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A bad trip (also known as challenging experiences, acute intoxication from hallucinogens, psychedelic crisis, or emergence phenomenon) is an acute adverse psychological reaction to the effects of psychoactive substances, namely
psychedelics Psychedelics are a subclass of hallucinogenic drugs whose primary effect is to trigger non-ordinary mental states (known as psychedelic experiences or "trips") and a perceived "expansion of consciousness". Also referred to as classic halluci ...
. There is no clear definition of what constitutes a bad trip. Additionally, knowledge on the cause of bad trips and who may be vulnerable to such experiences are limited. Existing studies report that possible adverse reactions include
anxiety Anxiety is an emotion characterised by an unpleasant state of inner wikt:turmoil, turmoil and includes feelings of dread over Anticipation, anticipated events. Anxiety is different from fear in that fear is defined as the emotional response ...
, panic,
depersonalization Depersonalization is a dissociative phenomenon characterized by a subjective feeling of detachment from oneself, manifesting as a sense of disconnection from one's thoughts, emotions, sensations, or actions, and often accompanied by a feeling of ...
,
ego dissolution Ego death is a "complete loss of subjective self-identity". The term is used in various intertwined contexts, with related meanings. The 19th-century philosopher and psychologist William James uses the synonymous term "self-surrender", and Jungi ...
,
paranoia Paranoia is an instinct or thought process that is believed to be heavily influenced by anxiety, suspicion, or fear, often to the point of delusion and irrationality. Paranoid thinking typically includes persecutory beliefs, or beliefs of co ...
, as well as physiological symptoms such as dizziness and heart palpitations. However, most studies indicate that the ''
set and setting Set and setting, when referring to a psychedelic drug experience or the use of other psychoactive substances, means one's mindset (shortened to "set") and the physical and social environment (the "setting") in which the user has the experience ...
'' of substance use influence how people respond. Bad trips can be exacerbated by the inexperience or irresponsibility of the user or the lack of proper preparation and environment for the trip, and are often reflective of unresolved psychological tensions triggered during the course of the experience. In clinical research settings, precautions including the screening and preparation of participants, the training of the session monitors who will be present during the experience, and the selection of appropriate physical setting can minimize the likelihood of psychological distress. Researchers have suggested that the presence of professional " trip sitters" (i.e., session monitors) may significantly reduce the negative experiences associated with a bad trip. In most cases in which anxiety arises during a supervised psychedelic experience, reassurance from the session monitor is adequate to resolve it; however, if distress becomes intense it can be treated pharmacologically, for example with the
benzodiazepine Benzodiazepines (BZD, BDZ, BZs), colloquially known as "benzos", are a class of central nervous system (CNS) depressant, depressant drugs whose core chemical structure is the fusion of a benzene ring and a diazepine ring. They are prescribed t ...
diazepam Diazepam, sold under the brand name Valium among others, is a medicine of the benzodiazepine family that acts as an anxiolytic. It is used to treat a range of conditions, including anxiety disorder, anxiety, seizures, alcohol withdrawal syndr ...
. The psychiatrist
Stanislav Grof Stanislav Grof (born July 1, 1931) is a Czech-born American psychiatrist. Grof is one of the principal developers of transpersonal psychology and research into the use of non-ordinary states of consciousness for purposes of psychological hea ...
wrote that unpleasant psychedelic experiences are not necessarily unhealthy or undesirable, arguing that they may have the potential for psychological healing and lead to breakthrough and resolution of unresolved psychic issues. Drawing on narrative theory, the authors of a 2021 study of 50 users of psychedelics found that many described bad trips as having been sources of insight or even turning points in life.


Signs and symptoms

With proper screening, preparation, and support in a regulated setting these are usually benign. A bad trip on
psilocybin Psilocybin, also known as 4-phosphoryloxy-''N'',''N''-dimethyltryptamine (4-PO-DMT), is a natural product, naturally occurring tryptamine alkaloid and Investigational New Drug, investigational drug found in more than List of psilocybin mushroom ...
, for instance, often features intense anxiety, confusion, agitation, and
psychosis In psychopathology, psychosis is a condition in which a person is unable to distinguish, in their experience of life, between what is and is not real. Examples of psychotic symptoms are delusions, hallucinations, and disorganized or inco ...
. They manifest as a range of feelings, such as anxiety, paranoia, the unshakeable sense of one's inevitable and imminent personal demise or states of unrelieved terror that they believe will persist after the substance's
effects Effect may refer to: * A result or change of something ** List of effects ** Cause and effect, an idiom describing causality Pharmacy and pharmacology * Drug effect, a change resulting from the administration of a drug ** Therapeutic effect, ...
have worn off. As of 2011, exact data on the frequency of bad trips are not available.


