Avery Sandberg
   HOME

TheInfoList



OR:

Avery A. Sandberg (29 January 1921 – 6 July 2016) was one of the founding fathers of cancer research and made key contributions to hematology.


Early life

Avery A. Sandberg was born on January 29, 1921, in
Sarny Sarny (, ) is a small city in Rivne Oblast, western Ukraine. It is the administrative center of Sarny Raion within the oblast and is a major railway node on the Sluch River. Population: Etymology The city is named after the roe deer and can ...
,
Ukraine Ukraine is a country in Eastern Europe. It is the List of European countries by area, second-largest country in Europe after Russia, which Russia–Ukraine border, borders it to the east and northeast. Ukraine also borders Belarus to the nor ...
(then
Poland Poland, officially the Republic of Poland, is a country in Central Europe. It extends from the Baltic Sea in the north to the Sudetes and Carpathian Mountains in the south, bordered by Lithuania and Russia to the northeast, Belarus and Ukrai ...
) and died at the age of 95 on July 6, 2016, in
Scottsdale, Arizona Scottsdale is a city in eastern Maricopa County, Arizona, United States, and is part of the Phoenix metropolitan area. Named Scottsdale in 1894 after its founder Winfield Scott (chaplain), Winfield Scott, a retired Chaplain Corps (United States ...
. Avery Sandberg was the eldest of three brothers - Avery, Arthur, and Hershel to their parents, Rivka Shapiro Sandberg and Jacob Sandberg. The Sandberg family lived in a wooden house on Tolstoho Street without central heating or electricity. Once a week, pails of water from a well two blocks away would be carried home for the family to take a bath. As Jewish people, they were not allowed to live near or go to school with the Polish. Sarny was a Jewish community with its own Hebrew schools and
synagogue A synagogue, also called a shul or a temple, is a place of worship for Jews and Samaritans. It is a place for prayer (the main sanctuary and sometimes smaller chapels) where Jews attend religious services or special ceremonies such as wed ...
. However, the community often experienced
anti-Semitism Antisemitism or Jew-hatred is hostility to, prejudice towards, or discrimination against Jews. A person who harbours it is called an antisemite. Whether antisemitism is considered a form of racism depends on the school of thought. Antisemi ...
both verbally and physically by passing soldiers or Polish people. According to Hershel in an interview with the Holocaust Memorial Center, Avery got beaten up after attending a Polish school for a single day. Instead, Avery went to a Hebrew school in Rovno where he was taught English. Jacob, an avid reader of German, Russian, Polish, and Jewish newspapers, predicted what would become
World War II World War II or the Second World War (1 September 1939 – 2 September 1945) was a World war, global conflict between two coalitions: the Allies of World War II, Allies and the Axis powers. World War II by country, Nearly all of the wo ...
in the coming years. He applied for United States passports for the family in 1932, but did not receive them until 1936 when his brother-in-law, Levi Shapiro, who lived in the U.S. delivered them. In 1938, one year before World War II started, the Sandberg's boarded the ship ''Lancastria'' where they sailed from Sarny to Danzig and then Liverpool. They lived in camps for six weeks in Liverpool, until they sailed twelve more days to Ireland and finally the United States. They arrived in New York in March 1938, moved in with Avery's grandparents, Simcha and Anna Shapiro, on Elmhurst Street in
Detroit Detroit ( , ) is the List of municipalities in Michigan, most populous city in the U.S. state of Michigan. It is situated on the bank of the Detroit River across from Windsor, Ontario. It had a population of 639,111 at the 2020 United State ...
, but ultimately settled into their own home in Fullerton, Detroit. Both Avery and Arthur started school, while Hershel attended an intermediate school to catch up on his English. Jacob worked in a butcher shop where the boys would flick chickens every Wednesday for their father to sell Thursdays and Fridays. In the 1940s, Avery and Arthur went to
Wayne State University Wayne State University (WSU) is a public university, public research university in Detroit, Michigan, United States. Founded in 1868, Wayne State consists of 13 schools and colleges offering approximately 375 programs. It is Michigan's third-l ...
. Avery graduated in 1946 where he went on to study
hematology Hematology (American and British English spelling differences#ae and oe, spelled haematology in British English) is the branch of medicine concerned with the study of the cause, prognosis, treatment, and prevention of diseases related to bloo ...
and research cancer genetics after his uncle and father both died of brain tumors.


