
Augustus Volney Waller
FRS (21 December 1816 – 18 September 1870) was a British neurophysiologist. He was the first to describe the degeneration of severed
nerve fiber
An axon (from Greek ἄξων ''áxōn'', axis) or nerve fiber (or nerve fibre: see spelling differences) is a long, slender projection of a nerve cell, or neuron, in vertebrates, that typically conducts electrical impulses known as action pot ...
s, now known as
Wallerian degeneration
Wallerian degeneration is an active process of degeneration that results when a nerve fiber is cut or crushed and the part of the axon distal to the injury (which in most cases is farther from the neuron's cell body) degenerates. A related process ...
.
Life
The son of William Waller of Elverton Farm, near
Faversham
Faversham () is a market town in Kent, England, from Sittingbourne, from London and from Canterbury, next to the Swale, a strip of sea separating mainland Kent from the Isle of Sheppey in the Thames Estuary. It is close to the A2 road (Great ...
,
Kent
Kent is a Ceremonial counties of England, ceremonial county in South East England. It is bordered by Essex across the Thames Estuary to the north, the Strait of Dover to the south-east, East Sussex to the south-west, Surrey to the west, and Gr ...
, was born on 21 December 1816. His youth was spent at
Nice
Nice ( ; ) is a city in and the prefecture of the Alpes-Maritimes department in France. The Nice agglomeration extends far beyond the administrative city limits, with a population of nearly one million[Tewkesbury
Tewkesbury ( ) is a market town and civil parish in the north of Gloucestershire, England. The town grew following the construction of Tewkesbury Abbey in the twelfth century and played a significant role in the Wars of the Roses. It stands at ...]
, and afterwards with
William Lambe the
vegetarian
Vegetarianism is the practice of abstaining from the Eating, consumption of meat (red meat, poultry, seafood, insects as food, insects, and the flesh of any other animal). It may also include abstaining from eating all by-products of animal slau ...
. His father sharing Lambe's views, Augustus was brought up until the age of eighteen on a vegetarian diet.
Waller studied in Paris, where he obtained the degree of M.D. in 1840, and in the following year he was admitted a licentiate of the
Society of Apothecaries
The Worshipful Society of Apothecaries of London is one of the livery companies of the City of London. It is one of the largest livery companies (with over 1,600 members in 2012) and ranks 58th in their order of precedence.
The society is a me ...
in London. He then entered general medical practice at St. Mary Abbott's Terrace,
Kensington
Kensington is an area of London in the Royal Borough of Kensington and Chelsea, around west of Central London.
The district's commercial heart is Kensington High Street, running on an east–west axis. The north-east is taken up by Kensingt ...
. He soon acquired a considerable practice, but after the publication of two papers in the ''
Philosophical Transactions
''Philosophical Transactions of the Royal Society'' is a scientific journal published by the Royal Society. In its earliest days, it was a private venture of the Royal Society's secretary. It was established in 1665, making it the second journ ...
'' for 1849 and 1850, he was elected a
Fellow of the Royal Society
Fellowship of the Royal Society (FRS, ForMemRS and HonFRS) is an award granted by the Fellows of the Royal Society of London to individuals who have made a "substantial contribution to the improvement of natural science, natural knowledge, incl ...
in 1851. He gave up his practice the same year, and left England to live at
Bonn
Bonn () is a federal city in the German state of North Rhine-Westphalia, located on the banks of the Rhine. With a population exceeding 300,000, it lies about south-southeast of Cologne, in the southernmost part of the Rhine-Ruhr region. This ...
and carry on his scientific work. Here he became associated with Professor
Julius Ludwig Budge, and published papers in the ''Comptes Rendus'' for 1851 and 1852, on physiological subjects. For these papers he was awarded the Monthyon prize of the
French Academy of Sciences
The French Academy of Sciences (, ) is a learned society, founded in 1666 by Louis XIV at the suggestion of Jean-Baptiste Colbert, to encourage and protect the spirit of French Scientific method, scientific research. It was at the forefron ...
for 1852, and for further work this prize was given to him a second time in 1856. The president and council of the Royal Society also awarded him one of their royal medals in 1860 in recognition of the importance of his physiological methods and researches.
Waller left Bonn in 1856, and went to Paris to continue his work in
Flourens's laboratory at the
Jardin des Plantes
The Jardin des Plantes (, ), also known as the Jardin des Plantes de Paris () when distinguished from other ''jardins des plantes'' in other cities, is the main botanical garden in France. Jardin des Plantes is the official name in the present da ...