Treatment

Medical treatment consists of supportive therapy and minimization of external stimuli. In some cases,
sedation Sedation is the reduction of irritability or agitation by administration of sedative drugs, generally to facilitate a medical procedure or diagnostic procedure. Examples of drugs which can be used for sedation include isoflurane, diethyl ether, ...
is used when necessary to control self-destructive behavior, or when
hyperthermia Hyperthermia, also known as overheating, is a condition in which an individual's body temperature is elevated beyond normal due to failed thermoregulation. The person's body produces or absorbs more heat than it dissipates. When extreme te ...
occurs.
Diazepam Diazepam, sold under the brand name Valium among others, is a medicine of the benzodiazepine family that acts as an anxiolytic. It is used to treat a range of conditions, including anxiety disorder, anxiety, seizures, alcohol withdrawal syndr ...
is the most frequently used sedative for such treatment, but other
benzodiazepines Benzodiazepines (BZD, BDZ, BZs), colloquially known as "benzos", are a class of central nervous system (CNS) depressant drugs whose core chemical structure is the fusion of a benzene ring and a diazepine ring. They are prescribed to treat co ...
such as
lorazepam Lorazepam, sold under the brand name Ativan, Tavor among others, is a benzodiazepine medication. It is used to treat anxiety (including anxiety disorders), insomnia, severe agitation, active seizures including status epilepticus, alcoh ...
are also effective. Such sedatives will only decrease fear and anxiety, but will not subdue hallucinations. In severe cases, antipsychotics such as
haloperidol Haloperidol, sold under the brand name Haldol among others, is a typical antipsychotic medication. Haloperidol is used in the treatment of schizophrenia, tics in Tourette syndrome, mania in bipolar disorder, delirium, agitation, acute psychos ...
can reduce or stop hallucinations. Haloperidol is effective against acute intoxication caused by LSD and other
tryptamine Tryptamine is an indolamine metabolite of the essential amino acid tryptophan. The chemical structure is defined by an indole—a fused benzene and pyrrole ring, and a 2-aminoethyl group at the second carbon (third aromatic atom, with the firs ...
s,
amphetamine Amphetamine (contracted from Alpha and beta carbon, alpha-methylphenethylamine, methylphenethylamine) is a central nervous system (CNS) stimulant that is used in the treatment of attention deficit hyperactivity disorder (ADHD), narcolepsy, an ...
s,
ketamine Ketamine is a cyclohexanone-derived general anesthetic and NMDA receptor antagonist with analgesic and hallucinogenic properties, used medically for anesthesia, depression, and pain management. Ketamine exists as its S- (esketamine) a ...
, and
phencyclidine Phencyclidine or phenylcyclohexyl piperidine (PCP), also known in its use as a street drug as angel dust among other names, is a dissociative anesthetic mainly used recreationally for its significant mind-altering effects. PCP may cause hall ...
.


Pathophysiology

Bad trips may cause range of conditions such as
psychosis In psychopathology, psychosis is a condition in which a person is unable to distinguish, in their experience of life, between what is and is not real. Examples of psychotic symptoms are delusions, hallucinations, and disorganized or inco ...
and
hallucinogen persisting perception disorder Hallucinogen persisting perception disorder (HPPD) is a non-psychotic disorder in which a person experiences apparent lasting or persistent visual hallucinations or perceptual distortions after using drugs, including but not limited to psychedeli ...
(HPPD).


Perspectives


Stanislav Grof

Psychiatrist
Stanislav Grof Stanislav Grof (born July 1, 1931) is a Czech-born American psychiatrist. Grof is one of the principal developers of transpersonal psychology and research into the use of non-ordinary states of consciousness for purposes of psychological hea ...
once said in an interview: In a 1975 book, Grof suggested that painful and difficult experiences during a trip could be a result of the mind reliving experiences associated with birth, and that experiences of imprisonment,
eschatological Eschatology (; ) concerns expectations of the end of present age, human history, or the world itself. The end of the world or end times is predicted by several world religions (both Abrahamic and non-Abrahamic), which teach that negative world ...
terror, or suffering far beyond anything imaginable in a normal state, if seen through to conclusion, often resolve into emotional, intellectual and spiritual breakthroughs. From this perspective, Grof suggests that interrupting a bad trip, while initially seen as beneficial, could potentially trap the tripper in unresolved psychological states. Grof also suggests that many cathartic experiences within psychedelic states, while not necessarily crises, may be the effects of consciousness entering a perinatal space.


Rick Strassman

Professor of psychiatry
Rick Strassman Rick Strassman is an American clinical associate professor of psychiatry at the University of New Mexico School of Medicine. He has held a fellowship in clinical psychopharmacology research at the University of California San Diego and was Profes ...
is critical of reframing the experience of bad trips as one of "challenging experiences".


