancreatic islets encoded in humans by the insulin (''INS)'' gene. It is the main Anabolism, anabolic hormone of the body. It regulates the metabol ...
, fall in levels and while lose weight.
Roux-en-Y (RYGB) offers two surgical approaches for processing: an open technique or the laparoscopic
Laparoscopy () is an operation performed in the abdomen or human pelvis, pelvis using small Surgical incision, incisions (usually 0.5–1.5 cm) with the aid of a camera. The laparoscope aids diagnosis or therapeutic interventions with a few ...
technique. The majority of cases are still performed with laparoscopy. The laparoscopic approach is a safe procedure that is associated with fewer problems resulting from wound inflammation
Inflammation (from ) is part of the biological response of body tissues to harmful stimuli, such as pathogens, damaged cells, or irritants. The five cardinal signs are heat, pain, redness, swelling, and loss of function (Latin ''calor'', '' ...
.
There are three main areas of techniques for performing laparoscopic RYGB: (1) Anastomotic technique including Linear Circular stapler. 2) Alimentary limb configuration, such as Antecolic or Retrocolic and Antegastric or Retrogastric. 3) Limb-length of the bilio- pancreatic (BP) limb.
Linear stapling: this technique has two variations. 1) Perform the jejuno-jejunal (JJ) anastomosis
An anastomosis (, : anastomoses) is a connection or opening between two things (especially cavities or passages) that are normally diverging or branching, such as between blood vessels, leaf veins, or streams. Such a connection may be normal (su ...
, then act on the gastro-jejunal (GJ) anastomosis. 2) reverse the first process.
Jejuno-jejunal first: This technique is prevalent within gastric bypass surgery.
;JJ Anastomosis: In order to facilitate identification of duodenum
The duodenum is the first section of the small intestine in most vertebrates, including mammals, reptiles, and birds. In mammals, it may be the principal site for iron absorption.
The duodenum precedes the jejunum and ileum and is the shortest p ...
-jejunum (DJ) flexion
Motion, the process of movement, is described using specific anatomical terminology, anatomical terms. Motion includes movement of Organ (anatomy), organs, joints, Limb (anatomy), limbs, and specific sections of the body. The terminology used de ...
and Treitz ligaments, it will act on the Cephalic greater omentum using the laparoscopic staplers and Surgical energy device separate the mesentery
In human anatomy, the mesentery is an Organ (anatomy), organ that attaches the intestines to the posterior abdominal wall, consisting of a double fold of the peritoneum. It helps (among other functions) in storing Adipose tissue, fat and allowi ...
. It also includes measuring the Roux
Roux () is a mixture of flour and fat cooked together and used to thicken sauces. Roux is typically made from equal parts of flour and fat by weight. The flour is added to the melted fat or Cooking oil, oil on the stove top, blended until smoo ...
limb between the distal end of the binding and the chosen length. For example, if the weight index is 40, the length should be 100cm.
;Gastric pouch formation: On the lesser curve of the stomach, a window will be opened between the second and third vessel at the perigastric border. The pouch will be formed using the laparoscopic stapling device. The orogastric tube which will be removed before the first launch of the stapler horizontally. The pouch is produced over the tube with next firings in another direction. These may need the mobilisation to help further divide the stomach.
;Gastro-jejunal anastomosis: Gastrostomy
A gastrostomy is the creation of an artificial external opening into the stomach for nutritional support or gastric decompression.
Typically this would include an incision in the patient's epigastrium as part of a formal operation. When originall ...
is created at the specific angle (the part of the pouch with the least blood supply). The separate
alimentary limbs
are translocated to the pouch antecolically. Enterotomy will processed within the jejunum. At the same time, between the gastric pouch and alimentary limb, the laparoscopic stapling devices create the single firing. According to the JJ anastomosis, the anastomotic defect closes with 2 continuously absorbed sutures. Finally, 50 ml of Dilute methylene blue dye
Juan de Guillebon, better known by his stage name DyE, is a French musician. He is known for the music video of the single "Fantasy
Fantasy is a genre of speculative fiction that involves supernatural or Magic (supernatural), magical ele ...
is needed to assess leakage and ensure anastomotic integrity
Integrity is the quality of being honest and having a consistent and uncompromising adherence to strong moral and ethical principles and values.
