Basopenia (or basocytopenia) is a form of
agranulocytosis
Agranulocytosis, also known as agranulosis or granulopenia, is an acute condition involving a severe and dangerous lowered white blood cell count ( leukopenia, most commonly of neutrophils) and thus causing a neutropenia in the circulating blood. ...
associated with a deficiency of
basophil
Basophils are a type of white blood cell. Basophils are the least common type of granulocyte, representing about 0.5% to 1% of circulating white blood cells. However, they are the largest type of granulocyte. They are responsible for inflammato ...
s.
It has been proposed as an indicator of
ovulation
Ovulation is the release of eggs from the ovaries. In women, this event occurs when the ovarian follicles rupture and release the secondary oocyte ovarian cells. After ovulation, during the luteal phase, the egg will be available to be fertilize ...
.
It is difficult to detect without
flow cytometry
Flow cytometry (FC) is a technique used to detect and measure physical and chemical characteristics of a population of cells or particles.
In this process, a sample containing cells or particles is suspended in a fluid and injected into the fl ...
, because normal levels are so low.
It can be defined as less than 0.01 x 10
9 / L.
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Associated conditions
* Hereditary absence of basophils (very rare)
* Elevated levels of glucocorticoids
* Hyperthyroidism or treatment with thyroid hormones
* Ovulation
* Hypersensitivity reactions
:*
urticaria
Hives, also known as urticaria, is a kind of skin rash with red, raised, itchy bumps. Hives may burn or sting. The patches of rash may appear on different body parts, with variable duration from minutes to days, and does not leave any long-lasti ...
:*Anaphylaxis
:*Drug-induced reactions
* Leukocytosis (in association with diverse disorders)
References
External links
Monocyte and granulocyte disorders
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