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A lower gastrointestinal series is a medical procedure used to examine and diagnose problems with the human colon of the
large intestine The large intestine, also known as the large bowel, is the last part of the gastrointestinal tract and of the Digestion, digestive system in tetrapods. Water is absorbed here and the remaining waste material is stored in the rectum as feces befor ...
.
Radiographs Radiography is an imaging technique using X-rays, gamma rays, or similar ionizing radiation and non-ionizing radiation to view the internal form of an object. Applications of radiography include medical ("diagnostic" radiography and "therapeu ...
(
X-ray An X-ray (also known in many languages as Röntgen radiation) is a form of high-energy electromagnetic radiation with a wavelength shorter than those of ultraviolet rays and longer than those of gamma rays. Roughly, X-rays have a wavelength ran ...
pictures) are taken while
barium sulfate Barium sulfate (or sulphate) is the inorganic compound with the chemical formula Ba SO4. It is a white crystalline solid that is odorless and insoluble in water. It occurs in nature as the mineral barite, which is the main commercial source of ...
, a
radiocontrast agent Radiocontrast agents are substances used to enhance the visibility of internal structures in X-ray-based imaging techniques such as computed tomography (contrast CT), projectional radiography, and fluoroscopy. Radiocontrast agents are typically iod ...
, fills the colon via an
enema An enema, also known as a clyster, is the rectal administration of a fluid by injection into the Large intestine, lower bowel via the anus.Cullingworth, ''A Manual of Nursing, Medical and Surgical'':155 The word ''enema'' can also refer to the ...
through the
rectum The rectum (: rectums or recta) is the final straight portion of the large intestine in humans and some other mammals, and the gut in others. Before expulsion through the anus or cloaca, the rectum stores the feces temporarily. The adult ...
. The term barium enema usually refers to a lower gastrointestinal series, although enteroclysis (an
upper gastrointestinal series An upper gastrointestinal series, also called a barium swallow, barium study, or barium meal, is a series of radiographs used to examine the gastrointestinal tract for abnormalities. A contrast medium, usually a radiocontrast agent such as bariu ...
) is often called a small bowel barium enema.


