Avicularin is a bio-active

flavonol Flavonols are a class of flavonoids that have the 3-hydroxyflavone backbone (IUPAC name : 3-hydroxy-2-phenylchromen-4-one). Their diversity stems from the different positions of the phenolic -OH groups. They are distinct from flavanols (with " ...

isolated from a number of plants including ''

Polygonum aviculare ''Polygonum aviculare'' or common knotgrass is a plant related to buckwheat and dock. It is also called prostrate knotweed, birdweed, pigweed and lowgrass. It is an annual found in fields and wasteland, with white flowers from June to October. ...

'',LC Method for Analysis of Three Flavonols in Rat Plasma and Urine after Oral Administration of Polygonum aviculare Extract. Fuquan Xu, Huashi Guan, Guoqiang Li and Hongbing Liu, Chromatographia, June 2009, Volume 69, Issue 11-12, pages 1251-1258, ''

Rhododendron aureum ''Rhododendron aureum'' is a flowering plant species in the genus ''Rhododendron''. Larvae of ''Boloria freija'' feed on ''Rhododendron aureum''. ''R. aureum'' produces (-)- rhododendrol, (-)- rhododendrin, avicularin and hyperoside Hyperosi ...

'' and ''

Taxillus kaempferi ''Taxillus kaempferi'' () is a parasitic plant species in the genus ''Taxillus'' found in China (Anhui, Fujian, W Hubei, S Jiangxi, Sichuan, S Zhejiang), Bhutan and Japan. Its host is ''Pinus thunbergii''.The constituents of Taxillus kaempferi an ...

''.Avicularin, a plant flavonoid, suppresses lipid accumulation through repression of C/EBPα-activated GLUT4-mediated glucose uptake in 3T3-L1 cells. Fujimori K and Shibano M, J Agric Food Chem., 29 May 2013, volume 61, issue 21, pages 5139-5147, , It suppresses lipid accumulation through repression of C/EBPα-activated

GLUT4 Glucose transporter type 4 (GLUT4), also known as solute carrier family 2, facilitated glucose transporter member 4, is a protein encoded, in humans, by the ''SLC2A4'' gene. GLUT4 is the insulin-regulated glucose transporter found primarily in a ...

-mediated glucose uptake in

3T3-L1 3T3-L1 is a cell line derived from (mouse) 3T3 cells that is used in biological research on adipose tissue. 3T3-L1 cells have a fibroblast-like morphology, but, under appropriate conditions, the cells differentiate into an adipocyte-like phenotype. ...

cells.

References

Flavonol glycosides Arabinosides Hydroxymethyl compounds {{aromatic-stub