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Proteasome Proteasomes are essential protein complexes responsible for the degradation of proteins by proteolysis, a chemical reaction that breaks peptide bonds. Enzymes that help such reactions are called proteases. Proteasomes are found inside all e ...
endopeptidase complex (, ''ingensin'', ''macropain'', ''multicatalytic endopeptidase complex'', ''prosome'', ''multicatalytic proteinase (complex)'', ''MCP'', ''proteasome'', ''large multicatalytic protease'', ''proteasome organelle'', ''alkaline protease'', ''26S protease'', ''tricorn proteinase'', ''tricorn protease'') is an
enzyme An enzyme () is a protein that acts as a biological catalyst by accelerating chemical reactions. The molecules upon which enzymes may act are called substrate (chemistry), substrates, and the enzyme converts the substrates into different mol ...
. This enzyme catalyses the following
chemical reaction A chemical reaction is a process that leads to the chemistry, chemical transformation of one set of chemical substances to another. When chemical reactions occur, the atoms are rearranged and the reaction is accompanied by an Gibbs free energy, ...
: Cleavage of
peptide bond In organic chemistry, a peptide bond is an amide type of covalent chemical bond linking two consecutive alpha-amino acids from C1 (carbon number one) of one alpha-amino acid and N2 (nitrogen number two) of another, along a peptide or protein cha ...
s with very broad specificity This 20-S protein is composed of 28 subunits arranged in four rings of seven.


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* {{Portal bar, Biology, border=no EC 3.4.25