Purpose

For any suspected large bowel disease,
colonoscopy Colonoscopy () or coloscopy () is a medical procedure involving the Endoscopy, endoscopic examination of the large bowel (colon) and the distal portion of the small bowel. This examination is performed using either a Charge-coupled device, CCD ...
is the investigation of choice because tissue sample can be taken for investigation.
Virtual colonoscopy Virtual colonoscopy (VC, also called CT colonography or CT pneumocolon) is the use of CT scanning or magnetic resonance imaging (MRI) to produce two- and three-dimensional images of the colon (large intestine), from the lowest part, the rectum, ...
(also known as CT colonography) is another preferred investigation, provided that facilities and expertise are available. Virtual colonoscopy also avoids the risk of total blockage of any stricture in the large bowel due to barium impaction. Some conditions are absolutely contraindicated for barium enema namely:
toxic megacolon Toxic megacolon is an acute form of colonic distension. It is characterized by a very dilated Colon (anatomy), colon (megacolon), accompanied by abdominal distension (bloating), and sometimes fever, abdominal pain, or Shock (circulatory), shock. ...
, pseudomembranous colitis, and recent history rigid endoscopy of the large bowel in the past five days and recent history of flexible endoscopy in the past 24 hours. This is because, rigid endoscopy tends to use larger biopsy forceps to take tissue samples from the bowel wall while flexible endoscopy uses small biopsy forceps to take superficial samples. For those with incomplete bowel preparation, the subject can return the next day or the day after next to repeat the procedure. If barium meal was performed recently, then it is advised to wait for another seven to ten days before repeating the procedure. Some frail subject may not be suitable for barium meal. Barium enemas are most commonly used to check bowel health; they can help diagnose and evaluate the extent of inflammatory bowel diseases such as
ulcerative colitis Ulcerative colitis (UC) is one of the two types of inflammatory bowel disease (IBD), with the other type being Crohn's disease. It is a long-term condition that results in inflammation and ulcers of the colon and rectum. The primary sympto ...
and
Crohn's disease Crohn's disease is a type of inflammatory bowel disease (IBD) that may affect any segment of the gastrointestinal tract. Symptoms often include abdominal pain, diarrhea, fever, abdominal distension, and weight loss. Complications outside of the ...
. Polyps can be seen, though not removed during the exam like with a
colonoscopy Colonoscopy () or coloscopy () is a medical procedure involving the Endoscopy, endoscopic examination of the large bowel (colon) and the distal portion of the small bowel. This examination is performed using either a Charge-coupled device, CCD ...
—they may be cancerous. Other problems such as
diverticulosis Diverticulosis is the condition of having multiple pouches (diverticulum, diverticula) in the colon (anatomy), colon that are not inflamed. These are outpockets of the colonic mucosa and submucosa through weaknesses of muscle layers in the col ...
(small pouches formed on the colon wall that can become inflamed) and intussusception can be found (and in certain cases the test itself can treat intussusception). An acute
appendicitis Appendicitis is inflammation of the Appendix (anatomy), appendix. Symptoms commonly include right lower abdominal pain, nausea, vomiting, fever and anorexia (symptom), decreased appetite. However, approximately 40% of people do not have these t ...
or twisted loop of the bowel may also be seen. If the picture is normal a functional cause such as
irritable bowel syndrome Irritable bowel syndrome (IBS) is a functional gastrointestinal disorder characterized by a group of symptoms that commonly include abdominal pain, abdominal bloating, and changes in the consistency of bowel movements. These symptoms may ...
(IBS) may be considered. In a healthy colon, barium should fill the colon uniformly and show normal bowel contour, patency (should be freely open), and position. Additional conditions under which the test may be performed: * CMV gastroenteritis/
colitis Colitis is swelling or inflammation Inflammation (from ) is part of the biological response of body tissues to harmful stimuli, such as pathogens, damaged cells, or irritants. The five cardinal signs are heat, pain, redness, swelling, and ...
*
Hirschsprung's disease Hirschsprung's disease (HD or HSCR) is a birth defect in which nerves are missing from parts of the intestine. The most prominent symptom is constipation. Other symptoms may include vomiting, abdominal pain, diarrhea and slow growth. Most child ...
*
intestinal obstruction Bowel obstruction, also known as intestinal obstruction, is a mechanical or functional obstruction of the intestines which prevents the normal movement of the products of digestion. Either the small bowel or large bowel may be affected. Signs ...
* intussusception (children)