; but he soon contracted some form of infection, which left him an invalid for the next two years. He returned to England, and, his health improving, he accepted in 1858 the appointment of professor of physiology in
Queen's College, Birmingham
Queen's College was a medical school in central Birmingham, England, and a predecessor college of the University of Birmingham. It was founded by surgeon William Sands Cox in 1825 as The Birmingham Medical School, a residential college for med ...
(a predecessor college of
Birmingham University
The University of Birmingham (informally Birmingham University) is a Public university, public research university in Birmingham, England. It received its royal charter in 1900 as a successor to Queen's College, Birmingham (founded in 1825 as ...
), and the post of physician to the hospital. These appointments he did not long retain. The heart affection which eventually proved fatal led him to seek rest, and, after staying two years longer in England, he retired first to
Bruges
Bruges ( , ; ; ) is the capital and largest city of the province of West Flanders, in the Flemish Region of Belgium. It is in the northwest of the country, and is the sixth most populous city in the country.
The area of the whole city amoun ...
and afterwards to Switzerland.
Works
With renewed health, he moved to
Geneva
Geneva ( , ; ) ; ; . is the List of cities in Switzerland, second-most populous city in Switzerland and the most populous in French-speaking Romandy. Situated in the southwest of the country, where the Rhône exits Lake Geneva, it is the ca ...
in 1868, with the purpose of practising as a physician, and he was almost immediately elected a member of the Société de Physique et d'Histoire Naturelle there. He paid a short visit to London in the spring of 1869 to deliver the
Croonian lecture
The Croonian Medal and Lecture is a prestigious award, a medal, and lecture given at the invitation of the Royal Society and the Royal College of Physicians.
Among the papers of William Croone at his death in 1684, was a plan to endow a singl ...
before the Royal Society, and he afterwards returned to Geneva, where he died suddenly of
angina pectoris
Angina, also known as angina pectoris, is chest pain or pressure, usually caused by insufficient blood flow to the heart muscle (myocardium). It is most commonly a symptom of coronary artery disease.
Angina is typically the result of part ...
on 18 September 1870.
He demonstrated the
cilio-spinal centre
The ciliospinal center (also known as Budge's center) is a cluster of pre-ganglionic sympathetic neuron cell bodies located in the intermediolateral cell column (of the cornu laterale) at spinal cord segment (C8: ''Anatomic variation'') T1-T2
It ...
in the
spinal cord
The spinal cord is a long, thin, tubular structure made up of nervous tissue that extends from the medulla oblongata in the lower brainstem to the lumbar region of the vertebral column (backbone) of vertebrate animals. The center of the spinal c ...
and the
vasoconstrictor
Vasoconstriction is the narrowing of the blood vessels resulting from contraction of the muscular wall of the vessels, in particular the large arteries and small arterioles. The process is the opposite of vasodilation, the widening of blood vesse ...
action of the sympathetic; and he invented the degeneration method of studying the paths of nerve impulses. He practically rediscovered the power which the
white corpuscles possess of escaping from the smallest blood-vessels, while some of his earlier work was concerned with purely physical problems.
The most important of Waller's papers are to be found in the ‘Comptes Rendus,’ in the ‘Philosophical Magazine,’ and in the ‘Philosophical Transactions.’ The Wallerian degeneration is described in the ‘Comptes Rendus,’ 1 Dec. 1851. The demonstration of the cilio-spinal centre was the result of work done jointly with Professor Budge, and is described in the ‘Comptes Rendus’ for October 1851. The function of the
ganglion
A ganglion (: ganglia) is a group of neuron cell bodies in the peripheral nervous system. In the somatic nervous system, this includes dorsal root ganglia and trigeminal ganglia among a few others. In the autonomic nervous system, there are ...
on the posterior root of each spinal nerve is published in the ‘Comptes Rendus’ (xxxv. 524). ‘The Microscopic Observations on the Perforation of the Capillaries by the Corpuscles of the Blood, and on the Origin of Mucus and Pus,’ appeared in the ‘Philosophical Magazine’ for November 1846, while the ‘Microscopic Investigations on Hail’ were printed in the same journal for July and August 1846 and March 1847.
Family
He married, in 1842, Matilda, only daughter of John Walls of North End, Fulham, and by her had one son,
Augustus Desiré Waller
Augustus Desiré Waller FRS (12 July 1856 – 11 March 1922) was a British physiologist and the son of Augustus Volney Waller. He was born in Paris, France.
Career
He studied medicine at Aberdeen University, where he qualified in 1878 and ob ...
, M.D., F.R.S., the physiologist, and two daughters.
References
*
External links
* http://www.whonamedit.com/doctor.cfm/2383.html
;Attribution
{{DEFAULTSORT:Waller, Augustus Volney
Fellows of the Royal Society
1816 births
1870 deaths
Royal Medal winners
Academics of the University of Birmingham