In ethics, integrity is regarded as the honesty and Honesty, truthfulness or of one's actions. Integr ...
.
Other techniques include the Omega
Omega (, ; uppercase Ω, lowercase ω; Ancient Greek ὦ, later ὦ μέγα, Modern Greek ωμέγα) is the twenty-fourth and last letter in the Greek alphabet. In the Greek numerals, Greek numeric system/isopsephy (gematria), it has a value ...
Loop Technique and Trans-abdominal technique employ different operating approaches along with different process orders. All of them will show positive weight loss results.
The duration of the recuperation phase typically ranges from 2 to 4 weeks. The length of the period is dependent upon the self-perception of the patients and their future state of mental and physical ability. For patients to resume their normal activities, a minimum of 3-5 weeks recovery period is required. Doctors should determine the length of the recovery period based on a range of body mass index
Body mass index (BMI) is a value derived from the mass (Mass versus weight, weight) and height of a person. The BMI is defined as the human body weight, body mass divided by the square (algebra), square of the human height, body height, and is ...
.
Biliopancreatic diversion with duodenal switch
The biliopancreatic diversion with duodenal switch (BPD/DS) is a slightly less common bariatric procedure, but is increasing in use with proven efficacy for sustainable weight loss.
This procedure has multiple steps. First, a sleeve gastrectomy (see above section) is performed. This part of the procedure causes food intake restriction due to the physical reduction of the stomach size, and is permanent. Next, the stomach is then disconnected from the upper part of the small intestine
The small intestine or small bowel is an organ (anatomy), organ in the human gastrointestinal tract, gastrointestinal tract where most of the #Absorption, absorption of nutrients from food takes place. It lies between the stomach and large intes ...
and connected to a farther part of the small intestine (ileum), creating the alimentary limb. The leftover section of the far part of the small intestine is then used to make a connection that brings digestive fluids from the gallbladder
In vertebrates, the gallbladder, also known as the cholecyst, is a small hollow Organ (anatomy), organ where bile is stored and concentrated before it is released into the small intestine. In humans, the pear-shaped gallbladder lies beneath t ...
and pancreas
The pancreas (plural pancreases, or pancreata) is an Organ (anatomy), organ of the Digestion, digestive system and endocrine system of vertebrates. In humans, it is located in the abdominal cavity, abdomen behind the stomach and functions as a ...
to the alimentary limb.
Weight loss following the surgery is largely due to the alteration of gut hormones that control hunger and satiety, as well as the physical restriction of the stomach and decrease in nutrient absorption. Compared to the sleeve gastrectomy and Roux-en-Y gastric bypass, BPD/DS produces better results with lasting weight loss and resolution of type 2 diabetes.
Other related bariatric procedures
Vertical banded gastroplasty
Vertical banded gastroplasty was more commonly used in the 1980s, and is not typically performed in the 21st century.
In the vertical banded gastroplasty, a part of the stomach is permanently stapled to create a smaller, new stomach. This new stomach is physically restricted, allowing people to feel full with smaller meals. Short-term weight loss is similar to other bariatric procedures, but long-term complications may be higher.
Gastric plication
This procedure is similar to the sleeve gastrectomy surgery, but a sleeve is created by suturing
A surgical suture, also known as a stitch or stitches, is a medical device used to hold Tissue (biology), body tissues together and approximate wound edges after an injury or surgery. Application generally involves using a Sewing needle, needle w ...
, rather than physically removing stomach tissue. This allows for the natural ability of the stomach to absorb nutrients to remain intact. This procedure is reversible, is a less invasive procedure, and does not use hardware or staples.