Procedure

Barium enema can be done in two ways, namely double contrast and single contrast methods. Double contrast (where air is inflated into the bowel after excess barium are drained through anus) is useful in visualising mucosal pattern. For single contrast study (whole bowel is filled up with barium without inflating any air), it is used to visualise any obstruction in the large bowel, and it is used in children where visualisation of mucosal pattern is not needed. Barium enema is also used to reduce an intussusception where this disorder is more commonly found in children. 500 ml of Polibar 150% (
barium sulfate suspension Barium sulfate suspension, often simply called barium, is a contrast agent used during X-rays. Specifically it is used to improve visualization of the gastrointestinal tract (esophagus, stomach, intestines) on radiography, plain X-ray or compu ...
) is used to perform this study. Subject should be fasted and Picolax (
sodium picosulfate Sodium picosulfate ( INN, also known as sodium picosulphate) is a contact stimulant laxative used as a treatment for constipation or to prepare the large bowel before colonoscopy or surgery. It is available as a generic medication. Medical u ...
) is taken orally to empty the bowels before barium enema procedure. This test may be done in a hospital or clinic. The individual lies on the X-ray table and a preliminary X-ray is taken. The individual is then asked to lie on their side while a well lubricated
enema An enema, also known as a clyster, is the rectal administration of a fluid by injection into the Large intestine, lower bowel via the anus.Cullingworth, ''A Manual of Nursing, Medical and Surgical'':155 The word ''enema'' can also refer to the ...
tube is inserted into the
rectum The rectum (: rectums or recta) is the final straight portion of the large intestine in humans and some other mammals, and the gut in others. Before expulsion through the anus or cloaca, the rectum stores the feces temporarily. The adult ...
. As the enema enters the body, the individual might have the sensation that they need to have a bowel movement. The barium sulfate, a radiodense (shows as white on X-ray)
contrast medium A contrast agent (or contrast medium) is a substance used to increase the contrast of structures or fluids within the body in medical imaging. Contrast agents absorb or alter external electromagnetism or ultrasound, which is different from radiop ...
, flows through the rectum into the colon. A large balloon at the tip of the enema tube may be inflated to help keep the barium sulfate inside. The flow of the barium sulfate is monitored by the health care provider on an X-ray
fluoroscope Fluoroscopy (), informally referred to as "fluoro", is an imaging technique that uses X-rays to obtain real-time moving images of the interior of an object. In its primary application of medical imaging, a fluoroscope () allows a surgeon to see t ...
screen (like a TV monitor). Air may be puffed into the colon to distend it and provide better images (often called a "double-contrast" exam). If air is used, the enema tube will be reinserted if it had been removed and a small amount of air will be introduced into the colon, and more X-ray pictures are taken. The individual is usually asked to move to different positions and the table is slightly tipped to get different views. If there is a suspected bowel perforation, a water-soluble
contrast agent A contrast agent (or contrast medium) is a substance used to increase the contrast of structures or fluids within the body in medical imaging. Contrast agents absorb or alter external electromagnetism or ultrasound, which is different from radiop ...
(such as diatrizoate) is used instead of barium. The procedure is otherwise very similar, although the images will be of poorer quality. If a perforation exists, the contrast will leak from the bowel to the
peritoneal cavity The peritoneal cavity is a potential space located between the two layers of the peritoneum—the parietal peritoneum, the serous membrane that lines the abdominal wall, and visceral peritoneum, which surrounds the internal organs. While situated ...
; water-soluble material is less obscuring compared to barium should an abdominal incision to remove the contrast be necessary.


Radiographic views

Assume that the x-ray tube is moving above the table and the x-ray film is moving below the table (overcouch): The subject lying supine to give AP (anteroposterior) view of all the bowels. Left lateral view of rectum is to view the rectum from lateral position. Right anterior oblique (RAO) position is to view the caecum, ascending colon, right hepatic flexure and sigmoid colon without overlapping of other bowels. Left anterior oblique (LAO) position is to view the splenic flexure without overlapping of other bowels. Left posterior oblique (LPO) position is to view the sigmoid colon without overlapping of other bowels. Hampton's view (prone caudal view) of rectosigmoid colon is taken when the subject is in prone position with the X-ray tube tilted towards the feet at 30 degrees. This is to separate out the loops of sigmoid colon. Other views include right and left decubitus views


Risks

X-rays are monitored and regulated to provide the minimum amount of radiation exposure needed to produce the image. Most experts feel that the risk is low compared with the benefits. Pregnant women and children are more sensitive to the risks of ionizing radiation. A more serious risk is a bowel perforation.


Special considerations

CT scan A computed tomography scan (CT scan), formerly called computed axial tomography scan (CAT scan), is a medical imaging technique used to obtain detailed internal images of the body. The personnel that perform CT scans are called radiographers or ...
s and
ultrasound Ultrasound is sound with frequency, frequencies greater than 20 Hertz, kilohertz. This frequency is the approximate upper audible hearing range, limit of human hearing in healthy young adults. The physical principles of acoustic waves apply ...
s are now the tests of choice for the initial evaluation of abdominal masses, and colonoscopies are becoming the standard for routine colon screening for those over age 50 or with a familial history of polyps or colon cancer, although it is not uncommon for a barium enema to be done after a colonoscopy for further evaluation.


See also

*
Upper gastrointestinal series An upper gastrointestinal series, also called a barium swallow, barium study, or barium meal, is a series of radiographs used to examine the gastrointestinal tract for abnormalities. A contrast medium, usually a radiocontrast agent such as bariu ...


References


External links


Duplicated Colon on Barium Enema
- MedPix Medical Image Database
RadiologyInfo
- The radiology information resource for patients: Barium Enema

{{Medical imaging Barium Diagnostic gastroenterology Digestive system imaging Fluoroscopy