Bilirubin di-glucuronide is a conjugated form of
bilirubin
Bilirubin (BR) (Latin for "red bile") is a red-orange compound that occurs in the normal catabolic pathway that breaks down heme in vertebrates. This catabolism is a necessary process in the body's clearance of waste products that arise from the ...
formed in bilirubin metabolism. The
hydrophilic
A hydrophile is a molecule or other molecular entity that is attracted to water molecules and tends to be dissolved by water.Liddell, H.G. & Scott, R. (1940). ''A Greek-English Lexicon'' Oxford: Clarendon Press.
In contrast, hydrophobes are ...
character of bilirubin diglucuronide enables it to be water-soluble. It is pumped across the hepatic canalicular membrane into the
bile
Bile (from Latin ''bilis''), or gall, is a dark-green-to-yellowish-brown fluid produced by the liver of most vertebrates that aids the digestion of lipids in the small intestine. In humans, bile is produced continuously by the liver (liver b ...
by the transporter
MRP2 MRP2 may refer to:
* Multidrug resistance-associated protein 2
* Manufacturing resource planning (''MRP2'' or ''MRP II'')
{{Letter-NumberCombDisambig ...
.
See also
*
Bilirubin mono-glucuronide
References
Metabolism
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