Gastric plication significantly reduces the volume of the patient's stomach, so smaller amounts of food provide a feeling of satiety. In a 2020 review and meta-analysis, long-term weight loss was not as durable as other, more common bariatric techniques. Gastric plication has not performed as well as the sleeve gastrectomy, with the sleeve gastrectomy associated with greater weight loss and fewer complications.
Implants and devices
Adjustable gastric band
The restriction of the stomach also can be created using a silicone band, which can be adjusted by the addition or removal of saline through a port placed just under the skin, a procedure called adjustable gastric band surgery. This operation can be performed laparoscopically, and is commonly referred to as a "lap band". Weight loss is predominantly due to the restriction of nutrient intake that is created by the small gastric pouch and the narrow outlet. It is considered somewhat of a safe surgical procedure, with a mortality rate of 0.05%.
Intragastric balloon
Intragastric balloon involves placing a deflated balloon into the stomach, and then filling it to decrease the amount of gastric space, resulting in the feeling of fullness after a smaller meal. The balloon can be left in the stomach for a maximum of 6 months and results in weight loss of 3 BMI or 3–8 kg within several study ranges. Weight loss with the gastric balloon tends to be more modest than other interventions. The intragastric balloon may be used before another bariatric surgery to assist the patient in reaching a weight that is suitable for surgery but can be used repeatedly and unrelated to other procedures.
Implantable gastric stimulation
This procedure where a device similar to a heart pacemaker that is implanted by a surgeon, with the electrical leads stimulating the external surface of the stomach, was under preliminary research in 2015. Electrical stimulation is thought to modify the activity of the enteric nervous system
The enteric nervous system (ENS) is one of the three divisions of the autonomic nervous system (ANS), the others being the sympathetic nervous system (SNS) and parasympathetic nervous system (PSNS). It consists of a mesh-like system of neurons th ...
of the stomach, which is interpreted by the brain to give a sense of satiety, or fullness. Early evidence suggests that it is less effective than other forms of bariatric surgery.
Recovery
People are followed closely both before and after bariatric procedures by a healthcare team. The care team may include people in a variety of disciplines, such as social workers, dietitians, and medical weight management
Weight management comprises behaviors, techniques, and Physiology, physiological processes that contribute to a person's ability to attain and maintain a healthy Human body weight, weight. Most weight management techniques encompass long-term li ...
specialists. Follow-up after surgery is typically focused on helping avoid complications and tracking the progress toward body weight goals. Having a structure of social support in the post-operative time may be beneficial as people work through the changes that present physically and emotionally following surgery.
Dietary recommendations
Dietary restrictions after recovery from surgery depend in part on the type of surgery. In general, immediately after bariatric surgery, the person is restricted to a clear liquid diet, which includes foods such as broth
Broth, also known as bouillon (), is a savory liquid made of water in which meat, fish, or vegetables have been simmered for a short period of time. It can be eaten alone, but it is most commonly used to prepare other dishes, such as soups ...
, diluted fruit juices, or sugar-free drinks. This diet is continued until the gastrointestinal tract begins to recover approximately 2–3 weeks after surgery. The next stage provides a purée
A purée (or mash) is cooked food, usually vegetables, fruits or legumes, that has been ground, pressed, blended or sieved to the consistency of a creamy paste or liquid. Purées of specific foods are often known by specific names, e.g., appl ...
d liquid or soft-solid diet that is slightly increased in viscosity. This may consist of high protein, liquid, or soft foods such as protein shakes, soft meats, and dairy products. People in recovery are encouraged to compose their diet mainly of plant-based foods and soft proteins (1.0–1.5g/kg/day). During recovery, people must adapt to eating more slowly and avoid eating past fullness; overeating may lead to nausea and vomiting. Alcohol is avoided completely in the first 6 months to 1 year after surgery. Some people may take a daily multivitamin
A multivitamin is a preparation intended to serve as a dietary supplement with vitamins, dietary minerals, and other nutritional elements. Such preparations are available in the form of tablets, capsules, pastilles, powders, liquids, gummies, o ...
to compensate for reduced absorption of essential nutrients.
