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Bioastronautics is a specialty area of
biological Biology is the scientific study of life and living organisms. It is a broad natural science that encompasses a wide range of fields and unifying principles that explain the structure, function, growth, origin, evolution, and distribution of ...
and astronautical research which encompasses numerous aspects of biological, behavioral, and medical concern governing humans and other living organisms in outer space; and includes the design of space vehicle payloads,
space habitat A space settlement (also called a space habitat, spacestead, space city or space colony) is a Human settlement, settlement in outer space, sustaining more extensively Space habitat (facility), habitation facilities in space than a general space ...
s, and life-support systems. In short, it spans the study and support of life in
space Space is a three-dimensional continuum containing positions and directions. In classical physics, physical space is often conceived in three linear dimensions. Modern physicists usually consider it, with time, to be part of a boundless ...
. Bioastronautics includes many similarities with its sister discipline astronautical hygiene; they both study the hazards that humans may encounter during a space flight. However, astronautical hygiene differs in many respects e.g. in this discipline, once a hazard is identified, the exposure risks are then assessed and the most effective measures determined to prevent or control exposure and thereby protect the health of the astronaut. Astronautical hygiene is an applied scientific discipline that requires knowledge and experience of many fields including bioastronautics, space medicine, ergonomics etc. The skills of astronautical hygiene are already being applied for example, to characterise Moon dust and design the measures to mitigate exposure during lunar exploration, to develop accurate chemical monitoring techniques and use the results in the setting SMACs. Of particular interest from a biological perspective are the effects of reduced gravitational force felt by inhabitants of spacecraft. Often referred to as "
microgravity Weightlessness is the complete or near-complete absence of the sensation of weight, i.e., zero apparent weight. It is also termed zero g-force, or zero-g (named after the g-force) or, incorrectly, zero gravity. Weight is a measurement of the fo ...
", the lack of sedimentation, buoyancy, or convective flows in fluids results in a more quiescent cellular and intercellular environment primarily driven by chemical gradients. Certain functions of organisms are mediated by gravity, such as
gravitropism Gravitropism (also known as geotropism) is a coordinated process of differential growth by a plant in response to gravity pulling on it. It also occurs in fungi. Gravity can be either "artificial gravity" or natural gravity. It is a general feat ...
in plant roots and negative gravitropism in plant stems, and without this stimulus growth patterns of organisms onboard spacecraft often diverge from their terrestrial counterparts. Additionally, metabolic energy normally expended in overcoming the force of gravity remains available for other functions. This may take the form of accelerated growth in organisms as diverse as worms like '' C. elegans'' to miniature
parasitoid wasp Parasitoid wasps are a large group of hymenopteran Superfamily (zoology), superfamilies, with all but the wood wasps (Orussoidea) being in the wasp-waisted Apocrita. As parasitoids, they lay their eggs on or in the bodies of other arthropods, ...
s such as ''Spangia endius''. It may also be used in the augmented production of secondary metabolites such as the vinca alkaloids
Vincristine Vincristine, also known as leurocristine and sold under the brand name Oncovin among others, is a chemotherapy medication used to treat a number of types of cancer. This includes acute lymphocytic leukemia, acute myeloid leukemia, Hodgkin lym ...
and Vinblastine in the rosy periwinkle ('' Catharanthus roseus''), whereby space grown specimens often have higher concentrations of these constituents that on earth are present in only trace amounts.


Engineering considerations

From an engineering perspective, facilitating the delivery and exchange of air, food, and water, and the processing of waste products is also challenging. The transition from expendable physicochemical methods to sustainable bioregenerative systems that function as a robust miniature ecosystem is another goal of bioastronautics in facilitating long duration space travel. Such systems are often termed Closed Ecological Life Support Systems (CELSS).


Medical considerations

From a medical perspective, long duration space flight also has physiological impacts on astronauts. Accelerated bone decalcification, similar to
osteopenia Osteopenia, known as "low bone mass" or "low bone density", is a condition in which bone mineral density is low. Because their bones are weaker, people with osteopenia may have a higher risk of fractures, and some people may go on to develop o ...
and
osteoporosis Osteoporosis is a systemic skeletal disorder characterized by low bone mass, micro-architectural deterioration of bone tissue leading to more porous bone, and consequent increase in Bone fracture, fracture risk. It is the most common reason f ...
on Earth, is just one such condition. Another serious concern is the effects of space travel upon the kidneys. Current estimates of these effects upon the kidneys indicates that unless some kind of effective additional remedial technology against kidney damage is employed, astronauts who have been exposed to micro-gravity, reduced gravity, and Galactic radiation for 3 years or so on a Mars mission may have to return to Earth while attached to dialysis machines. The study of the potential effects of space travel is useful not only for advancing methods of the safe habitation of space, and the travel through space, but also in uncovering ways to more effectively treat closely related terrestrial ailments.


NASA's Bioastronautics library

NASA The National Aeronautics and Space Administration (NASA ) is an independent agencies of the United States government, independent agency of the federal government of the United States, US federal government responsible for the United States ...
's
Johnson Space Center The Lyndon B. Johnson Space Center (JSC) is NASA's center for human spaceflight in Houston, Texas (originally named the Manned Spacecraft Center), where human spaceflight training, research, and flight controller, flight control are conducted. ...
in Houston, Texas maintains a Bioastronautics Library. The one-room facility provides a collection of textbooks, reference books, conference proceedings, and academic journals related to bioastronautics topics. Because the library is located within secure government property (not part of
Space Center Houston Space Center Houston is a science museum that serves as the official visitor center of NASA Johnson Space Center in Houston, Texas. It was designated a Smithsonian Affiliate museum in 2014. The organization is owned by NASA, and operated unde ...
, the official visitors center of JSC), it is not generally accessible to the public.


See also

* Effect of spaceflight on the human body * Life support system * Space habitation * Locomotion in space * Reduced muscle mass, strength and performance in space * Space food * Astronautical hygiene * Spaceflight radiation carcinogenesis * Space medicine * Sex in space *
Space tourism Space tourism is human space travel for recreational purposes. There are several different types of space tourism, including orbital, suborbital and lunar space tourism. Tourists are motivated by the possibility of viewing Earth from space, ...
* Space-based economy * List of spaceflight-related accidents and incidents * Writing in space * Space art#Art in space * Religion in space *
Organisms at high altitude Organisms can live at high altitude, either on land, in water, or while flying. Decreased oxygen availability and decreased temperature make life at such altitudes challenging, though many species have been successfully evolutionary adaptation, ...
*
Astrobiology Astrobiology (also xenology or exobiology) is a scientific field within the List of life sciences, life and environmental sciences that studies the abiogenesis, origins, Protocell, early evolution, distribution, and future of life in the univ ...
* Astrobotany * Plants in space


References


External links

*Harvard-MIT Health Sciences and Technology - Bioastronautics Training Program (HST-Bioastro

*
NASA The National Aeronautics and Space Administration (NASA ) is an independent agencies of the United States government, independent agency of the federal government of the United States, US federal government responsible for the United States ...
's Bioastronautics Roadma

*
University of Colorado at Boulder The University of Colorado Boulder (CU Boulder, CU, or Colorado) is a Public university, public research university in Boulder, Colorado, United States. Founded in 1876, five months before Colorado became a Federated state, state, it is the fla ...
Bioastronautics Research Grou

*The American Society for Gravitational and Space Biology (ASGSB

*1965 radio series titled ''Their Other World'', 13 half-hour episodes with typed transcrip

{{Space medicine, state=expanded Aviation medicine Human spaceflight Biological engineering Space medicine