Auxiliary Activity family 9 (formerly GH61) is a

family Family (from ) is a Social group, group of people related either by consanguinity (by recognized birth) or Affinity (law), affinity (by marriage or other relationship). It forms the basis for social order. Ideally, families offer predictabili ...

of lytic polysaccharide

monooxygenase Monooxygenases are enzymes that incorporate one hydroxyl group (−OH) into substrates in many metabolic pathways. In this reaction, the two atoms of dioxygen are reduced to one hydroxyl group and one H2O molecule by the concomitant oxidation of ...

s. The family was previously incorrectly classified as glycoside hydrolase family 61, however it was re-classified in March 2013. AA9 is known to be a copper dependent, oxidative enzyme able to cleave crystalline cellulose. Activity greatly depends on the presence of a divalent copper ion and a reductant such as gallate or ascorbate. The oxidative action of AA9 can work on either the reducing or the non-reducing end of glucose moieties. Although AA9 enzymes can be found in a large spectrum of biomass degrading fungi, research into this family is relatively new. This classification is available on the

CAZy CAZy is a database of Carbohydrate-Active enZYmes (CAZymes). The database contains a classification and associated information about enzymes involved in the synthesis, metabolism, and recognition of complex carbohydrates, i.e. disaccharides, oli ...

web site, and also discussed at CAZypedia, an online encyclopedia of carbohydrate active enzymes.

References

{{Portal bar, Biology, border=no EC 3.2.1 Glycoside hydrolase families Protein families