Fertility and family planning
In general, women are advised to avoid pregnancy for 12–24 months after bariatric surgery to reduce the possibility of intrauterine growth restriction or nutrient deficiency, since a person having bariatric surgery will likely undergo significant weight loss and changes in metabolism. Over many years, the rates of potential adverse maternal and fetal outcomes have been reduced for mothers following bariatric surgery.
Post-operative bariatric plastic surgery
After a person successfully loses weight following bariatric surgery, excess skin may occur. Bariatric plastic surgery procedures, sometimes called body contouring, may be an option for people wishing to remove excess skin following the large change in weight. Targeted areas include the arms, buttocks and thighs, abdomen, and breasts, with changes occurring slowly over years.
Society and culture
The rising prevalence
In epidemiology, prevalence is the proportion of a particular population found to be affected by a medical condition (typically a disease or a risk factor such as smoking or seatbelt use) at a specific time. It is derived by comparing the number o ...
of lawsuits
A lawsuit is a proceeding by one or more parties (the plaintiff or claimant) against one or more parties (the defendant) in a civil court of law. The archaic term "suit in law" is found in only a small number of laws still in effect today. T ...
related to gastric bypass surgery is a legal concern in different countries. The causes are complex, including the immature characteristics of this technology and an increasing number of patients. In the future, the number of emergent patients who have stomach reduction surgery, long-term complications, and the number of lawsuits due to non-eligible surgery will increase.
Economic implications
In the 21st century, obesity rates increased globally, and with this, a proportional rise in related diseases and complication. In the United States during 2017-20, an estimated 40% of adults were obese, up from 30% in 1999-2000. The costs of treating obesity and related conditions has a large economic impact globally. This economic impact results from direct treatment of obesity, treatment of obesity-related conditions, as well as other economic losses from decreased workforce productivity.
Bariatric surgery is cost-effective when compared to savings estimated from treatment or prevention of obesity-related conditions. Cost-effectiveness occurs at the individual level due to fewer healthcare expenses for medications, and nationally with a reduction in the overall lifetime healthcare costs.
Special populations
Adolescents
During the early 21st century, obesity among children and adolescents increased globally, as did treatment options including lifestyle changes, drug treatments, and surgical procedures. The medical complications and health concerns associated with childhood obesity
Childhood obesity is a condition where excess adipose tissue, body fat negatively affects a child's health or well-being. As methods to determine body fat directly are difficult, the diagnosis of obesity is often based on Body mass index, BMI. ...
may have short or long-term effects, with a growing concern of a potential decline in overall life expectancy
Human life expectancy is a statistical measure of the estimate of the average remaining years of life at a given age. The most commonly used measure is ''life expectancy at birth'' (LEB, or in demographic notation ''e''0, where '' ...
. Childhood obesity may affect mental health and impact eating practices.
Difficulties surrounding obesity treatment selection among children and adolescents include ethical considerations when obtaining consent from those who may be unable to do so without adult guidance or understanding the potential lasting effects of invasive procedures. Among high-quality randomized control trial data for surgical treatment of obesity, many studies are not specific to children and adolescents. Concerns for bullying
Bullying is the use of force, coercion, Suffering, hurtful teasing, comments, or threats, in order to abuse, aggression, aggressively wikt:domination, dominate, or intimidate one or more others. The behavior is often repeated and habitual. On ...
about overweight or body image exist for those with childhood obesity; self-harm among children and adolescents bullied for their weight also occurs.
Bariatric surgical procedures available to adolescents include: Roux-en-Y gastric bypass, vertical sleeve gastrectomy, and adjustable gastric banding. Multiple organizations have created guidelines for bariatric surgery indications in children and adolescents. In 2022-23, such guidelines overlapped with recommendations for potential bariatric surgical management in children and adolescents with a BMI of 40 or higher, or a BMI of 35 or higher while also experiencing related experiences.