See also

*
Altered state of consciousness An altered state of consciousness (ASC), also called an altered state of mind, altered mental status (AMS) or mind alteration, is any condition which is significantly different from a normal waking state. It describes induced changes in one's me ...
*
Ego death Ego death is a "complete loss of subjective self-identity". The term is used in various intertwined contexts, with related meanings. The 19th-century philosopher and psychologist William James uses the synonymous term "self-surrender", and Jung ...
*
Existential crisis Existential crises are inner conflicts characterized by the impression that life lacks meaning and confusion about one's personal identity. They are accompanied by anxiety and stress, often to such a degree that they disturb one's normal funct ...
* Hard and soft drugs *
Harm reduction Harm reduction, or harm minimization, refers to a range of intentional practices and public health policies designed to lessen the negative social and/or physical consequences associated with various human behaviors, both legal and illegal. H ...
*
Lucid dreaming In the psychology subfield of oneirology, a lucid dream is a type of dream wherein the dreamer realizes that they are dreaming during their dream. The capacity to have lucid dreams is a trainable cognitive skill. During a lucid dream, the dreamer ...
*
Near-death experience A near-death experience (NDE) is a profound personal experience associated with death or impending death, which researchers describe as having similar characteristics. When positive, which the great majority are, such experiences may encompa ...
*
Out-of-body experience An out-of-body experience (OBE or sometimes OOBE) is a phenomenon in which a person perceives the world as if from a location outside their physical body. An OBE is a form of autoscopy (literally "seeing self"), although this term is more common ...
*
Overdose A drug overdose (overdose or OD) is the ingestion or application of a drug or other substance in quantities much greater than are recommended. Retrieved on September 20, 2014.
* Posttraumatic growth *
Posttraumatic stress disorder Post-traumatic stress disorder (PTSD) is a mental disorder that develops from experiencing a Psychological trauma, traumatic event, such as sexual assault, domestic violence, child abuse, warfare and its associated traumas, natural disaster ...
*
Psychedelic experience A psychedelic experience (known colloquially as a trip) is a temporary altered state of consciousness induced by the consumption of a psychedelic substance (most commonly Lysergic acid diethylamide, LSD, mescaline, psilocybin mushrooms, or N,N- ...
* Psychedelic therapy *
Psychedelics, dissociatives and deliriants Hallucinogens, also known as psychedelics, entheogens, or historically as psychotomimetics, are a large and diverse class of psychoactive drugs that can produce altered states of consciousness characterized by major alterations in thought, mo ...
* Psychonautics *
Psychosis In psychopathology, psychosis is a condition in which a person is unable to distinguish, in their experience of life, between what is and is not real. Examples of psychotic symptoms are delusions, hallucinations, and disorganized or inco ...
*
Recreational drug use Recreational drug use is the use of one or more psychoactive drugs to induce an altered state of consciousness, either for pleasure or for some other casual purpose or pastime. When a psychoactive drug enters the user's body, it induces an Sub ...
*
Responsible drug use Responsible drug use seeks to maximize the benefits and minimize the risks associated with psychoactive drug use. For illegal psychoactive drugs that are not diverted prescription controlled substances, some critics believe that illegal recreationa ...
*
Sensory deprivation Sensory deprivation or perceptual isolation is the deliberate reduction or removal of stimuli from one or more of the senses. Simple devices such as blindfolds or hoods and earmuffs can cut off sight and hearing, while more complex devices can ...
*
Set and setting Set and setting, when referring to a psychedelic drug experience or the use of other psychoactive substances, means one's mindset (shortened to "set") and the physical and social environment (the "setting") in which the user has the experience ...
*
Spiritual crisis Spiritual crisis (also called "spiritual emergency") is a form of identity crisis where an individual experiences drastic changes to their meaning system (i.e., their unique purposes, goals, values, attitude and beliefs, identity, and focus) typi ...


References


External links


Crisis Intervention in Situations Related to Unsupervised Use of Psychedelics

Psychedelic Crisis FAQ: Helping someone through a bad trip, psychic crisis, or spiritual crisis

Psychedelic Harm Reduction

Psychedelic Harm Reduction and Policy
lecture in the Psychedelic Science in the 21st Century conference in 2010.
Psychedelics in the Psychiatric ER - Julie Holland, M.D.
lecture in the Psychedelic Science in the 21st Century conference in 2010.
The Psychedelic crisis (bad trip) entry at Drugs-Wiki
{{DEFAULTSORT:Bad Trip Drug culture Drug overdose Psychedelia Substance intoxication