BioCity Nottingham
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BioCity Nottingham is a bioscience
science park A science park (also called a "university research park", "technology park", "technopark", "technopolis", "technopole", or a "science and technology park" TP is defined as being a property-based development that accommodates and fosters ...
in central
Nottingham Nottingham ( , East Midlands English, locally ) is a City status in the United Kingdom, city and Unitary authorities of England, unitary authority area in Nottinghamshire, East Midlands, England. It is located south-east of Sheffield and nor ...
in the United Kingdom. It is the UK's largest bioscience innovation and incubation centre, now run b
Pioneer Group
a specialist life sciences real estate and venture building company.


History

On Sunday 24 April 1983 there was an explosion at the former Boots site. Due to Flosequinan, known as Manoplax, having commercial difficulties, Boots Pharmaceuticals was bought by
Knoll Pharmaceuticals Knoll Pharmaceuticals was a drug development company founded by Albert Knoll and Hans Knoll in Germany in 1886. The company was taken over by German BASF in 1975, which sold it to Abbott Laboratories on 30 June 2002 for $6.9 billion. It was the d ...
, part of BASF in March 1995, for £840m. Sibutramine was being developed by Boots at the time. 100 research jobs were cut at Beeston, and 165 at the site in October 1995. On Tuesday 3 September 1996 BASF chairman Jürgen F. Strube visited the Nottingham site. BASF decided to sell the site in April 2000. In 2002, laboratories and office space were donated to
Nottingham Trent University Nottingham Trent University (NTU) is a public research university located in Nottingham, England. Its origins date back to 1843 with the establishment of the Nottingham School of Design, Nottingham Government School of Design, which still opera ...
by BASF. Biocity was founded in September 2003 by the University of Nottingham, Nottingham Trent University (NTU) and the
East Midlands Development Agency east midlands development agency, abbreviated emda, was the regional development agency for the East Midlands region of England formed in 1999 and dissolved in 2012. Structure and function emda’s office was located next to a Premier Inn, BBC ...
(which was based close to BioCity). Biocity's premises were developed from the building donated by BASF. Phase 1 was completed in March 2004, providing of space, then Phase 2 in March 2006 provided . When Phase 3 of the development was completed in October 2008, with , funding from emda also finished.


Associated Boots site

Boots had an animal testing site at the priory at
Thurgarton Thurgarton is a small Village#United Kingdom, village in rural Nottinghamshire, England. The village is close to Southwell, Nottinghamshire, Southwell, and Newark-on-Trent and still within commuting distance to Nottingham. It is served by Thur ...
, the Thurgarton Research Station, in Nottinghamshire from 1947, set up by biochemist Sir Jack Drummond, which Knoll bought, and moved out in April 1996. An animal rights organisation, the Boots Action Committee, had protested at both sites. On Sunday 20 June 1982 the ALF entered the Thurgarton site and stole 13 Beagle dogs. In 1984 animal rights protesters had tampered with Boots shampoo products. On Saturday 3 November 1990 a group of the ALF broke into the Thurgarton site and stole eight Beagle dogs. The group appeared at Newark magistrates on Tuesday 13 November 1990. 43 animal rights protesters were arrested at Thurgarton on 12 November 1990, but criminal charges were dropped. Boots Properties decided to sell the Thurgarton site in August 1997 for £1m.


Background

Nottingham has a history of bioscience research done at the University of Nottingham, Nottingham Trent University and by
Boots A boot is a type of footwear. Most boots mainly cover the foot and the ankle, while some also cover some part of the lower calf. Some boots extend up the leg, sometimes as far as the knee or even the hip. Most boots have a heel that is clearl ...
, Britain's largest retail
pharmacy Pharmacy is the science and practice of discovering, producing, preparing, dispensing, reviewing and monitoring medications, aiming to ensure the safe, effective, and affordable use of medication, medicines. It is a miscellaneous science as it ...
company, which is based in
Dunkirk Dunkirk ( ; ; ; Picard language, Picard: ''Dunkèke''; ; or ) is a major port city in the Departments of France, department of Nord (French department), Nord in northern France. It lies from the Belgium, Belgian border. It has the third-larg ...
/ Beeston. Although Boots no longer engages in drug discovery,
Ibuprofen Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID) that is used to relieve pain, fever, and inflammation. This includes dysmenorrhea, painful menstrual periods, migraines, and rheumatoid arthritis. It can be taken oral administration, ...
(iso-butyl-propanoic-phenolic acid) was created by a team of Boots scientists including Stewart Adams and John Nicholson. In November 2013 work on ibuprofen was recognised by the erection of a Royal Society of Chemistry blue plaque on the site of the original laboratory where the painkiller was developed. The plaque reads: In March 2005 Nottingham was named as a Science City; the other 5 Science Cities were
Birmingham Birmingham ( ) is a City status in the United Kingdom, city and metropolitan borough in the metropolitan county of West Midlands (county), West Midlands, within the wider West Midlands (region), West Midlands region, in England. It is the Lis ...
,
Bristol Bristol () is a City status in the United Kingdom, cathedral city, unitary authority area and ceremonial county in South West England, the most populous city in the region. Built around the River Avon, Bristol, River Avon, it is bordered by t ...
,
York York is a cathedral city in North Yorkshire, England, with Roman Britain, Roman origins, sited at the confluence of the rivers River Ouse, Yorkshire, Ouse and River Foss, Foss. It has many historic buildings and other structures, such as a Yor ...
,
Newcastle Newcastle usually refers to: *Newcastle upon Tyne, a city and metropolitan borough in Tyne and Wear, England, United Kingdom *Newcastle-under-Lyme, a town in Staffordshire, England, United Kingdom *Newcastle, New South Wales, a metropolitan area ...
and
Manchester Manchester () is a city and the metropolitan borough of Greater Manchester, England. It had an estimated population of in . Greater Manchester is the third-most populous metropolitan area in the United Kingdom, with a population of 2.92&nbs ...
.


