Bisdemethoxycurcumin is a
curcuminoid
A curcuminoid is a linear diarylheptanoid, a relatively small class of plant secondary metabolites that includes curcumin, demethoxycurcumin, and bisdemethoxycurcumin, all isolated from turmeric (curcuma longa). These compounds are natural p ...
found (along with the curcuminoids
curcumin
Curcumin is a bright yellow chemical produced by plants of the ''Curcuma longa'' species. It is the principal curcuminoid of turmeric (''Curcuma longa''), a member of the ginger family, Zingiberaceae. It is sold as a herbal supplement, cos ...
and
demethoxycurcumin
Desmethoxycurcumin is a curcuminoid found in turmeric. Commercial grade curcumin contains a mixture of curcuminoids (desmethoxycurcumin 10–20%, bisdesmethoxycurcumin 5% or less).
See also
* Bis-desmethoxycurcumin
Bisdemethoxycurcumin is ...
) in
turmeric
Turmeric () is a flowering plant, ''Curcuma longa'' (), of the ginger family, Zingiberaceae, the rhizomes of which are used in cooking. The plant is a perennial, rhizomatous, herbaceous plant native to the Indian subcontinent and Southeast ...
(''Curcuma longa''), but absent in
Javanese turmeric (''Curcuma xanthorrhiza'').
Bisdemethoxycurcumin is used as a
pigment
A pigment is a colored material that is completely or nearly insoluble in water. In contrast, dyes are typically soluble, at least at some stage in their use. Generally dyes are often organic compounds whereas pigments are often inorganic comp ...
and
nutraceutical
A nutraceutical or bioceutical is a pharmaceutical alternative which claims physiological benefits. In the US, "nutraceuticals" are largely unregulated, as they exist in the same category as dietary supplements and food additives by the FDA, unde ...
with antimutagenic properties.
All three of the curcuminoids found in Curcuma longa have been shown to have antioxidant properties, but bisdemethoxycurcumin is more resistant than the others to
alkaline
In chemistry, an alkali (; from ar, القلوي, al-qaly, lit=ashes of the saltwort) is a basic, ionic salt of an alkali metal or an alkaline earth metal. An alkali can also be defined as a base that dissolves in water. A solution of a ...
degradation.
It was found to be effective in sensitizing PC cells resistance against gemcitabine.
See also
*
Curcumin
Curcumin is a bright yellow chemical produced by plants of the ''Curcuma longa'' species. It is the principal curcuminoid of turmeric (''Curcuma longa''), a member of the ginger family, Zingiberaceae. It is sold as a herbal supplement, cos ...
*
Desmethoxycurcumin
Desmethoxycurcumin is a curcuminoid found in turmeric. Commercial grade curcumin contains a mixture of curcuminoids (desmethoxycurcumin 10–20%, bisdesmethoxycurcumin 5% or less).
See also
* Bis-desmethoxycurcumin
* Curcumin
Curcumin is ...
References
External links
*
Curcuminoids
Food colorings
Phenolic dietary antioxidants
Vinylogous carboxylic acids
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