Azatadine (Optimine) is a
first-generation antihistamine
H1 antagonists, also called H1 blockers, are a class of medications that block the action of histamine at the H1 receptor, helping to relieve allergic reactions. Agents where the main therapeutic effect is mediated by negative modulation of ...
and
anticholinergic
Anticholinergics (anticholinergic agents) are substances that block the action of the neurotransmitter called acetylcholine (ACh) at synapses in the central and peripheral nervous system.
These agents inhibit the parasympathetic nervous syste ...
that was launched by
Schering-Plough
Schering-Plough Corporation was an American pharmaceutical company. It was originally the U.S. subsidiary of the German company Schering AG, which was founded in 1851 by Ernst Christian Friedrich Schering. As a result of nationalization, it bec ...
in 1973.
It was patented in 1967. It has been succeeded by both
loratadine
Loratadine, sold under the brand name Claritin among others, is a medication used to treat allergies. This includes allergic rhinitis (hay fever) and hives. It is also available in combination with pseudoephedrine, a decongestant, known as lor ...
and
desloratadine. and marketing approvals have been widely withdrawn.
See also
*
Azatadine/pseudoephedrine
Azatadine/pseudoephedrine (''Trinalin'') is an antihistamine and decongestant formulation. It is a combination drug containing azatadine maleate and pseudoephedrine sulfate
The sulfate or sulphate ion is a polyatomic ion, polyatomic anion wi ...
References
Piperidines
Benzocycloheptapyridines
H1 receptor antagonists
Abandoned drugs
1973 introductions
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