3-Hydroxyvaleric acid (3-hydroxypentanoic acid) is the organic compound with the formula . It is one of the
hydroxypentanoic acids. It is made from
odd carbon fatty acids in the liver and rapidly enters the brain. As opposed to 4-carbon ketone bodies, 3-hydroxyvaleric acid is
anaplerotic, meaning it can refill the pool of
TCA cycle
The citric acid cycle—also known as the Krebs cycle, Szent–Györgyi–Krebs cycle, or TCA cycle (tricarboxylic acid cycle)—is a series of chemical reaction, biochemical reactions that release the energy stored in nutrients through acetyl-Co ...
intermediates. The triglyceride
triheptanoin
Triheptanoin, sold under the brand name Dojolvi, is a medication for the treatment of children and adults with molecularly confirmed long-chain fatty acid oxidation disorders (LC-FAOD).
The most common adverse reactions include abdominal pain, ...
is used clinically to produce 3-hydroxyvalerate (the
carboxylate
In organic chemistry, a carboxylate is the conjugate base of a carboxylic acid, (or ). It is an anion, an ion with negative charge.
Carboxylate salts are salts that have the general formula , where M is a metal and ''n'' is 1, 2,... ...
form).
Properties
*Solubility in
water
Water is an inorganic compound with the chemical formula . It is a transparent, tasteless, odorless, and Color of water, nearly colorless chemical substance. It is the main constituent of Earth's hydrosphere and the fluids of all known liv ...
: 784.8 g/L at 25 °C (estimated)
References
{{DEFAULTSORT:Hydroxyvaleric acid, 3-
Beta hydroxy acids