Reviews have shown similar weight loss in adolescents following bariatric surgery as in adults. Reduction of eating disorders for several years after bariatric surgery has also been shown in adolescents after bariatric surgery. Long-term reduction in or resolution of weight-related conditions, such as diabetes and high blood pressure
Hypertension, also known as high blood pressure, is a long-term medical condition in which the blood pressure in the arteries is persistently elevated. High blood pressure usually does not cause symptoms itself. It is, however, a major ri ...
, occurred in adolescents after bariatric surgery. Long-term effects of bariatric surgery in adolescents remains under research, as of 2023.
History
Techniques for weight loss have been reported for decades, with a more formal transition to noting weight loss following surgical intervention in the 1950s when subsequent weight loss after surgical shortening of the small intestine in dogs and people was observed. Specifically, anastomosis
An anastomosis (, : anastomoses) is a connection or opening between two things (especially cavities or passages) that are normally diverging or branching, such as between blood vessels, leaf veins, or streams. Such a connection may be normal (su ...
between upper and lower portions of the small intestine to skip, or bypass, part of the small intestine led to what was called the jejuno-ileal bypass. A modified version of this procedure showed long-term improvement of lipid levels in people with known high levels of cholesterol following the procedure.
Further modification of the bypass procedure achieved weight loss in obesity, during which an anastomosis
An anastomosis (, : anastomoses) is a connection or opening between two things (especially cavities or passages) that are normally diverging or branching, such as between blood vessels, leaf veins, or streams. Such a connection may be normal (su ...
between the small intestine and upper lower intestine, known as a jejunocolic bypass, was performed. During the late 1960s, the initiation of bariatric surgery followed the development of a procedure to bypass portions of the stomach – the gastric bypass
Gastric bypass surgery refers to a technique in which the stomach is divided into a small upper pouch and a much larger lower "remnant" pouch, where the small intestine is rearranged to connect to both. Surgeons have developed several differen ...
.
Sleeve gastrectomy (SG), is one of the most popular stomach reduction surgeries and was earliest performed in 1990 as a first-stage operation of duodenal switch
The duodenal switch (DS) procedure, also known as a gastric reduction duodenal switch (GRDS), is a weight loss surgery procedure that is composed of a restrictive and a malabsorptive aspect.
The restrictive portion of the surgery involves remo ...
(DS) surgery. Patients who go through SG typically experience substantial weight loss, preventing the need for the second phase of DS.
Laparoscopic
Laparoscopy () is an operation performed in the abdomen or human pelvis, pelvis using small Surgical incision, incisions (usually 0.5–1.5 cm) with the aid of a camera. The laparoscope aids diagnosis or therapeutic interventions with a few ...
techniques revolutionized bariatric surgery, making procedures less invasive and recovery quicker. The first laparoscopic gastric bypass performed by Alan Wittgrove in 1994 exemplifies this leap in surgical innovation.The SG laparoscopic version was first performed in 1999.
Historically, the RYGBP is the best bariatric surgery for obese patients, but now being rivalled by the SG. The complication of RYGBP leads people to find less intricate and safer surgeries, the complication including internal hernias
A hernia (: hernias or herniae, from Latin, meaning 'rupture') is the abnormal exit of tissue or an organ, such as the bowel, through the wall of the cavity in which it normally resides. The term is also used for the normal development of the i ...
and anastomotic complications. Nowadays, SG has a lower risk of complication, and the mortality rate has become the more favorable option for the patients.
See also
* Revision weight loss surgery
* Endoscopic sleeve gastroplasty
References
External links
*
{{DEFAULTSORT:Bariatric surgery
Surgery
Surgery is a medical specialty that uses manual and instrumental techniques to diagnose or treat pathological conditions (e.g., trauma, disease, injury, malignancy), to alter bodily functions (e.g., malabsorption created by bariatric surgery s ...
Surgical specialties