Bengt A. Robertson was a Swedish physician and perinatal pathologist. Robertson was primarily known for the development of the synthetic
lung surfactant
Pulmonary surfactant is a surface-active complex of phospholipids and proteins formed by type II alveolar cells. The proteins and lipids that make up the surfactant have both hydrophilic and hydrophobic regions. By adsorbing to the air-water ...
known as
Corusurf that brought relief to very small babies suffering from
infant respiratory distress syndrome
Infantile respiratory distress syndrome (IRDS), also called respiratory distress syndrome of newborn, or increasingly surfactant deficiency disorder (SDD), and previously called hyaline membrane disease (HMD), is a syndrome in premature infants c ...
(RDS).
From 1974 to 2000 he was the director of the division for experimental perinatal pathology in the department of women and child Health at the Karolinska Institute.
In 1996 he was awarded the
King Faisal International Prize in Medicine together with
Tetsurō Fujiwara
Tetsurō Fujiwara is a Japanese physician. In 1996 he was awarded the King Faisal International Prize in Medicine together with Bengt Robertson for contributions to the understanding of neonatal medicine
Neonatology is a subspecialty of ...
for contributions to the understanding of
neonatal medicine.
Life
Robertson was born and grew up in Stockholm. As a child he attended the
Södra Latins Gymnasium
Södra Skogsägarna, trading as Södra, is a forestry cooperative based in Växjö, Sweden. More than 52,000 forest owners in southern Sweden are members of the economic association that is Södra. They own just over half of all privately owned fo ...
in the
Södermalm
Södermalm, often shortened to just Söder, is a district and island in central Stockholm.
Overview
The district covers the large island of the same name (formerly called ''Åsön''). Although Södermalm usually is considered an island, wa ...
area of Stockholm, leaving in 1953.
Having decided to become a physician, Robertson attended the
Karolinska Institute
The Karolinska Institute (KI; sv, Karolinska Institutet; sometimes known as the (Royal) Caroline Institute in English) is a research-led medical university in Solna within the Stockholm urban area of Sweden. The Karolinska Institute is consis ...
, a medical universiy and graduated
Master of Science in Medicine (Swedish: Läkarexamen) in 1960.
Robertson followed the MD with a
Doctor of Philosophy
A Doctor of Philosophy (PhD, Ph.D., or DPhil; Latin: or ') is the most common degree at the highest academic level awarded following a course of study. PhDs are awarded for programs across the whole breadth of academic fields. Because it is ...
degree and was awarded a doctorate in 1968. His thesis was titled: "The intrapulmonary arterial pattern in normal infancy and in transposition of the great arteries".
Career
From 1974 to 2000 he was director the Division of Experimental Perinatal Pathology at the Karolinska Institute.
Surfactant Research
When Robertson was a visiting professor at the University of Toronto in the department of pathology, he met the
obstetrician
Obstetrics is the field of study concentrated on pregnancy, childbirth and the postpartum period. As a medical specialty, obstetrics is combined with gynecology under the discipline known as obstetrics and gynecology (OB/GYN), which is a surg ...
Göran Enhörning
Göran or Jöran (both pronounced ) is the Swedish form of George, not to be confused with the Slavic Goran.
Notable people with the name include:
*Göran Andersson, Swedish sport sailor
*Göran Bror Benny Andersson Swedish musician, compose ...
who at the time was based at the
Toronto Western Hospital
The Toronto Western Hospital (TWH) is a major research and teaching hospital in Toronto, Ontario, Canada. It is part of the University Health Network (UHN). It has 256 beds, with 46,000 visits to its emergency department annually. It is known fo ...
. Enhörning who was also from Stockholm like Robertson, would became his principle collaborator.
In January 1964 the first preliminary study on the use of synthetic surfactant beta-gamma-dipalmitoyl-L-alpha-lecithin (DPL) that was delivered by nebulizer to 11 infants with RDS.
Two trials were conducted in that used nebulised synthetic surfactant that was composed of synthetic
dipalmitoylphosphatidylcholine
Dipalmitoylphosphatidylcholine (DPPC) is a phospholipid (and a lecithin) consisting of two C16 palmitic acid groups attached to a phosphatidylcholine head-group.
It is the main constituent of pulmonary surfactants, which reduces the work of breath ...
(DPPC), showed negative results in the treatment of RDS.
In 1972, Bengt and Enhörning developed research to discover the reasons for the failure of nebulised synthetic surfactant. They showed that when natural surfactant was installed directly into the
trachea
The trachea, also known as the windpipe, is a cartilaginous tube that connects the larynx to the bronchi of the lungs, allowing the passage of air, and so is present in almost all air-breathing animals with lungs. The trachea extends from th ...
of premature rabbits took place, normal lung expansion was achieved, and the animals survived.
In the autumn of 1984, Bengt became the leader of a group of neonatologist and surfactant researchers, known as the "The Collaborative European Multicenter
Study Group", who were formed to test Curosurf in the first large international multicentre clinical trial.
Honours
Robertson received many honours throughout his life. In 1996, he was first recognised when he was awarded the
King Faisal International Prize
The King Faisal Prize ( ar, جائزة الملك فيصل, formerly King Faisal International Prize), is an annual award sponsored by King Faisal Foundation presented to "dedicated men and women whose contributions make a positive difference". T ...
.
Two years later in 1998, Robertson along with
Tore Curstedt
Tore Curstedt (born 1946 in Piteå) is a Swedish physician. Curstedt is primarily known for the development of the synthetic lung surfactant known as Corusurf along with Bengt Robertson
Bengt A. Robertson was a Swedish physician and perinatal ...
was awarded the
Hilda and Alfred Eriksson Prize by the
Royal Swedish Academy of Sciences. In 2002, he was awarded the
Erich Saling Maternité Prize given by the
European Association of Perinatal Medicine
European, or Europeans, or Europeneans, may refer to:
In general
* ''European'', an adjective referring to something of, from, or related to Europe
** Ethnic groups in Europe
** Demographics of Europe
** European cuisine, the cuisines of Europe a ...
. This was followed in 2004 with the awarding of the
Lars Werkö Prize
Lars is a common male name in Scandinavian countries.
Origin
''Lars'' means "from the city of Laurentum". Lars is derived from the Latin name Laurentius, which means "from Laurentum" or "crowned with laurel".
A homonymous Etruscan name was bo ...
by the
Swedish Heart Lung Foundation
Swedish or ' may refer to:
Anything from or related to Sweden, a country in Northern Europe. Or, specifically:
* Swedish language, a North Germanic language spoken primarily in Sweden and Finland
** Swedish alphabet, the official alphabet used by ...
along with Tore Curstedt.
In 2023, Robertson was awarded the singular honour of having an award named after himself, when the
European Academy of Paediatric Societies created the
Bengt Robertson Award
Bengt may refer to:
People In arts, entertainment and media Actors
* Bengt Djurberg (1898–1941), Swedish actor and singer
* Bengt Ekerot (1920–1971), Swedish actor and director
* Bengt Eklund (1925–1998), Swedish actor
* Bengt Logardt (1914 ...
for research into the neonatal lung.
Publications
*
*
References
Citation
Bibliography
*
Biography articles needing translation from German Wikipedia
1935 births
2008 deaths
20th-century Swedish physicians
Karolinska Institute alumni
{{Sweden-scientist-stub