Construction

An earlier research site, for antibiotics and fermentation, had been opened in 1956 next to an antibiotics factory of Boots in Beeston. On Monday 4 April 1955, Boots acquired 3,675 sq ft of land for the research centre for £30,000, from Nottingham City Council. Construction was underway by November 1957. The £750,000 seven-storey Chemical Sciences Research Laboratory had been built by February 1958, and opened on Tuesday 22 September 1959, with 24 laboratories. The 1959 building was built by William Moss and Sons, of Queens Road in Loughborough. There was no official opening ceremony, with 88,000 sq ft of buildings. It had a 200-seat lecture theatre, and a radioisotope unit. The site was to also research
bacteriology Bacteriology is the branch and specialty of biology that studies the Morphology (biology), morphology, ecology, genetics and biochemistry of bacteria as well as many other aspects related to them. This subdivision of microbiology involves the iden ...
. There was a large stained glass of 16ft by 14 ft panel in the entrance to the building, designed by
Tony Hollaway Antony Hollaway (8 March 1928 – 9 August 2000) was a British stained glass designer, craftsman and sculptor. Biography Hollaway was born and grew up in Dorset and educated there at Poole Grammar School and Bournemouth College of Art, followe ...
. There was a 8ft by 15ft mural designed by 24 year old Peter Spring, of the Nottingham School of Architecture. The nearby Trent House, Nottingham began construction around May 1959, to be finished in 1961. A new £25m block was added in 1985. In November 1990, Boots unveiled plans to redevelop the nearby area as a business park,with a hotel, to cost £150m on the 18 acre site. The current site of
BBC East Midlands BBC East Midlands is the BBC English Region covering Derbyshire (except High Peak, Chesterfield, North East Derbyshire and the northern areas of the Derbyshire Dales), Leicestershire, Nottinghamshire (except Bassetlaw), Rutland, South Kest ...
was to be a Boots-owned hotel and conference centre.


Structure

It is situated in former
BASF BASF SE (), an initialism of its original name , is a European Multinational corporation, multinational company and the List of largest chemical producers, largest chemical producer in the world. Its headquarters are located in Ludwigshafen, Ge ...
buildings, which previously were used by Boots as research laboratories. The site on Pennyfoot Street, between the A60 and A612, is for bioscience SMEs. The University of Nottingham has the largest collaboration with companies at BioCity, with a few having links with NTU. There are three buildings – * Innovation Centre Building * Stewart Adams Building – named after Dr Stewart Adams OBE, who led the team at Boots (with John Nicholson) that discovered Ibuprofen, a
non-steroidal anti-inflammatory drug Non-steroidal anti-inflammatory drugs (NSAID) are members of a therapeutic drug class which reduces pain, decreases inflammation, decreases fever, and prevents blood clots. Side effects depend on the specific drug, its dose and duration of ...
, in 1963 * Laurus Building In January 2012 BioCity opened a second site, BioCity Scotland, resulting from the acquisition of a former MSD research facility near Glasgow.


Heads of research

* Eric Edward Cliffe (1932-2020) 1980s, attended
Jesus College, Cambridge Jesus College is a Colleges of the University of Cambridge, constituent college of the University of Cambridge. Jesus College was established in 1496 on the site of the twelfth-century Benedictine nunnery of St Radegund's Priory, Cambridge, St ...
E E Cliffe
/ref>


See also

* Chesterford Park Research Station, former
Fisons Fisons plc was a British Multinational corporation, multinational pharmaceutical, scientific instruments and horticultural chemicals company headquartered in Ipswich, United Kingdom. It was listed on the London Stock Exchange and was once a cons ...
site * Sheffield Bioincubator * London Bioscience Innovation Centre *
Francis Crick Institute The Francis Crick Institute (formerly the UK Centre for Medical Research and Innovation) is a biomedical research centre in London, which was established in 2010 and opened in 2016. The institute is a partnership between Cancer Research UK, Im ...
* Creative Quarter, Nottingham


References


External links


BioCity Nottingham

Science City Nottingham

UKSPA



CPMG Architects - Discovery Building at BioCity


News items


Laurus Building opens in October 2008


Video clips


Glen Crocker

Nottingham Science – Laurus Building
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