Career and legacy

Most of Sandberg's hematology and
cancer research Cancer research is research into cancer to identify causes and develop strategies for prevention, diagnosis, treatment, and cure. Cancer research ranges from epidemiology, molecular bioscience to the performance of clinical trials to evaluate ...
started in the laboratories at the
University of Utah The University of Utah (the U, U of U, or simply Utah) is a public university, public research university in Salt Lake City, Utah, United States. It was established in 1850 as the University of Deseret (Book of Mormon), Deseret by the General A ...
where he became a member and scholar of the
American Cancer Society The American Cancer Society (ACS) is a nationwide non-profit organization dedicated to eliminating cancer. The ACS publishes the journals ''Cancer'', '' CA: A Cancer Journal for Clinicians'' and '' Cancer Cytopathology''. History The society w ...
. In 1958, Sandberg worked as a professor of medicine and was appointed the head of the Department of Genetics and Endocrinology at the Roswell Park Cancer Institute where he furthered his research. Sandberg and colleagues in
Buffalo, New York Buffalo is a Administrative divisions of New York (state), city in the U.S. state of New York (state), New York and county seat of Erie County, New York, Erie County. It lies in Western New York at the eastern end of Lake Erie, at the head of ...
published the first report of a man with a
47,XYY XYY syndrome, also known as Jacobs syndrome, is an aneuploid genetic condition in which a male has an extra Y chromosome. There are usually few symptoms. These may include being taller than average and an increased risk of learning disabilities ...
karyotype A karyotype is the general appearance of the complete set of chromosomes in the cells of a species or in an individual organism, mainly including their sizes, numbers, and shapes. Karyotyping is the process by which a karyotype is discerned by de ...
in 1961. He was also the editor and chief of one of the first scientific journals on cancer
cytogenetics Cytogenetics is essentially a branch of genetics, but is also a part of cell biology/cytology (a subdivision of human anatomy), that is concerned with how the chromosomes relate to cell behaviour, particularly to their behaviour during mitosis an ...
in 1979 called "Cancer Genetics and Cytogenetics." Shortly after, he wrote his first book called ''The Chromosomes in Human Cancer and Leukemia''. He taught at the University of Buffalo School of Medicine in New York before moving to Arizona with his wife, Maryn Sandberg, and four daughters, Diana, Jan, Ruth, and Nina, in 1986. In Arizona, Sandberg continued his teaching career at the
University of Arizona College of Medicine A university () is an institution of tertiary education and research which awards academic degrees in several academic disciplines. ''University'' is derived from the Latin phrase , which roughly means "community of teachers and scholars". Uni ...
as a professor of medicine and
pathology Pathology is the study of disease. The word ''pathology'' also refers to the study of disease in general, incorporating a wide range of biology research fields and medical practices. However, when used in the context of modern medical treatme ...
. As of 1999, Sandberg was a consultant with the DNA Diagnostics Laboratory at St. Joseph's Hospital and Medical Center in Phoenix with no interest in retirement. He spent his free time collecting art and lecturing at community centers about the history of the
Jews Jews (, , ), or the Jewish people, are an ethnoreligious group and nation, originating from the Israelites of History of ancient Israel and Judah, ancient Israel and Judah. They also traditionally adhere to Judaism. Jewish ethnicity, rel ...
. After his wife Maryn died in June 2013, Avery Sandberg followed three years later.


Selected books

* ''The Y Chromosome, Part B: Clinical Aspects of Y Chromosome Abnormalities'' (1985) * ''The chromosomes in human cancer and leukemia'' (1990)


References

{{DEFAULTSORT:Sandberg, Avery American geneticists 1921 births 2016 deaths